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Cubs vs Pirates Prediction and MLB Tips - 16 June 2025

The Chicago Cubs will sqaure off with the Pittsburgh Pirates in MLB action at Wrigley Field on Monday, commencing at 4:20am AEST.

Colin Rea (4-2, 3.92 ERA) will start for the Cubs, while the Pirates will counter with Mitch Keller (1-9, 4.15 ERA).

This article features Stats Insider's prediction and tips for the Cubs vs Pirates game, plus the latest betting odds in Australia.

Who Will Win?

Using trusted machine learning and data, Stats Insider has simulated the outcome of Monday's Cubs vs Pittsburgh MLB game 10,000 times.

Our independent predictive analytics model gives the Cubs a 57% chance of defeating the Pirates at Wrigley Field.

Cubs vs Pirates: Odds

The latest betting odds in Australia for Monday's MLB game at Wrigley Field are shown here:

  • Head to Head: Cubs $1.66, Pirates $2.25
  • Line: Cubs -1.5 ($2.50), Pirates +1.5 ($1.55)
  • Total (Over/Under 7 Runs): Over $1.91, Under $1.91

Odds are correct at the time of publication and subject to change.

Looking at the latest head-to-head odds, the bookmakers currently have the Cubs at $1.66 and the Pirates at $2.25.

The Cubs are listed as 1.5-run favourites against the Pirates, with odds of $2.50 available at TAB.

For the underdog Pirates (+1.5) to cover the line, TAB offers odds of $1.55.

The over/under for total runs scored is set at 7 with TAB, which has odds of $1.91 for the over and $1.91 for the under.

According to Stats Insider's model, the Pirates (+1.5) are predicted to cover the line 63% of the time, while the 7-run over/under is expected to go over 52% of the time.

Cubs vs Pirates: Best Bets

  • Head to Head: Pittsburgh at $2.25 with TAB
  • Line: Pirates +1.5 at $1.55 with TAB
  • Total Runs: Over 7 at $1.91 with TAB

Today's Cubs vs Pirates betting tips are based on world-class modelling and betting intelligence to give you the best possible advice around the clock.

While the Cubs have a higher chance of winning the game, betting on the Pirates to win is our recommended option because of the edge identified when comparing our data-led probabilities to the odds currently on offer.

Making use of the edges published here at Stats Insider is one of the keys to being profitable in the long run.

Cubs vs Pirates: Prediction

Stats Insider provides full coverage of the Cubs vs Pittsburgh game on Monday, including data-driven predictions and expert tips.

Remember, our model updates frequently, so refresh this article for the latest betting tips before the Cubs vs Pittsburgh match-up.

As always, see Stats Insider's Best Bets for the best tips on every MLB game, as well as predictions for a wide range of other sports.

Cubs vs Pirates: Essential Details

The match-up between the Cubs and Pirates at Wrigley Field is scheduled to begin at 4:20am AEST on Monday.

All dates and times in this article are in Australian Eastern Standard Time (AEST), unless otherwise noted.

Conclusion

Our Cubs vs Pittsburgh predictions are based on 10,000 data-driven simulations of the game, carefully curated by our team of experienced data scientists and analysts. We use cutting-edge technology and machine learning to ensure our MLB tips are accurate and reliable, giving you the confidence to make informed decisions.

If you choose to use our MLB predictions for betting purposes, it's important to gamble responsibly and keep track of your money. For free and confidential support, call 1800 858 858 or visit gamblinghelponline.org.au.

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Stats Insider is your home for betting on the MLB in Australia, with the latest MLB betting news, predictions for every MLB game, and futures probabilities for the MLB.

Stats Insider

Stats Insider, Australia's leading predictive analytics website, offers Australian sports fans innovative tools and content to enhance their enjoyment of major sporting events both domestically and internationally. Our goal is to transform the sports fan experience by providing readily accessible, data-driven content for sports enthusiasts like us.

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