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Cubs vs Padres Prediction and MLB Tips - 2 October 2025

The Chicago Cubs will face the San Diego Padres in Game of the League Series at Wrigley Field on Thursday, starting at 5:08am AEST.

The Cubs will send Andrew Kittredge (0-0, 0.00 ERA) to the mound, pitting him against Dylan Cease (0-0, 0.00 ERA) for the Padres.

This article features Stats Insider's top betting tips for the Cubs vs Padres game, plus the latest betting odds in Australia.

Who Will Win?

Using advanced computer power and data, Stats Insider has simulated the outcome of Thursday's Cubs vs San Diego MLB match-up 10,000 times.

Our independent predictive analytics model is currently unable to split the two teams, giving both the Cubs and the Padres an equal 50% chance of winning the game.

Cubs vs Padres: Odds

The current betting odds in Australia for Thursday's MLB game at Wrigley Field are shown here:

  • Head to Head: Cubs $1.91, Padres $1.91
  • Line: Cubs -1.5 ($2.90), Padres +1.5 ($1.43)
  • Total (Over/Under 6.5 Runs): Over $1.91, Under $1.91

Odds are correct at the time of publication and subject to change.

Looking at the latest head-to-head odds, the bookmakers currently have the Cubs at $1.91 and the Padres at $1.91.

The Cubs are listed as 1.5-run favourites against the Padres, with odds of $2.90 available at TAB.

For the underdog Padres (+1.5) to cover the line, TAB offers odds of $1.43.

The over/under for total runs scored is set at 6.5 with TAB, which has odds of $1.91 for the over and $1.91 for the under.

According to Stats Insider's analytics model, the Padres (+1.5) are predicted to cover the line 68% of the time, while the 6.5-run over/under is expected to go over 63% of the time.

Cubs vs Padres: Best Bets

  • Head to Head: San Diego at $1.91 with TAB
  • Line: Padres +1.5 at $1.43 with TAB
  • Total Runs: Over 6.5 at $1.91 with TAB

Today's Cubs vs Padres best bets are based on market-leading simulations and gambling expertise to bring you the best possible advice around the clock.

Cubs vs Padres: Prediction

Stats Insider provides full betting coverage of the Cubs vs San Diego game on Thursday, including data-driven predictions and free tips.

Remember, our model updates regularly, so keep checking this page for the latest betting tips before the Cubs vs San Diego game.

As always, see our Best Bets for betting tips for every MLB game, plus predictions for a wide range of other sports.

Cubs vs Padres: Essential Details

The game between the Cubs and Padres at Wrigley Field is scheduled to begin at 5:08am AEST on Thursday.

All dates and times in this article are in Australian Eastern Standard Time (AEST), unless otherwise stated.

Conclusion

Our Cubs vs San Diego predictions are based on 10,000 data-driven simulations of the game, carefully curated by our team of skilled data scientists and analysts. We use the latest in predictive analytics technology and machine learning to ensure our MLB tips are accurate and reliable, giving you the confidence to make informed decisions.

If you choose to use our predictions for betting purposes, it's crucial that you gamble responsibly and know when to stop. For free and confidential support, call 1800 858 858 or visit gamblinghelponline.org.au.

More on MLB

Stats Insider is your home for betting on the MLB in Australia, with the latest MLB betting news, predictions for every MLB game, and futures odds for the MLB.

Stats Insider

Stats Insider, Australia's leading predictive analytics website, offers Australian sports fans innovative tools and content to enhance their enjoyment of major sporting events both domestically and internationally. Our goal is to transform the sports fan experience by providing readily accessible, data-driven content for sports enthusiasts like us.

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