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Guardians vs Orioles Prediction and MLB Tips - 25 July 2025

The Cleveland Guardians will face the Baltimore Orioles in MLB action at Progressive Field on Friday, beginning at 3:10am AEST.

Logan Allen (6-8, 4.06 ERA) will be on the bump for the Guardians, up against Charlie Morton (5-8, 5.58 ERA) for the Orioles.

This article features Stats Insider's top betting tips for the Guardians vs Orioles game, as well as the latest betting odds in Australia.

Who Will Win?

Utilising advanced computer power and data, Stats Insider has simulated the outcome of Friday's Cleveland vs Baltimore MLB game 10,000 times.

Our independent predictive analytics model gives the Guardians a 53% chance of winning against the Orioles at Progressive Field.

Guardians vs Orioles: Odds

The latest betting odds in Australia for Friday's MLB game at Progressive Field are shown below:

  • Head to Head: Guardians $1.80, Orioles $2.05
  • Line: Guardians -1.5 ($2.70), Orioles +1.5 ($1.49)
  • Total (Over/Under 9 Runs): Over $1.91, Under $1.91

Odds are correct at the time of publication and subject to change.

Looking at the latest head-to-head odds, the bookmakers currently have the Guardians at $1.80 and the Orioles at $2.05.

The Guardians are listed as 1.5-run favourites against the Orioles, with odds of $2.70 available at TAB.

For the underdog Orioles (+1.5) to cover the line, TAB offers odds of $1.49.

The over/under for total runs scored is set at 9 with TAB, which has odds of $1.91 for the over and $1.91 for the under.

According to Stats Insider's analytics model, the Orioles (+1.5) are predicted to cover the line 66% of the time, while the 9-run over/under is expected to stay under 57% of the time.

Guardians vs Orioles: Best Bets

  • Head to Head: Baltimore at $2.05 with TAB
  • Line: Orioles +1.5 at $1.49 with TAB
  • Total Runs: Under 9 at $1.91 with TAB

These Guardians vs Orioles betting tips are based on complex simulations and betting intelligence to give you the best possible advice every time.

While the Guardians have a higher chance of winning the game, betting on the Orioles to win is our recommended option because of the edge identified when comparing our data-driven probabilities to the odds currently available.

Making use of the edges seen here at Stats Insider is crucial to being profitable in the long run.

Guardians vs Orioles: Prediction

Stats Insider provides full coverage of the Cleveland vs Baltimore game on Friday, including data-driven predictions and expert tips.

Our model updates regularly, so refresh this article for the latest betting predictions before the Cleveland vs Baltimore game.

As always, see our Best Bets to get the best tips on every MLB game, plus predictions for a wide range of other sports.

Guardians vs Orioles: Essential Details

The game between the Guardians and Orioles at Progressive Field is scheduled to begin at 3:10am AEST on Friday.

All dates and times in this article are in Australian Eastern Standard Time (AEST), unless otherwise stated.

Conclusion

Our Cleveland vs Baltimore predictions have been made thanks to 10,000 data-driven simulations of the game, carefully curated by our team of skilled data scientists and analysts. We use the latest in predictive analytics technology and machine learning to ensure our MLB tips are accurate and reliable, giving you the confidence to make informed decisions.

If you decide to use our predictions for betting purposes, it's important to gamble responsibly and know when to stop. For free and confidential support, call 1800 858 858 or visit gamblinghelponline.org.au.

More on MLB

Stats Insider is your home for betting on the MLB in Australia, with the latest MLB betting news, predictions for every MLB game, and futures odds for the MLB.

Stats Insider

Stats Insider, Australia's leading predictive analytics website, offers Australian sports fans innovative tools and content to enhance their enjoyment of major sporting events both domestically and internationally. Our goal is to transform the sports fan experience by providing readily accessible, data-driven content for sports enthusiasts like us.

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