Giants vs 49ers Prediction and Preview - NFL Week 9, 2025
Last updated: Oct 28, 2025, 8:56PM | Published: Oct 26, 2025, 4:01AM
The New York Giants will face the San Francisco 49ers in NFL Week 9 action at MetLife Stadium on Monday, commencing at 5:00am AEDT.
This article features Stats Insider's prediction and tips for the Giants vs 49ers game, along with the latest betting odds and touchdown scorer tips.
Who Will Win?
Utilising advanced machine learning and data, Stats Insider has simulated the outcome of Monday's NY Giants vs San Francisco NFL game 10,000 times.
Our independent predictive analytics model gives the 49ers a 58% chance of beating the Giants in Week 9 of the NFL season.
Giants vs 49ers: Odds
The current Bet365 betting odds in Australia for Monday's NFL game at MetLife Stadium are shown below:
- Head to Head: Giants $2.30, 49ers $1.64
- Line: Giants +2.5 ($1.91), 49ers -2.5 ($1.91)
- Total (Over/Under 48.5 Points): Over $1.91, Under $1.91
Odds are correct at the time of publication and subject to change.
Looking at the latest head-to-head odds, Bet365 currently has the Giants at $2.30 and the 49ers at $1.64.
The Giants are listed as 2.5-point underdogs against the 49ers, with odds of $1.91 available at Bet365.
For the favourite 49ers (-2.5) to cover the line, Bet365 offers odds of $1.91.
The over/under for total points scored is set at 48.5 with Bet365, which has odds of $1.91 for the over and $1.91 for the under.
According to Stats Insider's analytics model, the bookies have got it right and both the Giants and the 49ers have a 50% chance of covering the line.
The 48.5-point over/under is expected to is also considered an equal 50-50 chance of hitting.
Giants vs 49ers: Betting Tips
- Head to Head: NY Giants at $2.30 with Bet365
- Line: 49ers -2.5 at $1.91 with Bet365
- Total Points: Under 48.5 at $1.91 with Bet365
Stats Insider's Giants vs 49ers best bets are based on detailed simulations and betting intelligence to give you the best possible advice every day of the year.
While the 49ers have a higher chance of winning the game, betting on the Giants to win is our preferred option because of the edge identified when comparing our data-led probabilities to the odds currently available.
Making use of the edges published on Stats Insider is one of the keys to achieving long-term success as a bettor.
Giants vs 49ers: Prediction
Stats Insider's predicted final score for Giants vs 49ers at MetLife Stadium in Week 9 is the 49ers winning 25-22.
This prediction is based on each team's average score from 10,000 game simulations.
Stats Insider provides full coverage of the NY Giants vs San Francisco game in Week 9, including data-driven predictions and live updatestips.
18+. Odds correct at time of publishing and subject to change.Giants vs 49ers: TD Scorer Tips
Who will score an anytime touchdown in Giants vs 49ers? The data is in.
According to Stats Insider, San Francisco's Christian McCaffrey is the most likely player to score the first touchdown in Giants vs 49ers.
McCaffrey has a 16.7% chance of scoring the first TD at MetLife Stadium, while the 49ers RB has a 63.3% chance of reaching the end zone at any point during the game.
Scroll down for our full list of first touchdown scorer and anytime touchdown scorer probabilities.
First Touchdown Scorer Tips
Giants First TD Tips
- Tyrone Tracy: 8.7% probability
- Wan'Dale Robinson: 8.0% probability
- Jaxson Dart: 5.6% probability
- Theo Johnson: 5.4% probability
- Devin Singletary: 5.1% probability
49ers First TD Tips
- Christian McCaffrey: 16.7% probability
- George Kittle: 7.8% probability
- Jauan Jennings: 6.1% probability
- Ricky Pearsall: 5.5% probability
- Kendrick Bourne: 3.9% probability
Anytime Touchdown Scorer Tips
Giants Anytime TD Tips
- Tyrone Tracy: 40.2% probability
- Wan'Dale Robinson: 37.9% probability
- Jaxson Dart: 28.4% probability
- Theo Johnson: 27.5% probability
- Devin Singletary: 26.1% probability
49ers Anytime TD Tips
- Christian McCaffrey: 63.3% probability
- George Kittle: 37.4% probability
- Jauan Jennings: 30.8% probability
- Ricky Pearsall: 28.0% probability
- Kendrick Bourne: 20.9% probability
Giants-49ers Projected Player Stats
Of the starting quarterbacks, the Giants' Jaxson Dart is projected for 209 passing yards. The 49ers' Brock Purdy is expected to throw for 237 yards.
Giants Starting QB
- Jaxson Dart: 209 projected passing yards
49ers Starting QB
- Brock Purdy: 237 projected passing yards
Giants Rushing Yards
- Tyrone Tracy: 50 projected yards
- Devin Singletary: 27 projected yards
- Jaxson Dart: 25 projected yards
49ers Rushing Yards
- Christian McCaffrey: 82 projected yards
- Brock Purdy: 18 projected yards
- Brian Robinson: 15 projected yards
Giants Receiving Yards
- Wan'Dale Robinson: 54 projected yards
- Darius Slayton: 42 projected yards
- Theo Johnson: 33 projected yards
- Tyrone Tracy: 19 projected yards
- Lil'Jordan Humphrey: 15 projected yards
49ers Receiving Yards
- Jauan Jennings: 49 projected yards
- George Kittle: 47 projected yards
- Ricky Pearsall: 45 projected yards
- Christian McCaffrey: 41 projected yards
- Kendrick Bourne: 31 projected yards
Remember, our model updates regularly, so bookmark this page for the latest betting analysis before the NY Giants vs San Francisco match-up.
As always, see Stats Insider's Best Bets for the best tips on every NFL game, plus predictions for a wide range of other sports.
Giants vs 49ers: Week 9 Essential Details
The NFL Week 9 match-up between the Giants and 49ers at MetLife Stadium is scheduled to commence at 5:00am AEDT on Monday.
- Teams: New York Giants vs San Francisco 49ers
- Date: Monday 3 November 2025
- Time: 5:00am AEDT
- Venue: MetLife Stadium
All dates and times mentioned in this article are in Australian Eastern Daylight Time (AEDT), unless otherwise stated.
Conclusion
Our NY Giants vs San Francisco predictions have been made based on 10,000 data-driven simulations of the game, carefully curated by our team of expert data scientists and analysts. We use the latest in predictive analytics technology and machine learning to ensure our NFL tips are trustworthy and reliable, giving you the confidence to make informed decisions.
If you decide to use our NFL predictions for betting purposes, it's vital to gamble responsibly and manage your finances effectively. For free and confidential support, call 1800 858 858 or visit gamblinghelponline.org.au.
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