Giants vs Chiefs Prediction and Preview - NFL Week 3, 2025
Last updated: Sep 15, 2025, 8:31AM | Published: Sep 15, 2025, 4:01AM
The New York Giants will sqaure off with the favoured Kansas City Chiefs in NFL Week 3 action at MetLife Stadium on Monday, September 22, starting at 10:20am AEST.
This article features Stats Insider's prediction and tips for the Giants vs Chiefs game, along with the latest betting odds in Australia.
Who Will Win?
Based on trusted computer power and data, Stats Insider has simulated the result of Chiefs vs Giants 10,000 times.
Our leading predictive analytics model currently gives the Chiefs a 71% chance of defeating the Giants at MetLife Stadium.
Giants vs Chiefs: Odds
The latest Bet365 betting odds in Australia for this NFL game at MetLife Stadium are listed below:
- Head to Head: Giants $3.10, Chiefs $1.38
- Line: Giants +5.5 ($1.91), Chiefs -5.5 ($1.91)
- Total (Over/Under 43.5 Points): Over $1.91, Under $1.91
Odds are correct at the time of publication and subject to change.
Looking at the latest head-to-head odds, Bet365 currently has the Giants at $3.10 and the Chiefs at $1.38.
The Giants are 5.5-point underdogs against the Chiefs, with odds of $1.91 available at Bet365.
For the favourite Chiefs (-5.5) to cover the line, Bet365 offers odds of $1.91.
The over/under for total points scored is set at 43.5 with Bet365, which has odds of $1.91 for the over and $1.91 for the under.
According to Stats Insider's model, the Giants (+5.5) are predicted to cover the line 51% of the time, while the 43.5-point over/under is expected to is considered an equal 50-50 chance of hitting.
Giants vs Chiefs: Best Bets
- Head to Head: Kansas City at $1.38 with Bet365
- Line: Giants +5.5 at $1.91 with Bet365
- Total Points: Under 43.5 at $1.91 with Bet365
These Giants vs Chiefs predictions are based on detailed modelling and gambling experience to help you place better bets with your chosen online bookie.
Giants vs Chiefs: Prediction
Stats Insider's predicted final score for Giants vs Chiefs at MetLife Stadium in Week 3 is the Chiefs winning 24-19.
This prediction is based on each team's average score from 10,000 game simulations.
Stats Insider provides full coverage of the NY Giants vs Kansas City game in Week 3, including data-driven predictions and expert tips.
18+. Odds correct at time of publishing and subject to change.Our model updates regularly, so refresh this page for the latest betting tips before the NY Giants vs Kansas City match-up.
As always, see our Best Bets for betting tips on every NFL game, as well as predictions for a wide range of other sports.
Giants vs Chiefs: Week 3 Essential Details
The NFL Week 3 game between the Giants and Chiefs at MetLife Stadium is scheduled to commence at 10:20am AEST on Monday, September 22.
- Teams: New York Giants vs Kansas City Chiefs
- Date: Monday 22 September 2025
- Time: 10:20am AEST
- Venue: MetLife Stadium
All dates and times mentioned in this article are in Australian Eastern Standard Time (AEST), unless otherwise noted.
Conclusion
Our NY Giants vs Kansas City predictions have been made after running 10,000 data-driven simulations of the game, all curated by our team of expert data scientists and analysts. We use cutting-edge technology and machine learning to ensure our NFL tips are trustworthy and reliable, giving you the confidence to make informed decisions.
If you decide to use our predictions for betting purposes, it's important that you gamble responsibly and know when to stop. For free and confidential support, call 1800 858 858 or visit gamblinghelponline.org.au.
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