Eagles vs 49ers Prediction and Preview - NFL Wild Card Round 2026

The Philadelphia Eagles will face the San Francisco 49ers on Wild Card Weekend of the NFL Playoffs at Lincoln Financial Field on Monday, beginning at 8:30am AEDT.

This article features Stats Insider's prediction and tips for the Eagles vs 49ers game, as well as the latest betting odds and touchdown scorer tips.

Who Will Win?

Using advanced computer power and data, Stats Insider has simulated the result of Monday's Philadelphia vs San Francisco NFL game 10,000 times.

Our independent predictive analytics model currently gives the Eagles a 68% chance of defeating the 49ers at Lincoln Financial Field.

Eagles vs 49ers: Odds

The current Bet365 betting odds in Australia for Monday's NFL game at Lincoln Financial Field are listed below:

• Head to Head: Eagles $1.41, 49ers $3.00
• Line: Eagles -5.5 ($1.91), 49ers +5.5 ($1.91)
• Total (Over/Under 44.5 Points): Over $1.91, Under $1.91

Odds are correct at the time of publication and subject to change.

Looking at the latest head-to-head odds, Bet365 currently has the Eagles at $1.41 and the 49ers at $3.00.

The Eagles are 5.5-point favourites against the 49ers, with odds of $1.91 available at Bet365.

For the underdog 49ers (+5.5) to cover the line, Bet365 offers odds of $1.91.

The over/under for total points scored is set at 44.5 with Bet365, which has odds of $1.91 for the over and $1.91 for the under.

According to Stats Insider's model, the 49ers (+5.5) are predicted to cover the line 54% of the time, while the 44.5-point over/under is expected to is considered an equal 50-50 chance of hitting.

Eagles vs 49ers: Betting Tips

• Head to Head: San Francisco at $3.00 with Bet365
• Line: 49ers +5.5 at $1.91 with Bet365
• Total Points: Under 44.5 at $1.91 with Bet365

These Eagles vs 49ers best bets are based on world-class modelling and gambling experience to help you place smarter bets with your chosen online bookie.

While the Eagles have a higher chance of winning the game, betting on the 49ers to win is our recommended option due to the edge identified when comparing our data-led probabilities to the odds currently available.

Making use of the edges published on Stats Insider is crucial to achieving long-term profitability.

Eagles vs 49ers: Prediction

Stats Insider's predicted final score for Eagles vs 49ers at Lincoln Financial Field on Monday is the Eagles winning 24-19.

This prediction is based on each team's average score from 10,000 game simulations.

Stats Insider provides full coverage of the Philadelphia vs San Francisco game on Monday, including data-driven predictions and expert tips.

Get expert analysis from the US with Dimers' in-depth Eagles vs 49ers prediction.

18+. Odds correct at time of publishing and subject to change.

Eagles vs 49ers: TD Scorer Tips

Who will score the first touchdown in Eagles vs 49ers? The latest data is in.

According to Stats Insider, San Francisco's Christian McCaffrey is the most likely player to score the first touchdown in Eagles vs 49ers.

McCaffrey has a 14.4% chance of scoring the first TD at Lincoln Financial Field, while the 49ers RB has a 57.8% chance of reaching the end zone at any point in the game.

Scroll down for the full list of first touchdown scorer and anytime touchdown scorer probabilities.

First Touchdown Scorer Tips

Eagles First TD Tips

• Saquon Barkley: 12.1% probability
• Jalen Hurts: 10.0% probability
• A.J. Brown: 8.4% probability
• Dallas Goedert: 7.4% probability
• DeVonta Smith: 6.9% probability

49ers First TD Tips

• Christian McCaffrey: 14.4% probability
• George Kittle: 7.0% probability
• Jauan Jennings: 6.2% probability
• Demarcus Robinson: 3.1% probability
• Brock Purdy: 2.8% probability

Anytime Touchdown Scorer Tips

Eagles Anytime TD Tips

• Saquon Barkley: 48.0% probability
• Jalen Hurts: 41.9% probability
• A.J. Brown: 36.6% probability
• Dallas Goedert: 32.9% probability
• DeVonta Smith: 31.2% probability

49ers Anytime TD Tips

• Christian McCaffrey: 57.8% probability
• George Kittle: 34.1% probability
• Jauan Jennings: 30.8% probability
• Demarcus Robinson: 16.9% probability
• Brock Purdy: 15.3% probability

Eagles-49ers Projected Player Stats

Of the starting quarterbacks, the Eagles' Jalen Hurts is projected for 214 passing yards. The 49ers' Brock Purdy is expected to throw for 228 yards.

Eagles Starting QB

• Jalen Hurts: 214 projected passing yards

49ers Starting QB

• Brock Purdy: 228 projected passing yards

Eagles Rushing Yards

• Saquon Barkley: 81 projected yards
• Jalen Hurts: 33 projected yards
• Tank Bigsby: 12 projected yards

49ers Rushing Yards

• Christian McCaffrey: 69 projected yards
• Brock Purdy: 21 projected yards
• Brian Robinson: 17 projected yards

Eagles Receiving Yards

• A.J. Brown: 71 projected yards
• DeVonta Smith: 59 projected yards
• Dallas Goedert: 42 projected yards
• Saquon Barkley: 19 projected yards
• Jahan Dotson: 15 projected yards

49ers Receiving Yards

• George Kittle: 58 projected yards
• Jauan Jennings: 50 projected yards
• Christian McCaffrey: 44 projected yards
• Demarcus Robinson: 28 projected yards
• Kendrick Bourne: 22 projected yards

Remember, our model updates frequently, so refresh this article for the latest betting tips before the Philadelphia vs San Francisco match-up.

As always, see our Best Bets to get betting tips for every NFL game, plus predictions for a wide range of other sports.

Eagles vs 49ers: Essential Details

The match-up between the Eagles and 49ers at Lincoln Financial Field is scheduled to start at 8:30am AEDT on Monday.

• Teams: Philadelphia Eagles vs San Francisco 49ers
• Playoff Round: NFL Wild Card Weekend
• Date: Monday 12 January 2026
• Time: 8:30am AEDT
• Venue: Lincoln Financial Field

All dates and times mentioned in this article are in Australian Eastern Daylight Time (AEDT), unless otherwise stated.

Conclusion

Our Philadelphia vs San Francisco predictions have been made based on 10,000 data-driven simulations of the game, all curated by our team of expert data scientists and analysts. We use the latest in predictive analytics technology and machine learning to ensure our NFL tips are trustworthy and reliable, giving you the confidence to make informed decisions.

If you choose to use our predictions for betting purposes, it's crucial to gamble responsibly and keep track of your money. For free and confidential support, call 1800 858 858 or visit gamblinghelponline.org.au.

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