Guardians vs Tigers Prediction and MLB Tips - 1 October 2025
Last updated: Sep 30, 2025, 6:50AM | Published: Sep 29, 2025, 7:27PM
The Cleveland Guardians will face the Detroit Tigers in Game 197 of the American League Division Series at Progressive Field on Wednesday, beginning at 3:08am AEST.
The Guardians will send Gavin Williams (0-0, 0.00 ERA) to the mound, pitting him against Tarik Skubal (0-0, 0.00 ERA) for the Tigers.
This article features Stats Insider's prediction and tips for the Guardians vs Tigers game, along with the latest betting odds in Australia.
Who Will Win?
Utilising advanced computer power and data, Stats Insider has simulated the result of Wednesday's Cleveland vs Detroit MLB match-up 10,000 times.
Our proven predictive analytics model currently gives the Tigers a 59% chance of beating the Guardians at Progressive Field.
Guardians vs Tigers: Odds
The latest betting odds in Australia for Wednesday's MLB game at Progressive Field are shown below:
- Head to Head: Guardians $2.35, Tigers $1.62
- Line: Guardians +1.5 ($1.72), Tigers -1.5 ($2.20)
- Total (Over/Under 6 Runs): Over $1.91, Under $1.91
Odds are correct at the time of publication and subject to change.
Looking at the latest head-to-head odds, the bookmakers currently have the Guardians at $2.35 and the Tigers at $1.62.
The Guardians are 1.5-run underdogs against the Tigers, with odds of $1.72 available at TAB.
For the favourite Tigers (-1.5) to cover the line, TAB offers odds of $2.20.
The over/under for total runs scored is set at 6 with TAB, which has odds of $1.91 for the over and $1.91 for the under.
According to Stats Insider's analytics model, the Guardians (+1.5) are predicted to cover the line 56% of the time, while the 6-run over/under is expected to go over 63% of the time.
Guardians vs Tigers: Betting Tips
- Head to Head: Cleveland at $2.35 with TAB
- Line: Tigers -1.5 at $2.20 with TAB
- Total Runs: Over 6 at $1.91 with TAB
Stats Insider's Guardians vs Tigers best bets are based on market-leading simulations and wagering expertise to help you place better bets with your chosen online bookie.
And while the Tigers have a higher chance of winning the game, betting on the Guardians to win is our recommended option because of the edge identified when comparing our data-led probabilities to the odds currently available.
Taking advantage of the edges seen here at Stats Insider is one of the keys to being profitable in the long run.
Even though the Guardians are more likely to cover the line, our best bet of Tigers -1.5 is based on the likelihood of that happening, as projected by our predictive analytics model, and the best odds available.
Guardians vs Tigers: Prediction
Stats Insider provides full coverage of the Cleveland vs Detroit game on Wednesday, including data-driven predictions and expert tips.
Our model updates regularly, so bookmark this article for the latest betting predictions before the Cleveland vs Detroit match-up.
As always, see our Best Bets for betting tips on every MLB game, as well as predictions for a wide range of other sports.
Guardians vs Tigers: Essential Details
The match-up between the Guardians and Tigers at Progressive Field is scheduled to start at 3:08am AEST on Wednesday.
- Teams: Cleveland Guardians vs Detroit Tigers
- Date: Wednesday 1 October 2025
- Time: 3:08am AEST
- Venue: Progressive Field
All dates and times mentioned in this article are in Australian Eastern Standard Time (AEST), unless otherwise stated.
Conclusion
Our Cleveland vs Detroit predictions have been made based on 10,000 data-driven simulations of the game, all curated by our team of skilled data scientists and analysts. We use the latest in predictive analytics technology and machine learning to ensure our MLB tips are trustworthy and reliable, so that you can make informed decisions with confidence.
If you choose to use our predictions for betting purposes, it's vital to gamble responsibly and know when to stop. For free and confidential support, call 1800 858 858 or visit gamblinghelponline.org.au.
More on MLB
Stats Insider is your home for betting on the MLB in Australia, with the latest MLB betting news, tips for every MLB game, and futures odds for the MLB.
