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Cubs vs Pirates Prediction and MLB Tips - 16 August 2025

The Chicago Cubs will take on the Pittsburgh Pirates in MLB action at Wrigley Field on Saturday, starting at 4:20am AEST.

Colin Rea (9-5, 4.09 ERA) will get the ball for the Cubs, up against Braxton Ashcraft (3-2, 3.19 ERA) for the Pirates.

This article features Stats Insider's prediction and tips for the Cubs vs Pirates game, as well as the latest betting odds in Australia.

Who Will Win?

Utilising advanced machine learning and data, Stats Insider has simulated the result of Saturday's Cubs vs Pittsburgh MLB game 10,000 times.

Our independent predictive analytics model currently gives the Cubs a 64% chance of defeating the Pirates at Wrigley Field.

Cubs vs Pirates: Odds

The latest betting odds in Australia for Saturday's MLB game at Wrigley Field are shown here:

  • Head to Head: Cubs $1.50, Pirates $2.62
  • Line: Cubs -1.5 ($2.02), Pirates +1.5 ($1.81)
  • Total (Over/Under 8.5 Runs): Over $1.91, Under $1.91

Odds are correct at the time of publication and subject to change.

Looking at the latest head-to-head odds, the bookmakers currently have the Cubs at $1.50 and the Pirates at $2.62.

The Cubs are 1.5-run favourites against the Pirates, with odds of $2.02 available at TAB.

For the underdog Pirates (+1.5) to cover the line, TAB offers odds of $1.81.

The over/under for total runs scored is set at 8.5 with TAB, which has odds of $1.91 for the over and $1.91 for the under.

According to Stats Insider's model, the Pirates (+1.5) are predicted to cover the line 55% of the time, while the 8.5-run over/under is expected to is considered an equal 50-50 chance of hitting.

Cubs vs Pirates: Best Bets

  • Head to Head: Cubs at $1.50 with TAB
  • Line: Pirates +1.5 at $1.81 with TAB
  • Total Runs: Under 8.5 at $1.91 with TAB

Our Cubs vs Pirates predictions are based on complex modelling and gambling expertise to help you place more informed bets with your chosen online bookie.

Cubs vs Pirates: Prediction

Stats Insider provides full betting coverage of the Cubs vs Pittsburgh game on Saturday, including data-driven predictions and top betting tips.

Our model updates regularly, so refresh this page for the latest betting predictions before the Cubs vs Pittsburgh match-up.

As always, see Stats Insider's Best Bets for the best tips on every MLB game, plus predictions for a wide range of other sports.

Cubs vs Pirates: Essential Details

The game between the Cubs and Pirates at Wrigley Field is scheduled to begin at 4:20am AEST on Saturday.

All dates and times in this article are in Australian Eastern Standard Time (AEST), unless otherwise noted.

Conclusion

Our Cubs vs Pittsburgh predictions are based on 10,000 data-driven simulations of the game, all curated by our team of expert data scientists and analysts. We use cutting-edge technology and machine learning to ensure our MLB tips are accurate and reliable, giving you the knowledge you need to make informed decisions with confidence.

If you decide to use our predictions for betting purposes, it's important that you gamble responsibly and keep track of your money. For free and confidential support, call 1800 858 858 or visit gamblinghelponline.org.au.

More on MLB

Stats Insider is your home for betting on the MLB in Australia, with the latest MLB betting news, tips for every MLB game, and futures odds for the MLB.

Stats Insider

Stats Insider, Australia's leading predictive analytics website, offers Australian sports fans innovative tools and content to enhance their enjoyment of major sporting events both domestically and internationally. Our goal is to transform the sports fan experience by providing readily accessible, data-driven content for sports enthusiasts like us.

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