Diamondbacks vs Reds Prediction and MLB Tips - 22 August 2026
Last updated: Aug 22, 2026, 1:44AM | Published: Aug 20, 2026, 7:36PM
The Arizona Diamondbacks will take on the Cincinnati Reds in MLB action at Chase Field on Saturday, beginning at 11:40am AEST.
Eduardo Rodriguez (12-4, 2.71 ERA) will start on the mound for the Diamondbacks, while the Reds will counter with Nick Lodolo (3-2, 4.52 ERA).
This article features Stats Insider's best betting tips for the Diamondbacks vs Reds game, plus the latest betting odds in Australia.
Who Will Win?
Based on trusted machine learning and data, Stats Insider has simulated the outcome of Saturday's Arizona vs Cincinnati MLB match-up 10,000 times.
Our proven predictive analytics model currently gives the Diamondbacks a 57% chance of defeating the Reds at Chase Field.
Diamondbacks vs Reds: Odds
The latest betting odds in Australia for Saturday's MLB game at Chase Field are listed below:
- Head to Head: Diamondbacks $1.71, Reds $2.31
- Line: Diamondbacks -1.5 ($2.40), Reds +1.5 ($1.61)
- Total (Over/Under 8.5 Runs): Over $1.91, Under $1.91
Odds are correct at the time of publication and subject to change.
Looking at the latest head-to-head odds, the bookmakers currently have the Diamondbacks at $1.71 and the Reds at $2.31.
The Diamondbacks are 1.5-run favourites against the Reds, with odds of $2.40 available at TAB.
For the underdog Reds (+1.5) to cover the line, TAB offers odds of $1.61.
The over/under for total runs scored is set at 8.5 with TAB, which has odds of $1.91 for the over and $1.91 for the under.
According to Stats Insider's analytics model, the Reds (+1.5) are predicted to cover the line 59% of the time, while the 8.5-run over/under is expected to go over 58% of the time.
Diamondbacks vs Reds: Betting Tips
- Head to Head: Cincinnati at $2.31 with TAB
- Line: Diamondbacks -1.5 at $2.40 with TAB
- Total Runs: Over 8.5 at $1.91 with TAB
Today's Diamondbacks vs Reds best bets are based on market-leading simulations and wagering intelligence to provide you with the best possible advice every day of the year.
And while the Diamondbacks have a higher chance of winning the game, betting on the Reds to win is our recommended option due to the edge found when comparing our data-driven probabilities to the odds currently on offer.
Making use of the edges seen on Stats Insider is one of the keys to being a profitable punter in the long run.
Although the Reds are more likely to cover the line, our best bet of Diamondbacks -1.5 is based on the probability of that happening, as suggested by our predictive analytics model, and the best odds available.
Diamondbacks vs Reds: Prediction
Stats Insider provides full coverage of the Arizona vs Cincinnati game on Saturday, including data-driven predictions and live win probabilitiestips.
Remember, our model updates regularly, so refresh this article for the latest betting predictions before the Arizona vs Cincinnati game.
As always, see Stats Insider's Best Bets to get betting tips for every MLB game, as well as predictions for a wide range of other sports.
Diamondbacks vs Reds: Essential Details
The match-up between the Diamondbacks and Reds at Chase Field is scheduled to begin at 11:40am AEST on Saturday.
- Teams: Arizona Diamondbacks vs Cincinnati Reds
- Date: Saturday 22 August 2026
- Time: 11:40am AEST
- Venue: Chase Field
All dates and times mentioned in this article are in Australian Eastern Standard Time (AEST), unless otherwise stated.
Conclusion
Our Arizona vs Cincinnati predictions are based on 10,000 data-driven simulations of the game, all curated by our team of expert data scientists and analysts. We use the latest in predictive analytics technology and machine learning to ensure our MLB tips are accurate and reliable, giving you the knowledge you need to make informed decisions with confidence.
If you choose to use our MLB predictions for betting purposes, it's crucial to gamble responsibly and know when to stop. For free and confidential support, call 1800 858 858 or visit gamblinghelponline.org.au.
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