Guardians vs White Sox Prediction and MLB Tips - 14 September 2025
Last updated: Sep 13, 2025, 10:09PM | Published: Sep 13, 2025, 1:29AM
The Cleveland Guardians will take on the Chicago White Sox in MLB action at Progressive Field on Sunday, beginning at 8:10am AEST.
The Guardians will have Parker Messick (2-0, 1.93 ERA) start, pitting him against Davis Martin (6-9, 4.03 ERA) for the White Sox.
This article features Stats Insider's prediction and tips for the Guardians vs White Sox game, as well as the latest betting odds in Australia.
Who Will Win?
Based on advanced computer power and data, Stats Insider has simulated the result of Sunday's Cleveland vs White Sox MLB match-up 10,000 times.
Our proven predictive analytics model gives the Guardians a 61% chance of beating the White Sox at Progressive Field.
Guardians vs White Sox: Odds
The latest betting odds in Australia for Sunday's MLB game at Progressive Field are listed here:
- Head to Head: Guardians $1.59, White Sox $2.45
- Line: Guardians -1.5 ($2.25), White Sox +1.5 ($1.67)
- Total (Over/Under 7.5 Runs): Over $1.91, Under $1.91
Odds are correct at the time of publication and subject to change.
Looking at the latest head-to-head odds, the bookmakers currently have the Guardians at $1.59 and the White Sox at $2.45.
The Guardians are listed as 1.5-run favourites against the White Sox, with odds of $2.25 available at TAB.
For the underdog White Sox (+1.5) to cover the line, TAB offers odds of $1.67.
The over/under for total runs scored is set at 7.5 with TAB, which has odds of $1.91 for the over and $1.91 for the under.
According to Stats Insider's analytics model, the White Sox (+1.5) are predicted to cover the line 59% of the time, while the 7.5-run over/under is expected to go over 51% of the time.
Guardians vs White Sox: Best Bets
- Head to Head: Cleveland at $1.59 with TAB
- Line: White Sox +1.5 at $1.67 with TAB
- Total Runs: Under 7.5 at $1.91 with TAB
These Guardians vs White Sox betting tips are based on complex simulations and wagering intelligence to help you place better bets with your chosen online bookie.
Despite the Over being more likely to hit in this game, Under 7.5 is our best bet due to the better odds ($1.91) that are available from TAB.
Guardians vs White Sox: Prediction
Stats Insider provides full coverage of the Cleveland vs White Sox game on Sunday, including data-driven predictions and live win probabilitiestips.
Remember, our model updates frequently, so bookmark this article for the latest betting analysis before the Cleveland vs White Sox match-up.
As always, see Stats Insider's Best Bets for betting tips on every MLB game, plus predictions for a wide range of other sports.
Guardians vs White Sox: Essential Details
The game between the Guardians and White Sox at Progressive Field is scheduled to commence at 8:10am AEST on Sunday.
- Teams: Cleveland Guardians vs Chicago White Sox
- Date: Sunday 14 September 2025
- Time: 8:10am AEST
- Venue: Progressive Field
All dates and times mentioned in this article are in Australian Eastern Standard Time (AEST), unless otherwise stated.
Conclusion
Our Cleveland vs White Sox predictions have been made after running 10,000 data-driven simulations of the game, all curated by our team of skilled data scientists and analysts. We use the latest in predictive analytics technology and machine learning to ensure our MLB tips are trustworthy and reliable, giving you the confidence to make informed decisions.
If you choose to use our predictions for betting purposes, it's crucial to gamble responsibly and know when to stop. For free and confidential support, call 1800 858 858 or visit gamblinghelponline.org.au.
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