Giants vs Cubs Prediction and MLB Tips - 27 August 2025
Last updated: Aug 27, 2025, 1:46AM | Published: Aug 25, 2025, 6:34PM
The San Francisco Giants will face the Chicago Cubs in MLB action at Oracle Park on Wednesday, starting at 11:45am AEST.
Justin Verlander (1-10, 4.64 ERA) will be on the bump for the Giants, pitting him against Matthew Boyd (12-6, 2.62 ERA) for the Cubs.
This article features Stats Insider's best betting tips for the Giants vs Cubs game, along with the latest betting odds in Australia.
Who Will Win?
Based on advanced computer power and data, Stats Insider has simulated the result of Wednesday's San Francisco vs Cubs MLB match-up 10,000 times.
Our independent predictive analytics model currently gives the Cubs a 57% chance of defeating the Giants at Oracle Park.
Giants vs Cubs: Odds
The current betting odds in Australia for Wednesday's MLB game at Oracle Park are listed here:
- Head to Head: Giants $2.25, Cubs $1.67
- Line: Giants +1.5 ($1.72), Cubs -1.5 ($2.20)
- Total (Over/Under 7.5 Runs): Over $1.91, Under $1.91
Odds are correct at the time of publication and subject to change.
Looking at the latest head-to-head odds, the bookmakers currently have the Giants at $2.25 and the Cubs at $1.67.
The Giants are listed as 1.5-run underdogs against the Cubs, with odds of $1.72 available at TAB.
For the favourite Cubs (-1.5) to cover the line, TAB offers odds of $2.20.
The over/under for total runs scored is set at 7.5 with TAB, which has odds of $1.91 for the over and $1.91 for the under.
According to Stats Insider's model, the Giants (+1.5) are predicted to cover the line 57% of the time, while the 7.5-run over/under is expected to stay under 51% of the time.
Giants vs Cubs: Best Bets
- Head to Head: San Francisco at $2.25 with TAB
- Line: Giants +1.5 at $1.72 with TAB
- Total Runs: Under 7.5 at $1.91 with TAB
These Giants vs Cubs predictions are based on market-leading modelling and betting expertise to help you place more informed bets with your chosen online bookie.
While the Cubs have a higher chance of winning the game, betting on the Giants to win is our preferred option due to the edge identified when comparing our data-led probabilities to the odds currently available.
Making use of the edges published here at Stats Insider is crucial to achieving long-term success as a bettor.
Giants vs Cubs: Prediction
Stats Insider provides full coverage of the San Francisco vs Cubs game on Wednesday, including data-driven predictions and free betting tips.
Our model updates frequently, so refresh this article for the latest betting tips before the San Francisco vs Cubs match-up.
As always, see our Best Bets for betting tips on every MLB game, plus predictions for a wide range of other sports.
Giants vs Cubs: Essential Details
The match-up between the Giants and Cubs at Oracle Park is scheduled to commence at 11:45am AEST on Wednesday.
- Teams: San Francisco Giants vs Chicago Cubs
- Date: Wednesday 27 August 2025
- Time: 11:45am AEST
- Venue: Oracle Park
All dates and times in this article are in Australian Eastern Standard Time (AEST), unless otherwise stated.
Conclusion
Our San Francisco vs Cubs predictions have been made after running 10,000 data-driven simulations of the game, all curated by our team of expert data scientists and analysts. We use the latest in predictive analytics technology and machine learning to ensure our MLB tips are trustworthy and reliable, so that you can make informed decisions with confidence.
If you choose to use our MLB predictions for betting purposes, it's crucial to gamble responsibly and manage your finances effectively. For free and confidential support, call 1800 858 858 or visit gamblinghelponline.org.au.
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