Cubs vs Nationals Prediction and MLB Tips - 6 September 2025
Last updated: Sep 5, 2025, 6:23PM | Published: Sep 4, 2025, 7:32PM
The Chicago Cubs will take on the Washington Nationals in MLB action at Wrigley Field on Saturday, commencing at 4:20am AEST.
The Cubs will have Javier Assad (1-1, 4.05 ERA) start, pitting him against Jake Irvin (8-10, 5.42 ERA) for the Nationals.
This article features Stats Insider's prediction and tips for the Cubs vs Nationals game, plus the latest betting odds in Australia.
Who Will Win?
Based on trusted computer power and data, Stats Insider has simulated the outcome of Saturday's Cubs vs Washington MLB game 10,000 times.
Our independent predictive analytics model currently gives the Cubs a 63% chance of winning against the Nationals at Wrigley Field.
Cubs vs Nationals: Odds
The current betting odds in Australia for Saturday's MLB game at Wrigley Field are shown here:
- Head to Head: Cubs $1.46, Nationals $2.77
- Line: Cubs -1.5 ($1.93), Nationals +1.5 ($1.88)
- Total (Over/Under 10.5 Runs): Over $1.91, Under $1.91
Odds are correct at the time of publication and subject to change.
Looking at the latest head-to-head odds, the bookmakers currently have the Cubs at $1.46 and the Nationals at $2.77.
The Cubs are 1.5-run favourites against the Nationals, with odds of $1.93 available at TAB.
For the underdog Nationals (+1.5) to cover the line, TAB offers odds of $1.88.
The over/under for total runs scored is set at 10.5 with TAB, which has odds of $1.91 for the over and $1.91 for the under.
According to Stats Insider's model, the Nationals (+1.5) are predicted to cover the line 54% of the time, while the 10.5-run over/under is expected to stay under 56% of the time.
Cubs vs Nationals: Best Bets
- Head to Head: Washington at $2.77 with TAB
- Line: Nationals +1.5 at $1.88 with TAB
- Total Runs: Under 10.5 at $1.91 with TAB
Today's Cubs vs Nationals predictions are based on complex simulations and gambling expertise to bring you the best possible advice 24/7/365.
While the Cubs have a higher chance of winning the game, betting on the Nationals to win is our preferred option due to the 2.0% edge found when comparing our data-led probabilities to the odds currently on offer.
Taking advantage of the edges seen here at Stats Insider is crucial to being a profitable sports bettor in the long run.
Cubs vs Nationals: Prediction
Stats Insider provides full coverage of the Cubs vs Washington game on Saturday, including data-driven predictions and top betting tips.
Our model updates regularly, so keep checking this page for the latest betting tips before the Cubs vs Washington match-up.
As always, see Stats Insider's Best Bets to get betting tips on every MLB game, as well as predictions for a wide range of other sports.
Cubs vs Nationals: Essential Details
The game between the Cubs and Nationals at Wrigley Field is scheduled to begin at 4:20am AEST on Saturday.
- Teams: Chicago Cubs vs Washington Nationals
- Date: Saturday 6 September 2025
- Time: 4:20am AEST
- Venue: Wrigley Field
All dates and times in this article are in Australian Eastern Standard Time (AEST), unless otherwise noted.
Conclusion
Our Cubs vs Washington predictions are based on 10,000 data-driven simulations of the game, carefully curated by our team of skilled data scientists and analysts. We use cutting-edge technology and machine learning to ensure our MLB tips are accurate and reliable, giving you the confidence to make informed decisions.
If you choose to use our predictions for betting purposes, it's crucial that you gamble responsibly and keep track of your money. For free and confidential support, call 1800 858 858 or visit gamblinghelponline.org.au.
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