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Cubs vs Rays Prediction and MLB Tips - 15 September 2025

The Chicago Cubs will sqaure off with the Tampa Bay Rays in MLB action at Wrigley Field on Monday, starting at 4:20am AEST.

Shota Imanaga (9-7, 3.21 ERA) will start for the Cubs, pitting him against Adrian Houser (8-4, 3.11 ERA) for the Rays.

This article features Stats Insider's prediction and tips for the Cubs vs Rays game, as well as the latest betting odds in Australia.

Who Will Win?

Utilising trusted computer power and data, Stats Insider has simulated the outcome of Monday's Cubs vs Tampa Bay MLB game 10,000 times.

Our proven predictive analytics model currently gives the Cubs a 61% chance of defeating the Rays at Wrigley Field.

Cubs vs Rays: Odds

The latest betting odds in Australia for Monday's MLB game at Wrigley Field are shown below:

  • Head to Head: Cubs $1.61, Rays $2.40
  • Line: Cubs -1.5 ($2.29), Rays +1.5 ($1.65)
  • Total (Over/Under 7.5 Runs): Over $1.91, Under $1.91

Odds are correct at the time of publication and subject to change.

Looking at the latest head-to-head odds, the bookmakers currently have the Cubs at $1.61 and the Rays at $2.40.

The Cubs are listed as 1.5-run favourites against the Rays, with odds of $2.29 available at TAB.

For the underdog Rays (+1.5) to cover the line, TAB offers odds of $1.65.

The over/under for total runs scored is set at 7.5 with TAB, which has odds of $1.91 for the over and $1.91 for the under.

According to Stats Insider's model, the Rays (+1.5) are predicted to cover the line 58% of the time, while the 7.5-run over/under is expected to go over 51% of the time.

Cubs vs Rays: Best Bets

  • Head to Head: Cubs at $1.61 with TAB
  • Line: Cubs -1.5 at $2.29 with TAB
  • Total Runs: Over 7.5 at $1.91 with TAB

These Cubs vs Rays predictions are based on world-class simulations and gambling intelligence to provide you with the best possible advice every day of the year.

Although the Rays are more likely to cover the line, our best bet of Cubs -1.5 is based on the probability of that happening, as suggested by our predictive analytics model, and the best odds available.

Cubs vs Rays: Prediction

Stats Insider provides full coverage of the Cubs vs Tampa Bay game on Monday, including data-driven predictions and live win probabilitiestips.

Remember, our model updates regularly, so refresh this page for the latest betting predictions before the Cubs vs Tampa Bay match-up.

As always, see our Best Bets for betting tips on every MLB game, as well as predictions for a wide range of other sports.

Cubs vs Rays: Essential Details

The match-up between the Cubs and Rays at Wrigley Field is scheduled to commence at 4:20am AEST on Monday.

All dates and times in this article are in Australian Eastern Standard Time (AEST), unless otherwise noted.

Conclusion

Our Cubs vs Tampa Bay predictions have been made based on 10,000 data-driven simulations of the game, all curated by our team of skilled data scientists and analysts. We use the latest in predictive analytics technology and machine learning to ensure our MLB tips are trustworthy and reliable, so that you can make informed decisions with confidence.

If you decide to use our predictions for betting purposes, it's crucial to gamble responsibly and keep track of your money. For free and confidential support, call 1800 858 858 or visit gamblinghelponline.org.au.

More on MLB

Stats Insider is your home for betting on the MLB in Australia, with the latest MLB betting news, tips for every MLB game, and futures odds for the MLB.

Stats Insider

Stats Insider, Australia's leading predictive analytics website, offers Australian sports fans innovative tools and content to enhance their enjoyment of major sporting events both domestically and internationally. Our goal is to transform the sports fan experience by providing readily accessible, data-driven content for sports enthusiasts like us.

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