Jaguars vs Panthers Prediction and Preview - NFL Week 1, 2025
Last updated: Aug 20, 2025, 1:14PM | Published: Aug 19, 2025, 4:15PM
The Jacksonville Jaguars will face the Carolina Panthers in NFL Week 1 action at EverBank Stadium on Monday, September 8, beginning at 3:00am AEST.
This article features Stats Insider's best betting tips for the Jaguars vs Panthers game, along with the latest betting odds in Australia.
Who Will Win?
Utilising advanced computer power and data, Stats Insider has simulated the result of Panthers vs Jaguars 10,000 times.
Our leading predictive analytics model gives the Jaguars a 58% chance of winning against the Panthers in Week 1 of the NFL season.
Jaguars vs Panthers: Odds
The latest Bet365 betting odds in Australia for this NFL game at EverBank Stadium are shown below:
- Head to Head: Jaguars $1.64, Panthers $2.30
- Line: Jaguars -3 ($1.91), Panthers +3 ($1.91)
- Total (Over/Under 46 Points): Over $1.91, Under $1.91
Odds are correct at the time of publication and subject to change.
Looking at the latest head-to-head odds, Bet365 currently has the Jaguars at $1.64 and the Panthers at $2.30.
The Jaguars are listed as 3-point favourites against the Panthers, with odds of $1.91 available at Bet365.
For the underdog Panthers (+3) to cover the line, Bet365 offers odds of $1.91.
The over/under for total points scored is set at 46 with Bet365, which has odds of $1.91 for the over and $1.91 for the under.
According to Stats Insider's model, the Panthers (+3) are predicted to cover the line 58% of the time, while the 46-point over/under is expected to stay under 52% of the time.
Jaguars vs Panthers: Best Bets
- Head to Head: Carolina at $2.30 with Bet365
- Line: Panthers +3 at $1.91 with Bet365
- Total Points: Under 46 at $1.91 with Bet365
If you see a 🔥, you know it's one of Stats Insider's best bets for today across all sports.
Stats Insider's Jaguars vs Panthers best bets are based on detailed simulations and betting expertise to help you place smarter bets with your chosen online bookie.
While the Jaguars have a higher chance of winning the game, betting on the Panthers to win is our preferred option due to the edge found when comparing our data-led probabilities to the odds currently on offer.
Taking advantage of the edges published on Stats Insider is pivotal to being a profitable punter in the long run.
Jaguars vs Panthers: Prediction
Stats Insider's predicted final score for Jaguars vs Panthers at EverBank Stadium in Week 1 is the Jaguars winning 23-21.
This prediction is based on each team's average score following 10,000 game simulations.
Stats Insider provides full coverage of the Jacksonville vs Carolina game in Week 1, including data-driven predictions and computer tips.
18+. Odds correct at time of publishing and subject to change.Our model updates frequently, so refresh this page for the latest betting analysis before the Jacksonville vs Carolina game.
As always, see Stats Insider's Best Bets for betting tips on every NFL game, as well as predictions for a wide range of other sports.
Jaguars vs Panthers: Week 1 Essential Details
The NFL Week 1 match-up between the Jaguars and Panthers at EverBank Stadium is scheduled to commence at 3:00am AEST on Monday, September 8.
- Teams: Jacksonville Jaguars vs Carolina Panthers
- Date: Monday 8 September 2025
- Time: 3:00am AEST
- Venue: EverBank Stadium
All dates and times mentioned in this article are in Australian Eastern Standard Time (AEST), unless otherwise stated.
Conclusion
Our Jacksonville vs Carolina predictions are the result of 10,000 data-driven simulations of the game, all curated by our team of skilled data scientists and analysts. We use cutting-edge technology and machine learning to ensure our NFL tips are accurate and reliable, giving you the knowledge you need to make informed decisions with confidence.
If you choose to use our predictions for betting purposes, it's important that you gamble responsibly and know when to stop. For free and confidential support, call 1800 858 858 or visit gamblinghelponline.org.au.
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