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Guardians vs Tigers Prediction and MLB Tips - 2 October 2025

The Cleveland Guardians will take on the Detroit Tigers in Game of the League Series at Progressive Field on Thursday, commencing at 3:08am AEST.

The Guardians will have Tanner Bibee (0-0, 0.00 ERA) start, while the Tigers will counter with Casey Mize (0-0, 0.00 ERA).

This article features Stats Insider's top betting tips for the Guardians vs Tigers game, along with the latest betting odds in Australia.

Who Will Win?

Utilising trusted machine learning and data, Stats Insider has simulated the result of Thursday's Cleveland vs Detroit MLB game 10,000 times.

Our leading predictive analytics model currently gives the Guardians a 54% chance of beating the Tigers at Progressive Field.

Guardians vs Tigers: Odds

The current betting odds in Australia for Thursday's MLB game at Progressive Field are shown here:

  • Head to Head: Guardians $1.74, Tigers $2.15
  • Line: Guardians -1.5 ($2.70), Tigers +1.5 ($1.49)
  • Total (Over/Under 6.5 Runs): Over $1.91, Under $1.91

Odds are correct at the time of publication and subject to change.

Looking at the latest head-to-head odds, the bookmakers currently have the Guardians at $1.74 and the Tigers at $2.15.

The Guardians are listed as 1.5-run favourites against the Tigers, with odds of $2.70 available at TAB.

For the underdog Tigers (+1.5) to cover the line, TAB offers odds of $1.49.

The over/under for total runs scored is set at 6.5 with TAB, which has odds of $1.91 for the over and $1.91 for the under.

According to Stats Insider's model, the Tigers (+1.5) are predicted to cover the line 65% of the time, while the 6.5-run over/under is expected to go over 65% of the time.

Guardians vs Tigers: Betting Tips

  • Head to Head: Detroit at $2.15 with TAB
  • Line: Tigers +1.5 at $1.49 with TAB
  • Total Runs: Over 6.5 at $1.91 with TAB

Stats Insider's Guardians vs Tigers predictions are based on world-class modelling and betting intelligence to help you place more informed bets with your chosen online bookie.

While the Guardians have a higher chance of winning the game, betting on the Tigers to win is our preferred option because of the 1.6% edge found when comparing our data-driven probabilities to the odds currently available.

Making use of the edges seen here at Stats Insider is pivotal to achieving long-term success as a punter.

Guardians vs Tigers: Prediction

Stats Insider provides full betting coverage of the Cleveland vs Detroit game on Thursday, including data-driven predictions and free betting tips.

Our model updates frequently, so bookmark this article for the latest betting tips before the Cleveland vs Detroit match-up.

As always, see our Best Bets for the best tips for every MLB game, as well as predictions for a wide range of other sports.

Guardians vs Tigers: Essential Details

The game between the Guardians and Tigers at Progressive Field is scheduled to commence at 3:08am AEST on Thursday.

All dates and times mentioned in this article are in Australian Eastern Standard Time (AEST), unless otherwise noted.

Conclusion

Our Cleveland vs Detroit predictions are the result of 10,000 data-driven simulations of the game, carefully curated by our team of skilled data scientists and analysts. We use the latest in predictive analytics technology and machine learning to ensure our MLB tips are trustworthy and reliable, giving you the confidence to make informed decisions.

If you decide to use our MLB predictions for betting purposes, it's vital that you gamble responsibly and keep track of your money. For free and confidential support, call 1800 858 858 or visit gamblinghelponline.org.au.

More on MLB

Stats Insider is your home for betting on the MLB in Australia, with the latest MLB betting news, predictions for every MLB game, and futures probabilities for the MLB.

Stats Insider

Stats Insider, Australia's leading predictive analytics website, offers Australian sports fans innovative tools and content to enhance their enjoyment of major sporting events both domestically and internationally. Our goal is to transform the sports fan experience by providing readily accessible, data-driven content for sports enthusiasts like us.

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