Guardians vs Orioles Prediction and MLB Tips - 23 July 2025

The Cleveland Guardians will sqaure off with the Baltimore Orioles in MLB action at Progressive Field on Wednesday, starting at 8:40am AEST.

Joey Cantillo (1-0, 4.17 ERA) will start on the mound for the Guardians, while the Orioles are going with Brandon Young (0-4, 7.52 ERA).

This article features Stats Insider's prediction and tips for the Guardians vs Orioles game, plus the latest betting odds in Australia.

Who Will Win?

Based on trusted computer power and data, Stats Insider has simulated the result of Wednesday's Cleveland vs Baltimore MLB game 10,000 times.

Our independent predictive analytics model currently gives the Guardians a 59% chance of defeating the Orioles at Progressive Field.

Guardians vs Orioles: Odds

The latest betting odds in Australia for Wednesday's MLB game at Progressive Field are listed below:

• Head to Head: Guardians $1.62, Orioles $2.35
• Line: Guardians -1.5 ($2.35), Orioles +1.5 ($1.62)
• Total (Over/Under 8 Runs): Over $1.91, Under $1.91

Odds are correct at the time of publication and subject to change.

Looking at the latest head-to-head odds, the bookmakers currently have the Guardians at $1.62 and the Orioles at $2.35.

The Guardians are 1.5-run favourites against the Orioles, with odds of $2.35 available at TAB.

For the underdog Orioles (+1.5) to cover the line, TAB offers odds of $1.62.

The over/under for total runs scored is set at 8 with TAB, which has odds of $1.91 for the over and $1.91 for the under.

According to Stats Insider's analytics model, the Orioles (+1.5) are predicted to cover the line 61% of the time, while the 8-run over/under is expected to stay under 52% of the time.

Guardians vs Orioles: Betting Tips

• Head to Head: Baltimore at $2.35 with TAB
• Line: Orioles +1.5 at $1.62 with TAB
• Total Runs: Under 8 at $1.91 with TAB

These Guardians vs Orioles predictions are based on world-class modelling and betting experience to help you place more informed bets with your chosen online bookie.

While the Guardians have a higher chance of winning the game, betting on the Orioles to win is our recommended option because of the edge identified when comparing our data-driven probabilities to the odds currently on offer.

Taking advantage of the edges seen on Stats Insider is one of the keys to being profitable in the long run.

Guardians vs Orioles: Prediction

Stats Insider provides full betting coverage of the Cleveland vs Baltimore game on Wednesday, including data-driven predictions and live win probabilitiestips.

Remember, our model updates regularly, so keep checking this article for the latest betting tips before the Cleveland vs Baltimore game.

As always, see Stats Insider's Best Bets for betting tips on every MLB game, as well as predictions for a wide range of other sports.

Guardians vs Orioles: Essential Details

The match-up between the Guardians and Orioles at Progressive Field is scheduled to begin at 8:40am AEST on Wednesday.

• Teams: Cleveland Guardians vs Baltimore Orioles
• Date: Wednesday 23 July 2025
• Time: 8:40am AEST
• Venue: Progressive Field

All dates and times in this article are in Australian Eastern Standard Time (AEST), unless otherwise noted.

Conclusion

Our Cleveland vs Baltimore predictions have been made after running 10,000 data-driven simulations of the game, all curated by our team of experienced data scientists and analysts. We use cutting-edge technology and machine learning to ensure our MLB tips are accurate and reliable, so that you can make informed decisions with confidence.

If you choose to use our predictions for betting purposes, it's vital that you gamble responsibly and manage your finances effectively. For free and confidential support, call 1800 858 858 or visit gamblinghelponline.org.au.

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