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Guardians vs Twins Prediction and MLB Tips - 4 August 2025

The Cleveland Guardians will take on the Minnesota Twins in MLB action at Progressive Field on Monday, commencing at 3:40am AEST.

Joey Cantillo (2-1, 4.14 ERA) will be on the bump for the Guardians, while the Twins are going with José Ureña (0-0, 5.40 ERA).

This article features Stats Insider's top betting tips for the Guardians vs Twins game, as well as the latest betting odds in Australia.

Who Will Win?

Using trusted machine learning and data, Stats Insider has simulated the outcome of Monday's Cleveland vs Minnesota MLB match-up 10,000 times.

Our proven predictive analytics model gives the Guardians a 62% chance of winning against the Twins at Progressive Field.

Guardians vs Twins: Odds

The latest betting odds in Australia for Monday's MLB game at Progressive Field are listed here:

  • Head to Head: Guardians $1.61, Twins $2.40
  • Line: Guardians -1.5 ($2.25), Twins +1.5 ($1.67)
  • Total (Over/Under 8.5 Runs): Over $1.91, Under $1.91

Odds are correct at the time of publication and subject to change.

Looking at the latest head-to-head odds, the bookmakers currently have the Guardians at $1.61 and the Twins at $2.40.

The Guardians are 1.5-run favourites against the Twins, with odds of $2.25 available at TAB.

For the underdog Twins (+1.5) to cover the line, TAB offers odds of $1.67.

The over/under for total runs scored is set at 8.5 with TAB, which has odds of $1.91 for the over and $1.91 for the under.

According to Stats Insider's model, the Twins (+1.5) are predicted to cover the line 56% of the time, while the 8.5-run over/under is expected to stay under 54% of the time.

Guardians vs Twins: Best Bets

  • Head to Head: Cleveland at $1.61 with TAB
  • Line: Guardians -1.5 at $2.25 with TAB
  • Total Runs: Under 8.5 at $1.91 with TAB

These Guardians vs Twins best bets are based on world-class simulations and gambling intelligence to help you place smarter bets with your chosen online bookie.

Although the Twins are more likely to cover the line, our best bet of Guardians -1.5 is based on the probability of that happening, as projected by our predictive analytics model, and the best odds available.

Guardians vs Twins: Prediction

Stats Insider provides full coverage of the Cleveland vs Minnesota game on Monday, including data-driven predictions and live win probabilitiestips.

Remember, our model updates regularly, so refresh this page for the latest betting analysis before the Cleveland vs Minnesota match-up.

As always, see Stats Insider's Best Bets to get betting tips for every MLB game, as well as predictions for a wide range of other sports.

Guardians vs Twins: Essential Details

The match-up between the Guardians and Twins at Progressive Field is scheduled to commence at 3:40am AEST on Monday.

All dates and times mentioned in this article are in Australian Eastern Standard Time (AEST), unless otherwise stated.

Conclusion

Our Cleveland vs Minnesota predictions have been made based on 10,000 data-driven simulations of the game, carefully curated by our team of experienced data scientists and analysts. We use cutting-edge technology and machine learning to ensure our MLB tips are trustworthy and reliable, giving you the confidence to make informed decisions.

If you decide to use our predictions for betting purposes, it's important to gamble responsibly and keep track of your money. For free and confidential support, call 1800 858 858 or visit gamblinghelponline.org.au.

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Stats Insider is your go-to source for betting on the MLB in Australia, with the latest MLB betting news, tips for every MLB game, and futures odds for the MLB.

Stats Insider

Stats Insider, Australia's leading predictive analytics website, offers Australian sports fans innovative tools and content to enhance their enjoyment of major sporting events both domestically and internationally. Our goal is to transform the sports fan experience by providing readily accessible, data-driven content for sports enthusiasts like us.

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