Jaguars vs Chiefs Prediction and Preview - NFL Week 5, 2025
Last updated: Oct 3, 2025, 8:15PM | Published: Sep 30, 2025, 6:55AM
The Jacksonville Jaguars will face the Kansas City Chiefs in NFL Week 5 action at EverBank Stadium on Tuesday, beginning at 11:15am AEDT.
This article features Stats Insider's prediction and tips for the Jaguars vs Chiefs game, plus the latest betting odds and touchdown scorer tips.
Who Will Win?
Using advanced computer power and data, Stats Insider has simulated the outcome of Tuesday's Jacksonville vs Kansas City NFL match-up 10,000 times.
Our leading predictive analytics model currently gives the Chiefs a 61% chance of defeating the Jaguars at EverBank Stadium.
Jaguars vs Chiefs: Odds
The current Bet365 betting odds in Australia for Tuesday's NFL game at EverBank Stadium are shown below:
- Head to Head: Jaguars $2.55, Chiefs $1.54
- Line: Jaguars +3.5 ($1.91), Chiefs -3.5 ($1.91)
- Total (Over/Under 46 Points): Over $1.91, Under $1.91
Odds are correct at the time of publication and subject to change.
Looking at the latest head-to-head odds, Bet365 currently has the Jaguars at $2.55 and the Chiefs at $1.54.
The Jaguars are listed as 3.5-point underdogs against the Chiefs, with odds of $1.91 available at Bet365.
For the favourite Chiefs (-3.5) to cover the line, Bet365 offers odds of $1.91.
The over/under for total points scored is set at 46 with Bet365, which has odds of $1.91 for the over and $1.91 for the under.
According to Stats Insider's analytics model, the Jaguars (+3.5) are predicted to cover the line 57% of the time, while the 46-point over/under is expected to go over 51% of the time.
Jaguars vs Chiefs: Betting Tips
- Head to Head: Jacksonville at $2.55 with Bet365
- Line: Jaguars +3.5 at $1.91 with Bet365
- Total Points: Over 46 at $1.91 with Bet365
If you see a 🔥, that means it's one of Stats Insider's best tips of the day across all sports.
Our Jaguars vs Chiefs betting tips are based on complex simulations and gambling expertise to help you place smarter bets with your chosen online bookie.
While the Chiefs have a higher chance of winning the game, betting on the Jaguars to win is our recommended option because of the edge identified when comparing our data-led probabilities to the odds currently on offer.
Taking advantage of the edges seen here at Stats Insider is one of the keys to being profitable in the long run.
Jaguars vs Chiefs: Prediction
Stats Insider's predicted final score for Jaguars vs Chiefs at EverBank Stadium in Week 5 is the Chiefs winning 24-21.
This prediction is based on each team's average score from 10,000 game simulations.
Stats Insider provides full betting coverage of the Jacksonville vs Kansas City game in Week 5, including data-driven predictions and live win probabilitiestips.
18+. Odds correct at time of publishing and subject to change.Jaguars vs Chiefs: TD Scorer Tips
Who will score an anytime touchdown in Jaguars vs Chiefs? The latest data is in.
According to Stats Insider, Jacksonville's Travis Etienne is the most likely player to score the first TD in Jaguars vs Chiefs.
Etienne has a 9.0% chance of getting in for six first at EverBank Stadium, while the Jaguars RB has a 39.2% chance of reaching the end zone at any point during the game.
Scroll down for the complete list of first touchdown scorer and anytime touchdown scorer probabilities.
First Touchdown Scorer Tips
Jaguars First TD Tips
- Travis Etienne: 9.0% probability
- Brian Thomas: 7.1% probability
- Travis Hunter: 5.4% probability
- Bhayshul Tuten: 4.5% probability
- Brenton Strange: 4.1% probability
Chiefs First TD Tips
- Xavier Worthy: 7.9% probability
- Kareem Hunt: 6.8% probability
- Travis Kelce: 6.1% probability
- Hollywood Brown: 5.8% probability
- Isiah Pacheco: 5.4% probability
Anytime Touchdown Scorer Tips
Jaguars Anytime TD Tips
- Travis Etienne: 39.2% probability
- Brian Thomas: 32.6% probability
- Travis Hunter: 26.0% probability
- Bhayshul Tuten: 21.9% probability
- Brenton Strange: 20.4% probability
Chiefs Anytime TD Tips
- Xavier Worthy: 36.1% probability
- Kareem Hunt: 31.7% probability
- Travis Kelce: 29.1% probability
- Hollywood Brown: 28.0% probability
- Isiah Pacheco: 26.2% probability
Jaguars-Chiefs Projected Player Stats
Of the starting quarterbacks, the Jaguars' Trevor Lawrence is projected for 228 passing yards. The Chiefs' Patrick Mahomes is expected to throw for 255 yards.
Jaguars Starting QB
- Trevor Lawrence: 228 projected passing yards
Chiefs Starting QB
- Patrick Mahomes: 255 projected passing yards
Jaguars Rushing Yards
- Travis Etienne: 64 projected yards
- Bhayshul Tuten: 22 projected yards
- Trevor Lawrence: 13 projected yards
Chiefs Rushing Yards
- Isiah Pacheco: 33 projected yards
- Kareem Hunt: 31 projected yards
- Patrick Mahomes: 25 projected yards
Jaguars Receiving Yards
- Brian Thomas: 61 projected yards
- Brenton Strange: 37 projected yards
- Travis Hunter: 34 projected yards
- Dyami Brown: 30 projected yards
- Parker Washington: 23 projected yards
Chiefs Receiving Yards
- Xavier Worthy: 62 projected yards
- Hollywood Brown: 43 projected yards
- Travis Kelce: 43 projected yards
- JuJu Smith-Schuster: 30 projected yards
- Tyquan Thornton: 20 projected yards
Remember, our model updates frequently, so refresh this article for the latest betting tips before the Jacksonville vs Kansas City game.
As always, see Stats Insider's Best Bets for betting tips for every NFL game, plus predictions for a wide range of other sports.
Jaguars vs Chiefs: Week 5 Essential Details
The NFL Week 5 match-up between the Jaguars and Chiefs at EverBank Stadium is scheduled to begin at 11:15am AEDT on Tuesday.
- Teams: Jacksonville Jaguars vs Kansas City Chiefs
- Date: Tuesday 7 October 2025
- Time: 11:15am AEDT
- Venue: EverBank Stadium
All dates and times in this article are in Australian Eastern Daylight Time (AEDT), unless otherwise stated.
Conclusion
Our Jacksonville vs Kansas City predictions have been made thanks to 10,000 data-driven simulations of the game, all curated by our team of expert data scientists and analysts. We use cutting-edge technology and machine learning to ensure our NFL tips are trustworthy and reliable, giving you the confidence to make informed decisions.
If you decide to use our predictions for betting purposes, it's crucial to gamble responsibly and know when to stop. For free and confidential support, call 1800 858 858 or visit gamblinghelponline.org.au.
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