Eagles vs 49ers Prediction and Preview - NFL Wild Card Round 2026
Last updated: Jan 7, 2026, 7:55AM | Published: Jan 5, 2026, 11:50AM
The Philadelphia Eagles will sqaure off with the San Francisco 49ers on Wild Card Weekend of the NFL Playoffs at Lincoln Financial Field on Monday, commencing at 8:30am AEDT.
This article features Stats Insider's free betting tips for the Eagles vs 49ers game, plus the latest betting odds and touchdown scorer tips.
Who Will Win?
Based on advanced machine learning and data, Stats Insider has simulated the outcome of Monday's Philadelphia vs San Francisco NFL game 10,000 times.
Our independent predictive analytics model gives the Eagles a 65% chance of beating the 49ers at Lincoln Financial Field.
Eagles vs 49ers: Odds
The latest Bet365 betting odds in Australia for Monday's NFL game at Lincoln Financial Field are shown below:
- Head to Head: Eagles $1.43, 49ers $2.90
- Line: Eagles -4.5 ($1.91), 49ers +4.5 ($1.91)
- Total (Over/Under 44.5 Points): Over $1.91, Under $1.91
Odds are correct at the time of publication and subject to change.
Looking at the latest head-to-head odds, Bet365 currently has the Eagles at $1.43 and the 49ers at $2.90.
The Eagles are 4.5-point favourites against the 49ers, with odds of $1.91 available at Bet365.
For the underdog 49ers (+4.5) to cover the line, Bet365 offers odds of $1.91.
The over/under for total points scored is set at 44.5 with Bet365, which has odds of $1.91 for the over and $1.91 for the under.
According to Stats Insider's model, the 49ers (+4.5) are predicted to cover the line 54% of the time, while the 44.5-point over/under is expected to is considered an equal 50-50 chance of hitting.
Eagles vs 49ers: Best Bets
- Head to Head: San Francisco at $2.90 with Bet365
- Line: 49ers +4.5 at $1.91 with Bet365
- Total Points: Under 44.5 at $1.91 with Bet365
Stats Insider's Eagles vs 49ers predictions are based on detailed simulations and wagering expertise to give you the best possible advice every time.
While the Eagles have a higher chance of winning the game, betting on the 49ers to win is our preferred option because of the 1.0% edge found when comparing our data-led probabilities to the odds currently available.
Making use of the edges seen here at Stats Insider is one of the keys to being profitable in the long run.
Eagles vs 49ers: Prediction
Stats Insider's predicted final score for Eagles vs 49ers at Lincoln Financial Field this Monday is the Eagles winning 24-20.
This prediction is based on each team's average score following 10,000 game simulations.
Stats Insider provides full betting coverage of the Philadelphia vs San Francisco game on Monday, including data-driven predictions and live scorestips.
18+. Odds correct at time of publishing and subject to change.Eagles vs 49ers: TD Scorer Tips
Who will score the first touchdown in Eagles vs 49ers? The data is in.
According to Stats Insider, San Francisco's Christian McCaffrey is the most likely player to score the first touchdown in Eagles vs 49ers.
McCaffrey has a 14.0% chance of getting in for six first at Lincoln Financial Field, while the 49ers RB has a 58.1% chance of reaching the end zone at any point during the game.
Scroll down for our full list of first touchdown scorer and anytime touchdown scorer probabilities.
First Touchdown Scorer Tips
Eagles First TD Tips
- Saquon Barkley: 11.1% probability
- Jalen Hurts: 9.5% probability
- A.J. Brown: 7.9% probability
- DeVonta Smith: 6.7% probability
- Dallas Goedert: 6.5% probability
49ers First TD Tips
- Christian McCaffrey: 14.0% probability
- George Kittle: 6.7% probability
- Jauan Jennings: 5.8% probability
- Ricky Pearsall: 3.8% probability
- Demarcus Robinson: 2.9% probability
Anytime Touchdown Scorer Tips
Eagles Anytime TD Tips
- Saquon Barkley: 47.3% probability
- Jalen Hurts: 42.2% probability
- A.J. Brown: 36.6% probability
- DeVonta Smith: 32.1% probability
- Dallas Goedert: 31.4% probability
49ers Anytime TD Tips
- Christian McCaffrey: 58.1% probability
- George Kittle: 34.2% probability
- Jauan Jennings: 30.3% probability
- Ricky Pearsall: 21.0% probability
- Demarcus Robinson: 16.7% probability
Eagles-49ers Projected Player Stats
Of the starting quarterbacks, the Eagles' Jalen Hurts is projected for 215 passing yards, while the 49ers' Brock Purdy is expected to throw for 231 yards.
Eagles Starting QB
- Jalen Hurts: 215 projected passing yards
49ers Starting QB
- Brock Purdy: 231 projected passing yards
Eagles Rushing Yards
- Saquon Barkley: 80 projected yards
- Jalen Hurts: 33 projected yards
- Tank Bigsby: 14 projected yards
49ers Rushing Yards
- Christian McCaffrey: 67 projected yards
- Brock Purdy: 21 projected yards
- Brian Robinson: 18 projected yards
Eagles Receiving Yards
- A.J. Brown: 70 projected yards
- DeVonta Smith: 59 projected yards
- Dallas Goedert: 42 projected yards
- Saquon Barkley: 18 projected yards
- Jahan Dotson: 14 projected yards
49ers Receiving Yards
- George Kittle: 58 projected yards
- Jauan Jennings: 50 projected yards
- Christian McCaffrey: 44 projected yards
- Ricky Pearsall: 42 projected yards
- Demarcus Robinson: 16 projected yards
Remember, our model updates regularly, so keep checking this article for the latest betting analysis before the Philadelphia vs San Francisco match-up.
As always, see our Best Bets for betting tips for every NFL game, as well as predictions for a wide range of other sports.
Eagles vs 49ers: Essential Details
The game between the Eagles and 49ers at Lincoln Financial Field is scheduled to commence at 8:30am AEDT on Monday.
- Teams: Philadelphia Eagles vs San Francisco 49ers
- Playoff Round: NFL Wild Card Weekend
- Date: Monday 12 January 2026
- Time: 8:30am AEDT
- Venue: Lincoln Financial Field
All dates and times mentioned in this article are in Australian Eastern Daylight Time (AEDT), unless otherwise noted.
Conclusion
Our Philadelphia vs San Francisco predictions have been made after running 10,000 data-driven simulations of the game, all curated by our team of expert data scientists and analysts. We use cutting-edge technology and machine learning to ensure our NFL tips are accurate and reliable, giving you the confidence to make informed decisions.
If you choose to use our NFL predictions for betting purposes, it's crucial to gamble responsibly and know when to stop. For free and confidential support, call 1800 858 858 or visit gamblinghelponline.org.au.
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