Knicks vs Cavaliers Prediction and NBA Tips - 22 May 2026

The New York Knicks will sqaure off with the Cleveland Cavaliers in Game 2 of the 2026 NBA Eastern Conference Finals at Madison Square Garden on Friday, commencing at 10:00am AEST.

With the likes of Jalen Brunson, Karl-Anthony Towns and OG Anunoby, the Knicks are looking to overcome a Cavaliers side that includes Donovan Mitchell, James Harden and Evan Mobley.

This article features Stats Insider's prediction and tips for the Knicks vs Cavaliers game, along with the latest betting odds.

Who Will Win?

Based on trusted machine learning and data, Stats Insider has simulated the result of Friday's New York vs Cleveland NBA Playoffs match-up 10,000 times.

Our independent predictive analytics model currently gives the Knicks a 70% chance of winning against the Cavaliers in Game 2 of the 2026 Eastern Conference Finals.

Knicks vs Cavaliers: Game 2 Odds

The latest betting odds in Australia for Friday's NBA game at Madison Square Garden are shown here:

• Head to Head: Knicks $1.45, Cavaliers $2.80
• Line: Knicks -5.5 ($1.91), Cavaliers +5.5 ($1.91)
• Total (Over/Under 214.5 Points): Over $1.91, Under $1.91

Odds are correct at the time of publication and subject to change.

Looking at the latest head-to-head odds, the bookmakers currently have the Knicks at $1.45 and the Cavaliers at $2.80.

The Knicks are 5.5-point favourites against the Cavaliers, with odds of $1.91 available at Bet365.

For the underdog Cavaliers (+5.5) to cover the line, Bet365 offers odds of $1.91.

The over/under for total points scored is set at 214.5 with Bet365, which has odds of $1.91 for the over and $1.91 for the under.

According to Stats Insider's analytics model, the Knicks (-5.5) are predicted to cover the line 51% of the time, while the 214.5-point over/under is expected to go over 52% of the time.

Knicks vs Cavaliers: Betting Tips

• Head to Head: New York at $1.45 with Bet365
• Line: Knicks -5.5 at $1.91 with Bet365
• Total Points: Over 214.5 at $1.91 with Bet365

Today's Knicks vs Cavaliers predictions are based on world-class simulations and wagering intelligence to provide you with the best possible advice around the clock.

Knicks vs Cavaliers: Prediction

Stats Insider's predicted final score for Knicks vs Cavaliers in Game 2 of the 2026 NBA Eastern Conference Finals this Friday is the Knicks winning 110-105.

This prediction is based on each team's average score from 10,000 game simulations.

Stats Insider provides full coverage of the New York vs Cleveland game on Friday, including data-driven predictions and live win probabilitiestips.

Our model updates frequently, so refresh this article for the latest betting analysis before the New York vs Cleveland match-up.

As always, see Stats Insider's Best Bets to get betting tips on every NBA game, as well as predictions for a wide range of other sports.

Knicks vs Cavaliers: Essential Details

The NBA match-up between the Knicks and Cavaliers in the NBA Eastern Conference Finals is scheduled to begin at 10:00am AEST on Friday.

• Teams: New York Knicks vs Cleveland Cavaliers
• Date: Friday 22 May 2026
• Time: 10:00am AEST
• Venue: Madison Square Garden

All dates and times mentioned in this article are in Australian Eastern Standard Time (AEST), unless otherwise stated.

Conclusion

Our New York vs Cleveland predictions are based on 10,000 data-driven simulations of the game, carefully curated by our team of experienced data scientists and analysts. We use cutting-edge technology and machine learning to ensure our NBA tips are trustworthy and reliable, giving you the confidence to make informed decisions.

If you decide to use our NBA predictions for betting purposes, it's important to gamble responsibly and keep track of your money. For free and confidential support, call 1800 858 858 or visit gamblinghelponline.org.au.

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