Diamondbacks vs Cardinals Prediction and MLB Tips - 21 July 2025
Last updated: Jul 20, 2025, 8:10PM | Published: Jul 19, 2025, 7:48PM
The Arizona Diamondbacks will face the St. Louis Cardinals in MLB action at Chase Field on Monday, starting at 6:10am AEST.
Merrill Kelly (8-5, 3.34 ERA) will start on the mound for the Diamondbacks, pitting him against Miles Mikolas (5-6, 4.94 ERA) for the Cardinals.
This article features Stats Insider's top betting tips for the Diamondbacks vs Cardinals game, plus the latest betting odds in Australia.
Who Will Win?
Utilising advanced computer power and data, Stats Insider has simulated the outcome of Monday's Arizona vs St. Louis MLB match-up 10,000 times.
Our leading predictive analytics model gives the Diamondbacks a 57% chance of defeating the Cardinals at Chase Field.
Diamondbacks vs Cardinals: Odds
The current betting odds in Australia for Monday's MLB game at Chase Field are shown here:
- Head to Head: Diamondbacks $1.71, Cardinals $2.20
- Line: Diamondbacks -1.5 ($2.45), Cardinals +1.5 ($1.59)
- Total (Over/Under 9 Runs): Over $1.91, Under $1.91
Odds are correct at the time of publication and subject to change.
Looking at the latest head-to-head odds, the bookmakers currently have the Diamondbacks at $1.71 and the Cardinals at $2.20.
The Diamondbacks are listed as 1.5-run favourites against the Cardinals, with odds of $2.45 available at TAB.
For the underdog Cardinals (+1.5) to cover the line, TAB offers odds of $1.59.
The over/under for total runs scored is set at 9 with TAB, which has odds of $1.91 for the over and $1.91 for the under.
According to Stats Insider's analytics model, the Cardinals (+1.5) are predicted to cover the line 60% of the time, while the 9-run over/under is expected to stay under 52% of the time.
Diamondbacks vs Cardinals: Betting Tips
- Head to Head: Arizona at $1.71 with TAB
- Line: Diamondbacks -1.5 at $2.45 with TAB
- Total Runs: Under 9 at $1.91 with TAB
Stats Insider's Diamondbacks vs Cardinals best bets are based on complex modelling and betting expertise to help you place more informed bets with your chosen online bookie.
Even though the Cardinals are more likely to cover the line, our best bet of Diamondbacks -1.5 is based on the chance of that happening, as projected by our predictive analytics model, and the best odds available.
Diamondbacks vs Cardinals: Prediction
Stats Insider provides full betting coverage of the Arizona vs St. Louis game on Monday, including data-driven predictions and free tips.
Our model updates regularly, so keep checking this page for the latest betting analysis before the Arizona vs St. Louis game.
As always, see our Best Bets to get the best tips on every MLB game, as well as predictions for a wide range of other sports.
Diamondbacks vs Cardinals: Essential Details
The match-up between the Diamondbacks and Cardinals at Chase Field is scheduled to commence at 6:10am AEST on Monday.
- Teams: Arizona Diamondbacks vs St. Louis Cardinals
- Date: Monday 21 July 2025
- Time: 6:10am AEST
- Venue: Chase Field
All dates and times in this article are in Australian Eastern Standard Time (AEST), unless otherwise stated.
Conclusion
Our Arizona vs St. Louis predictions have been made after running 10,000 data-driven simulations of the game, all curated by our team of skilled data scientists and analysts. We use cutting-edge technology and machine learning to ensure our MLB tips are accurate and reliable, giving you the knowledge you need to make informed decisions with confidence.
If you decide to use our MLB predictions for betting purposes, it's important that you gamble responsibly and know when to stop. For free and confidential support, call 1800 858 858 or visit gamblinghelponline.org.au.
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