Lions vs Patriots Prediction and Preview - NFL Week 10, 2026
Last updated: Nov 9, 2026, 2:51AM | Published: Nov 8, 2026, 5:02AM
The Detroit Lions will take on the New England Patriots in NFL Week 10 action at Allianz Arena on Monday, November 16, commencing at 1:30am AEDT.
This article features Stats Insider's top betting tips for the Lions vs Patriots game, as well as the latest betting odds in Australia.
Who Will Win?
Using trusted machine learning and data, Stats Insider has simulated the result of Patriots vs Lions 10,000 times.
Our leading predictive analytics model currently gives the Lions a 59% chance of beating the Patriots in Week 10 of the NFL season.
Lions vs Patriots: Odds
The latest Bet365 betting odds in Australia for this NFL game at Allianz Arena are listed here:
- Head to Head: Lions $1.68, Patriots $2.23
- Line: Lions -2.5 ($1.91), Patriots +2.5 ($1.91)
- Total (Over/Under 50.5 Points): Over $1.91, Under $1.91
Odds are correct at the time of publication and subject to change.
Looking at the latest head-to-head odds, Bet365 currently has the Lions at $1.68 and the Patriots at $2.23.
The Lions are 2.5-point favourites against the Patriots, with odds of $1.91 available at Bet365.
For the underdog Patriots (+2.5) to cover the line, Bet365 offers odds of $1.91.
The over/under for total points scored is set at 50.5 with Bet365, which has odds of $1.91 for the over and $1.91 for the under.
According to Stats Insider's model, the Patriots (+2.5) are predicted to cover the line 53% of the time, while the 50.5-point over/under is expected to stay under 51% of the time.
Lions vs Patriots: Betting Tips
- Head to Head: Detroit at $1.68 with Bet365
- Line: Patriots +2.5 at $1.91 with Bet365
- Total Points: Under 50.5 at $1.91 with Bet365
Our Lions vs Patriots predictions are based on market-leading simulations and betting intelligence to bring you the best possible advice around the clock.
Lions vs Patriots: Prediction
Stats Insider's predicted final score for Lions vs Patriots at Allianz Arena in Week 10 is the Lions winning 26-24.
This prediction is based on each team's average score following 10,000 game simulations.
Stats Insider provides full coverage of the Detroit vs New England game in Week 10, including data-driven predictions and live win probabilitiestips.
18+. Odds correct at time of publishing and subject to change.Remember, our model updates regularly, so keep checking this page for the latest betting analysis before the Detroit vs New England match-up.
As always, see Stats Insider's Best Bets for the best tips for every NFL game, plus predictions for a wide range of other sports.
Lions vs Patriots: Week 10 Essential Details
The NFL Week 10 match-up between the Lions and Patriots at Allianz Arena is scheduled to commence at 1:30am AEDT on Monday, November 16.
- Teams: Detroit Lions vs New England Patriots
- Date: Monday 16 November 2026
- Time: 1:30am AEDT
- Venue: Allianz Arena
All dates and times in this article are in Australian Eastern Daylight Time (AEDT), unless otherwise stated.
Conclusion
Our Detroit vs New England predictions are the result of 10,000 data-driven simulations of the game, all curated by our team of skilled data scientists and analysts. We use cutting-edge technology and machine learning to ensure our NFL tips are accurate and reliable, so that you can make informed decisions with confidence.
If you decide to use our predictions for betting purposes, it's important that you gamble responsibly and keep track of your money. For free and confidential support, call 1800 858 858 or visit gamblinghelponline.org.au.
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