Knicks vs Cavaliers Prediction and NBA Tips - 22 May 2026
Last updated: May 22, 2026, 12:09AM | Published: May 21, 2026, 2:00PM
The New York Knicks will take on the Cleveland Cavaliers in Game 2 of the 2026 NBA Eastern Conference Finals at Madison Square Garden on Friday, starting at 10:00am AEST.
Led by the likes of Jalen Brunson, Karl-Anthony Towns and OG Anunoby, the Knicks are looking to overcome a Cavaliers side that includes Donovan Mitchell, James Harden and Evan Mobley.
This article features Stats Insider's best betting tips for the Knicks vs Cavaliers game, plus the latest betting odds.
Who Will Win?
Using trusted machine learning and data, Stats Insider has simulated the result of Friday's New York vs Cleveland NBA Playoffs game 10,000 times.
Our proven predictive analytics model currently gives the Knicks a 70% chance of defeating the Cavaliers in Game 2 of the 2026 Eastern Conference Finals.
Knicks vs Cavaliers: Game 2 Odds
The latest betting odds in Australia for Friday's NBA game at Madison Square Garden are listed below:
- Head to Head: Knicks $1.50, Cavaliers $2.65
- Line: Knicks -5.5 ($1.91), Cavaliers +5.5 ($1.91)
- Total (Over/Under 215.5 Points): Over $1.91, Under $1.91
Odds are correct at the time of publication and subject to change.
Looking at the latest head-to-head odds, the bookmakers currently have the Knicks at $1.50 and the Cavaliers at $2.65.
The Knicks are listed as 5.5-point favourites against the Cavaliers, with odds of $1.91 available at Bet365.
For the underdog Cavaliers (+5.5) to cover the line, Bet365 offers odds of $1.91.
The over/under for total points scored is set at 215.5 with Bet365, which has odds of $1.91 for the over and $1.91 for the under.
According to Stats Insider's analytics model, the Knicks (-5.5) are predicted to cover the line 51% of the time, while the 215.5-point over/under is expected to go over 51% of the time.
Knicks vs Cavaliers: Betting Tips
- Head to Head: New York at $1.50 with Bet365
- Line: Knicks -5.5 at $1.91 with Bet365
- Total Points: Over 215.5 at $1.91 with Bet365
Our Knicks vs Cavaliers predictions are based on detailed simulations and betting experience to help you place more informed bets with your chosen online bookie.
Knicks vs Cavaliers: Prediction
Stats Insider's predicted final score for Knicks vs Cavaliers in Game 2 of the 2026 NBA Eastern Conference Finals on Friday is the Knicks winning 110-105.
This prediction is based on each team's average score from 10,000 game simulations.
Stats Insider provides full coverage of the New York vs Cleveland game on Friday, including data-driven predictions and live win probabilitiestips.
For more detailed information on this matchup, check out Dimers' Knicks vs Cavaliers prediction, put together by experts in the US.
Remember, our model updates frequently, so keep checking this article for the latest betting predictions before the New York vs Cleveland match-up.
As always, see our Best Bets to get betting tips on every NBA game, plus predictions for a wide range of other sports.
Knicks vs Cavaliers: Essential Details
The NBA game between the Knicks and Cavaliers in the NBA Eastern Conference Finals is scheduled to tip off at 10:00am AEST on Friday.
- Teams: New York Knicks vs Cleveland Cavaliers
- Date: Friday 22 May 2026
- Time: 10:00am AEST
- Venue: Madison Square Garden
All dates and times mentioned in this article are in Australian Eastern Standard Time (AEST), unless otherwise stated.
Conclusion
Our New York vs Cleveland predictions have been made after running 10,000 data-driven simulations of the game, carefully curated by our team of skilled data scientists and analysts. We use the latest in predictive analytics technology and machine learning to ensure our NBA tips are trustworthy and reliable, giving you the confidence to make informed decisions.
If you choose to use our predictions for betting purposes, it's crucial that you gamble responsibly and manage your finances effectively. For free and confidential support, call 1800 858 858 or visit gamblinghelponline.org.au.
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