Dodgers vs Giants Prediction and MLB Tips - 22 September 2025
Last updated: Sep 21, 2025, 8:10PM | Published: Sep 21, 2025, 12:29AM
The Los Angeles Dodgers will sqaure off with the San Francisco Giants in Game of the League Series at Dodger Stadium on Monday, starting at 6:10am AEST.
The Dodgers will have Emmet Sheehan (6-3, 3.17 ERA) start, pitting him against Trevor McDonald (0-0, 9.00 ERA) for the Giants.
This article features Stats Insider's prediction and tips for the Dodgers vs Giants game, as well as the latest betting odds in Australia.
Who Will Win?
Using trusted computer power and data, Stats Insider has simulated the outcome of Monday's LA Dodgers vs San Francisco MLB game 10,000 times.
Our proven predictive analytics model gives the Dodgers a 66% chance of defeating the Giants at Dodger Stadium.
Dodgers vs Giants: Odds
The current betting odds in Australia for Monday's MLB game at Dodger Stadium are listed here:
- Head to Head: Dodgers $1.46, Giants $2.76
- Line: Dodgers -1.5 ($1.93), Giants +1.5 ($1.89)
- Total (Over/Under 9.2 Runs): Over $1.91, Under $1.91
Odds are correct at the time of publication and subject to change.
Looking at the latest head-to-head odds, the bookmakers currently have the Dodgers at $1.46 and the Giants at $2.76.
The Dodgers are listed as 1.5-run favourites against the Giants, with odds of $1.93 available at TAB.
For the underdog Giants (+1.5) to cover the line, TAB offers odds of $1.89.
The over/under for total runs scored is set at 9.2 with TAB, which has odds of $1.91 for the over and $1.91 for the under.
According to Stats Insider's analytics model, the bookmakers have got it right and both the Dodgers and the Giants have a 50% chance of covering the line.
The 9.2-run over/under is expected to go over 51% of the time.
Dodgers vs Giants: Betting Tips
- Head to Head: LA Dodgers at $1.46 with TAB
- Line: Dodgers -1.5 at $1.93 with TAB
- Total Runs: Over 9.2 at $1.91 with TAB
Today's Dodgers vs Giants betting tips are based on detailed simulations and gambling experience to help you place more informed bets with your chosen online bookie.
Dodgers vs Giants: Prediction
Stats Insider provides full betting coverage of the LA Dodgers vs San Francisco game on Monday, including data-driven predictions and free tips.
Our model updates frequently, so bookmark this page for the latest betting analysis before the LA Dodgers vs San Francisco game.
As always, see Stats Insider's Best Bets to get the best tips on every MLB game, plus predictions for a wide range of other sports.
Dodgers vs Giants: Essential Details
The game between the Dodgers and Giants at Dodger Stadium is scheduled to begin at 6:10am AEST on Monday.
- Teams: Los Angeles Dodgers vs San Francisco Giants
- Date: Monday 22 September 2025
- Time: 6:10am AEST
- Venue: Dodger Stadium
All dates and times mentioned in this article are in Australian Eastern Standard Time (AEST), unless otherwise noted.
Conclusion
Our LA Dodgers vs San Francisco predictions are based on 10,000 data-driven simulations of the game, all curated by our team of expert data scientists and analysts. We use the latest in predictive analytics technology and machine learning to ensure our MLB tips are accurate and reliable, giving you the knowledge you need to make informed decisions with confidence.
If you choose to use our predictions for betting purposes, it's crucial that you gamble responsibly and know when to stop. For free and confidential support, call 1800 858 858 or visit gamblinghelponline.org.au.
More on MLB
Stats Insider is your home for betting on the MLB in Australia, with the latest MLB betting news, predictions for every MLB game, and futures probabilities for the MLB.