Diamondbacks vs Guardians Prediction and MLB Tips - 20 August 2025
Last updated: Aug 20, 2025, 1:42AM | Published: Aug 19, 2025, 6:16PM
The Arizona Diamondbacks will take on the Cleveland Guardians in MLB action at Chase Field on Wednesday, starting at 11:40am AEST.
Eduardo Rodriguez (5-7, 5.40 ERA) will start for the Diamondbacks, while the Guardians are going with Tanner Bibee (9-9, 4.54 ERA).
This article features Stats Insider's top betting tips for the Diamondbacks vs Guardians game, plus the latest betting odds in Australia.
Who Will Win?
Utilising advanced machine learning and data, Stats Insider has simulated the result of Wednesday's Arizona vs Cleveland MLB match-up 10,000 times.
Our independent predictive analytics model currently gives the Diamondbacks a 54% chance of beating the Guardians at Chase Field.
Diamondbacks vs Guardians: Odds
The current betting odds in Australia for Wednesday's MLB game at Chase Field are listed here:
- Head to Head: Diamondbacks $1.83, Guardians $2.00
- Line: Diamondbacks -1.5 ($2.70), Guardians +1.5 ($1.49)
- Total (Over/Under 8.5 Runs): Over $1.91, Under $1.91
Odds are correct at the time of publication and subject to change.
Looking at the latest head-to-head odds, the bookmakers currently have the Diamondbacks at $1.83 and the Guardians at $2.00.
The Diamondbacks are 1.5-run favourites against the Guardians, with odds of $2.70 available at TAB.
For the underdog Guardians (+1.5) to cover the line, TAB offers odds of $1.49.
The over/under for total runs scored is set at 8.5 with TAB, which has odds of $1.91 for the over and $1.91 for the under.
According to Stats Insider's model, the Guardians (+1.5) are predicted to cover the line 64% of the time, while the 8.5-run over/under is expected to is considered an equal 50-50 chance of hitting.
Diamondbacks vs Guardians: Betting Tips
- Head to Head: Arizona at $1.83 with TAB
- Line: Diamondbacks -1.5 at $2.70 with TAB
- Total Runs: Under 8.5 at $1.91 with TAB
Today's Diamondbacks vs Guardians best bets are based on market-leading simulations and gambling experience to help you place smarter bets with your chosen online bookie.
Although the Guardians are more likely to cover the line, our best bet of Diamondbacks -1.5 is based on the probability of that happening, as suggested by our predictive analytics model, and the top odds available.
Diamondbacks vs Guardians: Prediction
Stats Insider provides full betting coverage of the Arizona vs Cleveland game on Wednesday, including data-driven predictions and live win probabilitiestips.
Our model updates regularly, so bookmark this page for the latest betting tips before the Arizona vs Cleveland match-up.
As always, see Stats Insider's Best Bets to get the best tips on every MLB game, as well as predictions for a wide range of other sports.
Diamondbacks vs Guardians: Essential Details
The match-up between the Diamondbacks and Guardians at Chase Field is scheduled to start at 11:40am AEST on Wednesday.
- Teams: Arizona Diamondbacks vs Cleveland Guardians
- Date: Wednesday 20 August 2025
- Time: 11:40am AEST
- Venue: Chase Field
All dates and times mentioned in this article are in Australian Eastern Standard Time (AEST), unless otherwise noted.
Conclusion
Our Arizona vs Cleveland predictions are the result of 10,000 data-driven simulations of the game, all curated by our team of expert data scientists and analysts. We use the latest in predictive analytics technology and machine learning to ensure our MLB tips are trustworthy and reliable, giving you the confidence to make informed decisions.
If you decide to use our MLB predictions for betting purposes, it's important that you gamble responsibly and keep track of your money. For free and confidential support, call 1800 858 858 or visit gamblinghelponline.org.au.
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