Diamondbacks vs Phillies Prediction and MLB Tips - 22 September 2025

The Arizona Diamondbacks will take on the Philadelphia Phillies in Game of the League Series at Chase Field on Monday, commencing at 6:10am AEST.

The Diamondbacks will send Eduardo Rodriguez (8-8, 5.12 ERA) to the mound, while the Phillies will counter with Ranger Suárez (12-6, 2.84 ERA).

This article features Stats Insider's prediction and tips for the Diamondbacks vs Phillies game, as well as the latest betting odds in Australia.

Who Will Win?

Using advanced machine learning and data, Stats Insider has simulated the result of Monday's Arizona vs Philadelphia MLB match-up 10,000 times.

Our independent predictive analytics model currently gives the Phillies a 54% chance of beating the Diamondbacks at Chase Field.

Diamondbacks vs Phillies: Odds

The current betting odds in Australia for Monday's MLB game at Chase Field are listed below:

• Head to Head: Diamondbacks $2.10, Phillies $1.77
• Line: Diamondbacks +1.5 ($1.67), Phillies -1.5 ($2.25)
• Total (Over/Under 8.5 Runs): Over $1.91, Under $1.91

Odds are correct at the time of publication and subject to change.

Looking at the latest head-to-head odds, the bookmakers currently have the Diamondbacks at $2.10 and the Phillies at $1.77.

The Diamondbacks are 1.5-run underdogs against the Phillies, with odds of $1.67 available at TAB.

For the favourite Phillies (-1.5) to cover the line, TAB offers odds of $2.25.

The over/under for total runs scored is set at 8.5 with TAB, which has odds of $1.91 for the over and $1.91 for the under.

According to Stats Insider's analytics model, the Diamondbacks (+1.5) are predicted to cover the line 59% of the time, while the 8.5-run over/under is expected to go over 54% of the time.

Diamondbacks vs Phillies: Best Bets

• Head to Head: Arizona at $2.10 with TAB
• Line: Diamondbacks +1.5 at $1.67 with TAB
• Total Runs: Over 8.5 at $1.91 with TAB

These Diamondbacks vs Phillies best bets are based on market-leading simulations and gambling expertise to bring you the best possible advice every time.

While the Phillies have a higher chance of winning the game, betting on the Diamondbacks to win is our preferred option because of the edge found when comparing our data-driven probabilities to the odds currently on offer.

Making use of the edges published on Stats Insider is one of the keys to being a profitable sports bettor in the long run.

Diamondbacks vs Phillies: Prediction

Stats Insider provides full betting coverage of the Arizona vs Philadelphia game on Monday, including data-driven predictions and live win probabilitiestips.

Remember, our model updates frequently, so refresh this article for the latest betting tips before the Arizona vs Philadelphia match-up.

As always, see our Best Bets for betting tips for every MLB game, as well as predictions for a wide range of other sports.

Diamondbacks vs Phillies: Essential Details

The match-up between the Diamondbacks and Phillies at Chase Field is scheduled to commence at 6:10am AEST on Monday.

• Teams: Arizona Diamondbacks vs Philadelphia Phillies
• Date: Monday 22 September 2025
• Time: 6:10am AEST
• Venue: Chase Field

All dates and times mentioned in this article are in Australian Eastern Standard Time (AEST), unless otherwise stated.

Conclusion

Our Arizona vs Philadelphia predictions have been made after running 10,000 data-driven simulations of the game, all curated by our team of skilled data scientists and analysts. We use cutting-edge technology and machine learning to ensure our MLB tips are accurate and reliable, giving you the confidence to make informed decisions.

If you choose to use our MLB predictions for betting purposes, it's important that you gamble responsibly and know when to stop. For free and confidential support, call 1800 858 858 or visit gamblinghelponline.org.au.

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