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Cubs vs Mariners Prediction and MLB Tips - 22 June 2025

The Chicago Cubs will take on the Seattle Mariners in MLB action at Wrigley Field on Sunday, starting at 4:20am AEST.

Cade Horton (3-1, 3.47 ERA) will start for the Cubs, up against Emerson Hancock (3-2, 4.48 ERA) for the Mariners.

This article features Stats Insider's prediction and tips for the Cubs vs Mariners game, as well as the latest betting odds in Australia.

Who Will Win?

Based on trusted computer power and data, Stats Insider has simulated the outcome of Sunday's Cubs vs Seattle MLB match-up 10,000 times.

Our independent predictive analytics model gives the Cubs a 61% chance of beating the Mariners at Wrigley Field.

Cubs vs Mariners: Odds

The latest betting odds in Australia for Sunday's MLB game at Wrigley Field are shown below:

  • Head to Head: Cubs $1.60, Mariners $2.43
  • Line: Cubs -1.5 ($2.08), Mariners +1.5 ($1.78)
  • Total (Over/Under 12.286 Runs): Over $1.91, Under $1.91

Odds are correct at the time of publication and subject to change.

Looking at the latest head-to-head odds, the bookmakers currently have the Cubs at $1.60 and the Mariners at $2.43.

The Cubs are listed as 1.5-run favourites against the Mariners, with odds of $2.08 available at TAB.

For the underdog Mariners (+1.5) to cover the line, TAB offers odds of $1.78.

The over/under for total runs scored is set at 12.286 with TAB, which has odds of $1.91 for the over and $1.91 for the under.

According to Stats Insider's analytics model, the Mariners (+1.5) are predicted to cover the line 55% of the time, while the 12.286-run over/under is expected to stay under 59% of the time.

Cubs vs Mariners: Best Bets

  • Head to Head: Cubs at $1.60 with TAB
  • Line: Mariners +1.5 at $1.78 with TAB
  • Total Runs: Under 12.286 at $1.91 with TAB

Today's Cubs vs Mariners best bets are based on world-class simulations and wagering expertise to give you the best possible advice 24/7.

Cubs vs Mariners: Prediction

Stats Insider provides full betting coverage of the Cubs vs Seattle game on Sunday, including data-driven predictions and live scorestips.

Our model updates regularly, so bookmark this page for the latest betting analysis before the Cubs vs Seattle match-up.

As always, see our Best Bets for the best tips for every MLB game, as well as predictions for a wide range of other sports.

Cubs vs Mariners: Essential Details

The match-up between the Cubs and Mariners at Wrigley Field is scheduled to begin at 4:20am AEST on Sunday.

All dates and times in this article are in Australian Eastern Standard Time (AEST), unless otherwise stated.

Conclusion

Our Cubs vs Seattle predictions have been made after running 10,000 data-driven simulations of the game, all curated by our team of skilled data scientists and analysts. We use the latest in predictive analytics technology and machine learning to ensure our MLB tips are trustworthy and reliable, so that you can make informed decisions with confidence.

If you choose to use our predictions for betting purposes, it's vital that you gamble responsibly and manage your finances effectively. For free and confidential support, call 1800 858 858 or visit gamblinghelponline.org.au.

More on MLB

Stats Insider is your home for betting on the MLB in Australia, with the latest MLB betting news, tips for every MLB game, and futures odds for the MLB.

Stats Insider

Stats Insider, Australia's leading predictive analytics website, offers Australian sports fans innovative tools and content to enhance their enjoyment of major sporting events both domestically and internationally. Our goal is to transform the sports fan experience by providing readily accessible, data-driven content for sports enthusiasts like us.

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