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Cubs vs White Sox Prediction and MLB Tips - 17 May 2025

The Chicago Cubs will face the Chicago White Sox in MLB action at Wrigley Field on Saturday, commencing at 4:20am AEST.

Cade Horton (1-0, 6.75 ERA) will get the ball for the Cubs, pitting him against Shane Smith (1-2, 2.08 ERA) for the White Sox.

This article features Stats Insider's top betting tips for the Cubs vs White Sox game, plus the latest betting odds in Australia.

Who Will Win?

Using trusted computer power and data, Stats Insider has simulated the result of Saturday's Cubs vs White Sox MLB game 10,000 times.

Our leading predictive analytics model gives the Cubs a 66% chance of winning against the White Sox at Wrigley Field.

Cubs vs White Sox: Odds

The latest betting odds in Australia for Saturday's MLB game at Wrigley Field are listed here:

  • Head to Head: Cubs $1.42, White Sox $2.95
  • Line: Cubs -1.5 ($1.88), White Sox +1.5 ($1.95)
  • Total (Over/Under 11.5 Runs): Over $1.91, Under $1.91

Odds are correct at the time of publication and subject to change.

Looking at the latest head-to-head odds, the bookmakers currently have the Cubs at $1.42 and the White Sox at $2.95.

The Cubs are 1.5-run favourites against the White Sox, with odds of $1.88 available at TAB.

For the underdog White Sox (+1.5) to cover the line, TAB offers odds of $1.95.

The over/under for total runs scored is set at 11.5 with TAB, which has odds of $1.91 for the over and $1.91 for the under.

According to Stats Insider's model, the White Sox (+1.5) are predicted to cover the line 52% of the time, while the 11.5-run over/under is expected to stay under 62% of the time.

Cubs vs White Sox: Best Bets

  • Head to Head: White Sox at $2.95 with TAB
  • Line: White Sox +1.5 at $1.95 with TAB
  • Total Runs: Under 11.5 at $1.91 with TAB

These Cubs vs White Sox predictions are based on market-leading simulations and wagering expertise to help you place smarter bets with your chosen online bookie.

While the Cubs have a higher chance of winning the game, betting on the White Sox to win is our preferred option because of the 1.5% edge identified when comparing our data-driven probabilities to the odds currently on offer.

Making use of the edges seen on Stats Insider is one of the keys to being profitable in the long run.

Cubs vs White Sox: Prediction

Stats Insider provides full coverage of the Cubs vs White Sox game on Saturday, including data-driven predictions and the best betting tips.

Remember, our model updates frequently, so bookmark this page for the latest betting tips before the Cubs vs White Sox match-up.

As always, see Stats Insider's Best Bets to get the best tips on every MLB game, as well as predictions for a wide range of other sports.

Cubs vs White Sox: Essential Details

The game between the Cubs and White Sox at Wrigley Field is scheduled to start at 4:20am AEST on Saturday.

All dates and times in this article are in Australian Eastern Standard Time (AEST), unless otherwise stated.

Conclusion

Our Cubs vs White Sox predictions are the result of 10,000 data-driven simulations of the game, carefully curated by our team of skilled data scientists and analysts. We use the latest in predictive analytics technology and machine learning to ensure our MLB tips are trustworthy and reliable, giving you the confidence to make informed decisions.

If you decide to use our MLB predictions for betting purposes, it's important to gamble responsibly and know when to stop. For free and confidential support, call 1800 858 858 or visit gamblinghelponline.org.au.

More on MLB

Stats Insider is your home for betting on the MLB in Australia, with the latest MLB betting news, tips for every MLB game, and futures probabilities for the MLB.

Stats Insider

Stats Insider, Australia's leading predictive analytics website, offers Australian sports fans innovative tools and content to enhance their enjoyment of major sporting events both domestically and internationally. Our goal is to transform the sports fan experience by providing readily accessible, data-driven content for sports enthusiasts like us.

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