Guardians vs White Sox Prediction and MLB Tips - 14 September 2025
Last updated: Sep 13, 2025, 4:01AM | Published: Sep 13, 2025, 1:29AM
The Cleveland Guardians will face the Chicago White Sox in MLB action at Progressive Field on Sunday, starting at 8:10am AEST.
Parker Messick (2-0, 1.93 ERA) will start on the mound for the Guardians, while the White Sox will counter with Davis Martin (6-9, 4.03 ERA).
This article features Stats Insider's best betting tips for the Guardians vs White Sox game, along with the latest betting odds in Australia.
Who Will Win?
Based on trusted machine learning and data, Stats Insider has simulated the outcome of Sunday's Cleveland vs White Sox MLB match-up 10,000 times.
Our independent predictive analytics model gives the Guardians a 60% chance of winning against the White Sox at Progressive Field.
Guardians vs White Sox: Odds
The latest betting odds in Australia for Sunday's MLB game at Progressive Field are listed here:
- Head to Head: Guardians $1.60, White Sox $2.41
- Line: Guardians -1.5 ($2.29), White Sox +1.5 ($1.65)
- Total (Over/Under 7.778 Runs): Over $1.91, Under $1.91
Odds are correct at the time of publication and subject to change.
Looking at the latest head-to-head odds, the bookmakers currently have the Guardians at $1.60 and the White Sox at $2.41.
The Guardians are 1.5-run favourites against the White Sox, with odds of $2.29 available at TAB.
For the underdog White Sox (+1.5) to cover the line, TAB offers odds of $1.65.
The over/under for total runs scored is set at 7.778 with TAB, which has odds of $1.91 for the over and $1.91 for the under.
According to Stats Insider's analytics model, the White Sox (+1.5) are predicted to cover the line 60% of the time, while the 7.778-run over/under is expected to go over 51% of the time.
Guardians vs White Sox: Betting Tips
- Head to Head: White Sox at $2.41 with TAB
- Line: White Sox +1.5 at $1.65 with TAB
- Total Runs: Over 7.778 at $1.91 with TAB
Today's Guardians vs White Sox best bets are based on complex simulations and betting intelligence to provide you with the best possible advice 24/7.
While the Guardians have a higher chance of winning the game, betting on the White Sox to win is our recommended option due to the edge found when comparing our data-led probabilities to the odds currently available.
Taking advantage of the edges published on Stats Insider is pivotal to achieving long-term success as a punter.
Guardians vs White Sox: Prediction
Stats Insider provides full betting coverage of the Cleveland vs White Sox game on Sunday, including data-driven predictions and live win probabilitiestips.
Remember, our model updates frequently, so bookmark this article for the latest betting tips before the Cleveland vs White Sox game.
As always, see Stats Insider's Best Bets to get betting tips on every MLB game, as well as predictions for a wide range of other sports.
Guardians vs White Sox: Essential Details
The match-up between the Guardians and White Sox at Progressive Field is scheduled to start at 8:10am AEST on Sunday.
- Teams: Cleveland Guardians vs Chicago White Sox
- Date: Sunday 14 September 2025
- Time: 8:10am AEST
- Venue: Progressive Field
All dates and times mentioned in this article are in Australian Eastern Standard Time (AEST), unless otherwise stated.
Conclusion
Our Cleveland vs White Sox predictions are the result of 10,000 data-driven simulations of the game, all curated by our team of expert data scientists and analysts. We use cutting-edge technology and machine learning to ensure our MLB tips are trustworthy and reliable, giving you the confidence to make informed decisions.
If you decide to use our MLB predictions for betting purposes, it's vital that you gamble responsibly and know when to stop. For free and confidential support, call 1800 858 858 or visit gamblinghelponline.org.au.
More on MLB
Stats Insider is your home for betting on the MLB in Australia, with the latest MLB betting news, tips for every MLB game, and futures odds for the MLB.
