Jaguars vs Chiefs Prediction and Preview - NFL Week 5, 2025
Last updated: Sep 30, 2025, 6:52AM | Published: Sep 30, 2025, 4:00AM
The Jacksonville Jaguars will face the Kansas City Chiefs in NFL Week 5 action at EverBank Stadium on Tuesday, October 7, starting at 11:15am AEDT.
This article features Stats Insider's best betting tips for the Jaguars vs Chiefs game, as well as the latest betting odds and touchdown scorer tips.
Who Will Win?
Using advanced machine learning and data, Stats Insider has simulated the outcome of Chiefs vs Jaguars 10,000 times.
Our independent predictive analytics model currently gives the Chiefs a 60% chance of winning against the Jaguars in Week 5 of the NFL season.
Jaguars vs Chiefs: Odds
The latest Bet365 betting odds in Australia for this NFL game at EverBank Stadium are listed below:
- Head to Head: Jaguars $2.55, Chiefs $1.54
- Line: Jaguars +3.5 ($1.91), Chiefs -3.5 ($1.91)
- Total (Over/Under 45.5 Points): Over $1.91, Under $1.91
Odds are correct at the time of publication and subject to change.
Looking at the latest head-to-head odds, Bet365 currently has the Jaguars at $2.55 and the Chiefs at $1.54.
The Jaguars are 3.5-point underdogs against the Chiefs, with odds of $1.91 available at Bet365.
For the favourite Chiefs (-3.5) to cover the line, Bet365 offers odds of $1.91.
The over/under for total points scored is set at 45.5 with Bet365, which has odds of $1.91 for the over and $1.91 for the under.
According to Stats Insider's analytics model, the Jaguars (+3.5) are predicted to cover the line 57% of the time, while the 45.5-point over/under is expected to is considered an equal 50-50 chance of hitting.
Jaguars vs Chiefs: Betting Tips
- Head to Head: Jacksonville at $2.55 with Bet365
- Line: Jaguars +3.5 at $1.91 with Bet365
- Total Points: Under 45.5 at $1.91 with Bet365
When you see a 🔥, that means you've found one of Stats Insider's best tips for today across all sports.
Our Jaguars vs Chiefs betting tips are based on market-leading modelling and wagering experience to bring you the best possible advice 24/7.
While the Chiefs have a higher chance of winning the game, betting on the Jaguars to win is our preferred option because of the edge identified when comparing our data-led probabilities to the odds currently available.
Taking advantage of the edges seen on Stats Insider is pivotal to being profitable in the long run.
Jaguars vs Chiefs: Prediction
Stats Insider's predicted final score for Jaguars vs Chiefs at EverBank Stadium in Week 5 is the Chiefs winning 23-21.
This prediction is based on each team's average score following 10,000 game simulations.
Stats Insider provides full betting coverage of the Jacksonville vs Kansas City game in Week 5, including data-driven predictions and live win probabilitiestips.
18+. Odds correct at time of publishing and subject to change.Jaguars vs Chiefs: TD Scorer Tips
Who will score the first touchdown in Jaguars vs Chiefs? The latest data is in.
According to Stats Insider, Kansas City's Kareem Hunt is the most likely player to score the first TD in Jaguars vs Chiefs.
Hunt has an 8.7% chance of getting in for six first at EverBank Stadium, while the Chiefs RB has a 37.3% chance of registering an anytime touchdown.
Scroll down for our complete list of first touchdown scorer and anytime touchdown scorer probabilities.
First Touchdown Scorer Tips
Jaguars First TD Tips
- Travis Etienne: 8.1% probability
- Brian Thomas: 7.7% probability
- Travis Hunter: 6.0% probability
- Bhayshul Tuten: 5.3% probability
- Brenton Strange: 3.9% probability
Chiefs First TD Tips
- Kareem Hunt: 8.7% probability
- Xavier Worthy: 8.7% probability
- Hollywood Brown: 6.0% probability
- Isiah Pacheco: 5.6% probability
- Travis Kelce: 5.3% probability
Anytime Touchdown Scorer Tips
Jaguars Anytime TD Tips
- Travis Etienne: 34.3% probability
- Brian Thomas: 32.9% probability
- Travis Hunter: 26.8% probability
- Bhayshul Tuten: 24.1% probability
- Brenton Strange: 18.4% probability
Chiefs Anytime TD Tips
- Kareem Hunt: 37.3% probability
- Xavier Worthy: 37.3% probability
- Hollywood Brown: 27.5% probability
- Isiah Pacheco: 26.1% probability
- Travis Kelce: 24.9% probability
Jaguars-Chiefs Projected Player Stats
Of the starting quarterbacks, the Jaguars' Trevor Lawrence is projected for 245 passing yards, while the Chiefs' Patrick Mahomes is expected to throw for 238 yards.
Jaguars Starting QB
- Trevor Lawrence: 245 projected passing yards
Chiefs Starting QB
- Patrick Mahomes: 238 projected passing yards
Jaguars Rushing Yards
- Travis Etienne: 59 projected yards
- Bhayshul Tuten: 22 projected yards
- Trevor Lawrence: 14 projected yards
Chiefs Rushing Yards
- Isiah Pacheco: 33 projected yards
- Kareem Hunt: 29 projected yards
- Patrick Mahomes: 24 projected yards
Jaguars Receiving Yards
- Brian Thomas: 60 projected yards
- Brenton Strange: 36 projected yards
- Travis Hunter: 36 projected yards
- Dyami Brown: 30 projected yards
- Parker Washington: 23 projected yards
Chiefs Receiving Yards
- Xavier Worthy: 51 projected yards
- Hollywood Brown: 37 projected yards
- Travis Kelce: 35 projected yards
- JuJu Smith-Schuster: 19 projected yards
- Jalen Royals: 16 projected yards
Our model updates frequently, so keep checking this article for the latest betting tips before the Jacksonville vs Kansas City game.
As always, see Stats Insider's Best Bets to get betting tips on every NFL game, plus predictions for a wide range of other sports.
Jaguars vs Chiefs: Week 5 Essential Details
The NFL Week 5 game between the Jaguars and Chiefs at EverBank Stadium is scheduled to start at 11:15am AEDT on Tuesday, October 7.
- Teams: Jacksonville Jaguars vs Kansas City Chiefs
- Date: Tuesday 7 October 2025
- Time: 11:15am AEDT
- Venue: EverBank Stadium
All dates and times in this article are in Australian Eastern Daylight Time (AEDT), unless otherwise stated.
Conclusion
Our Jacksonville vs Kansas City predictions have been made thanks to 10,000 data-driven simulations of the game, all curated by our team of expert data scientists and analysts. We use the latest in predictive analytics technology and machine learning to ensure our NFL tips are trustworthy and reliable, giving you the knowledge you need to make informed decisions with confidence.
If you decide to use our NFL predictions for betting purposes, it's crucial that you gamble responsibly and know when to stop. For free and confidential support, call 1800 858 858 or visit gamblinghelponline.org.au.
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