Mariners vs Astros Prediction and MLB Tips - 21 July 2025
Last updated: Jul 20, 2025, 8:10PM | Published: Jul 20, 2025, 1:43AM
The Seattle Mariners will take on the Houston Astros in MLB action at T-Mobile Park on Monday, commencing at 6:10am AEST.
The Mariners will have Bryan Woo (8-4, 2.75 ERA) start, up against Hunter Brown (9-4, 2.43 ERA) for the Astros.
This article features Stats Insider's prediction and tips for the Mariners vs Astros game, as well as the latest betting odds in Australia.
Who Will Win?
Utilising advanced machine learning and data, Stats Insider has simulated the outcome of Monday's Seattle vs Houston MLB game 10,000 times.
Our leading predictive analytics model currently gives the Mariners a 58% chance of beating the Astros at T-Mobile Park.
Mariners vs Astros: Odds
The current betting odds in Australia for Monday's MLB game at T-Mobile Park are shown here:
- Head to Head: Mariners $1.67, Astros $2.25
- Line: Mariners -1.5 ($2.60), Astros +1.5 ($1.53)
- Total (Over/Under 6.5 Runs): Over $1.91, Under $1.91
Odds are correct at the time of publication and subject to change.
Looking at the latest head-to-head odds, the bookmakers currently have the Mariners at $1.67 and the Astros at $2.25.
The Mariners are 1.5-run favourites against the Astros, with odds of $2.60 available at TAB.
For the underdog Astros (+1.5) to cover the line, TAB offers odds of $1.53.
The over/under for total runs scored is set at 6.5 with TAB, which has odds of $1.91 for the over and $1.91 for the under.
According to Stats Insider's analytics model, the Astros (+1.5) are predicted to cover the line 63% of the time, while the 6.5-run over/under is expected to is considered an equal 50-50 chance of hitting.
Mariners vs Astros: Betting Tips
- Head to Head: Seattle at $1.67 with TAB
- Line: Mariners -1.5 at $2.60 with TAB
- Total Runs: Over 6.5 at $1.91 with TAB
Our Mariners vs Astros best bets are based on world-class simulations and betting expertise to help you place better bets with your chosen online bookie.
Although the Astros are more likely to cover the line, our best bet of Mariners -1.5 is based on the probability of that happening, as projected by our predictive analytics model, and the best odds available.
Mariners vs Astros: Prediction
Stats Insider provides full coverage of the Seattle vs Houston game on Monday, including data-driven predictions and live scorestips.
Our model updates regularly, so keep checking this article for the latest betting tips before the Seattle vs Houston match-up.
As always, see Stats Insider's Best Bets for the best tips for every MLB game, as well as predictions for a wide range of other sports.
Mariners vs Astros: Essential Details
The game between the Mariners and Astros at T-Mobile Park is scheduled to commence at 6:10am AEST on Monday.
- Teams: Seattle Mariners vs Houston Astros
- Date: Monday 21 July 2025
- Time: 6:10am AEST
- Venue: T-Mobile Park
All dates and times mentioned in this article are in Australian Eastern Standard Time (AEST), unless otherwise noted.
Conclusion
Our Seattle vs Houston predictions have been made after running 10,000 data-driven simulations of the game, all curated by our team of experienced data scientists and analysts. We use cutting-edge technology and machine learning to ensure our MLB tips are accurate and reliable, giving you the confidence to make informed decisions.
If you decide to use our predictions for betting purposes, it's important that you gamble responsibly and know when to stop. For free and confidential support, call 1800 858 858 or visit gamblinghelponline.org.au.
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