Guardians vs Tigers Prediction and MLB Tips - 1 October 2025
Last updated: Sep 30, 2025, 5:09PM | Published: Sep 30, 2025, 6:55AM
The Cleveland Guardians will face the Detroit Tigers in Game 197 of the American League Division Series at Progressive Field on Wednesday, starting at 3:08am AEST.
The Guardians will have Gavin Williams (0-0, 0.00 ERA) start, while the Tigers are going with Tarik Skubal (0-0, 0.00 ERA).
This article features Stats Insider's best betting tips for the Guardians vs Tigers game, as well as the latest betting odds in Australia.
Who Will Win?
Based on advanced machine learning and data, Stats Insider has simulated the outcome of Wednesday's Cleveland vs Detroit MLB game 10,000 times.
Our leading predictive analytics model currently gives the Tigers a 60% chance of defeating the Guardians at Progressive Field.
Guardians vs Tigers: Odds
The latest betting odds in Australia for Wednesday's MLB game at Progressive Field are listed here:
- Head to Head: Guardians $2.42, Tigers $1.59
- Line: Guardians +1.5 ($1.74), Tigers -1.5 ($2.14)
- Total (Over/Under 6.056 Runs): Over $1.91, Under $1.91
Odds are correct at the time of publication and subject to change.
Looking at the latest head-to-head odds, the bookmakers currently have the Guardians at $2.42 and the Tigers at $1.59.
The Guardians are listed as 1.5-run underdogs against the Tigers, with odds of $1.74 available at TAB.
For the favourite Tigers (-1.5) to cover the line, TAB offers odds of $2.14.
The over/under for total runs scored is set at 6.056 with TAB, which has odds of $1.91 for the over and $1.91 for the under.
According to Stats Insider's model, the Guardians (+1.5) are predicted to cover the line 54% of the time, while the 6.056-run over/under is expected to go over 61% of the time.
Guardians vs Tigers: Best Bets
- Head to Head: Cleveland at $2.42 with TAB
- Line: Tigers -1.5 at $2.14 with TAB
- Total Runs: Over 6.056 at $1.91 with TAB
Today's Guardians vs Tigers predictions are based on detailed modelling and gambling expertise to provide you with the best possible advice around the clock.
And while the Tigers have a higher chance of winning the game, betting on the Guardians to win is our recommended option due to the edge found when comparing our data-driven probabilities to the odds currently available.
Making use of the edges seen here at Stats Insider is one of the keys to being a profitable sports bettor in the long run.
Even though the Guardians are more likely to cover the line, our best bet of Tigers -1.5 is based on the probability of that happening, as suggested by our predictive analytics model, and the top odds available.
Guardians vs Tigers: Prediction
Stats Insider provides full coverage of the Cleveland vs Detroit game on Wednesday, including data-driven predictions and free tips.
Remember, our model updates frequently, so refresh this article for the latest betting tips before the Cleveland vs Detroit match-up.
As always, see Stats Insider's Best Bets for betting tips for every MLB game, plus predictions for a wide range of other sports.
Guardians vs Tigers: Essential Details
The match-up between the Guardians and Tigers at Progressive Field is scheduled to start at 3:08am AEST on Wednesday.
- Teams: Cleveland Guardians vs Detroit Tigers
- Date: Wednesday 1 October 2025
- Time: 3:08am AEST
- Venue: Progressive Field
All dates and times mentioned in this article are in Australian Eastern Standard Time (AEST), unless otherwise noted.
Conclusion
Our Cleveland vs Detroit predictions are based on 10,000 data-driven simulations of the game, all curated by our team of experienced data scientists and analysts. We use the latest in predictive analytics technology and machine learning to ensure our MLB tips are trustworthy and reliable, so that you can make informed decisions with confidence.
If you decide to use our MLB predictions for betting purposes, it's crucial to gamble responsibly and keep track of your money. For free and confidential support, call 1800 858 858 or visit gamblinghelponline.org.au.
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