Lions vs Giants Prediction and Preview - NFL Week 12, 2025

The Detroit Lions will take on the New York Giants in NFL Week 12 action at Ford Field on Monday, November 24, beginning at 5:00am AEDT.

This article features Stats Insider's prediction and tips for the Lions vs Giants game, along with the latest betting odds in Australia.

Who Will Win?

Based on trusted machine learning and data, Stats Insider has simulated the outcome of Giants vs Lions 10,000 times.

Our proven predictive analytics model gives the Lions a 78% chance of defeating the Giants at Ford Field.

Lions vs Giants: Odds

The latest Bet365 betting odds in Australia for this NFL game at Ford Field are listed below:

• Head to Head: Lions $1.17, Giants $5.50
• Line: Lions -10.5 ($1.91), Giants +10.5 ($1.91)
• Total (Over/Under 49 Points): Over $1.91, Under $1.91

Odds are correct at the time of publication and subject to change.

Looking at the latest head-to-head odds, Bet365 currently has the Lions at $1.17 and the Giants at $5.50.

The Lions are 10.5-point favourites against the Giants, with odds of $1.91 available at Bet365.

For the underdog Giants (+10.5) to cover the line, Bet365 offers odds of $1.91.

The over/under for total points scored is set at 49 with Bet365, which has odds of $1.91 for the over and $1.91 for the under.

According to Stats Insider's analytics model, the Giants (+10.5) are predicted to cover the line 57% of the time, while the 49-point over/under is expected to stay under 59% of the time.

Lions vs Giants: Betting Tips

• Head to Head: NY Giants at $5.50 with Bet365
• Line: Giants +10.5 at $1.91 with Bet365
• Total Points: Under 49 at $1.91 with Bet365

When you see a 🔥, you know you've found one of Stats Insider's best tips of the day across all sports.

Our Lions vs Giants best bets are based on market-leading modelling and betting intelligence to help you place smarter bets with your chosen online bookie.

While the Lions have a higher chance of winning the game, betting on the Giants to win is our preferred option because of the 3.5% edge found when comparing our data-led probabilities to the odds currently on offer.

Taking advantage of the edges seen on Stats Insider is crucial to achieving long-term profitability.

Lions vs Giants: Prediction

Stats Insider's predicted final score for Lions vs Giants at Ford Field in Week 12 is the Lions winning 27-18.

This prediction is based on each team's average score following 10,000 game simulations.

Stats Insider provides full betting coverage of the Detroit vs NY Giants game in Week 12, including data-driven predictions and the best betting tips.

Our model updates regularly, so bookmark this page for the latest betting tips before the Detroit vs NY Giants game.

As always, see Stats Insider's Best Bets to get the best tips for every NFL game, plus predictions for a wide range of other sports.

Lions vs Giants: Week 12 Essential Details

The NFL Week 12 match-up between the Lions and Giants at Ford Field is scheduled to start at 5:00am AEDT on Monday, November 24.

• Teams: Detroit Lions vs New York Giants
• Date: Monday 24 November 2025
• Time: 5:00am AEDT
• Venue: Ford Field

All dates and times mentioned in this article are in Australian Eastern Daylight Time (AEDT), unless otherwise stated.

Conclusion

Our Detroit vs NY Giants predictions are based on 10,000 data-driven simulations of the game, all curated by our team of expert data scientists and analysts. We use the latest in predictive analytics technology and machine learning to ensure our NFL tips are trustworthy and reliable, giving you the knowledge you need to make informed decisions with confidence.

If you decide to use our NFL predictions for betting purposes, it's vital that you gamble responsibly and manage your finances effectively. For free and confidential support, call 1800 858 858 or visit gamblinghelponline.org.au.

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