Cubs vs Guardians Prediction and MLB Tips - 4 July 2025
Last updated: Jul 4, 2025, 12:05AM | Published: Jul 2, 2025, 7:30PM
The Chicago Cubs will face the Cleveland Guardians in MLB action at Wrigley Field on Friday, beginning at 10:05am AEST.
Cade Horton (3-2, 4.80 ERA) will be on the bump for the Cubs, pitting him against Joey Cantillo (1-0, 3.81 ERA) for the Guardians.
This article features Stats Insider's top betting tips for the Cubs vs Guardians game, along with the latest betting odds in Australia.
Who Will Win?
Utilising trusted computer power and data, Stats Insider has simulated the result of Friday's Cubs vs Cleveland MLB match-up 10,000 times.
Our independent predictive analytics model gives the Cubs a 55% chance of beating the Guardians at Wrigley Field.
Cubs vs Guardians: Odds
The current betting odds in Australia for Friday's MLB game at Wrigley Field are shown here:
- Head to Head: Cubs $1.74, Guardians $2.15
- Line: Cubs -1.5 ($2.54), Guardians +1.5 ($1.54)
- Total (Over/Under 8.5 Runs): Over $1.91, Under $1.91
Odds are correct at the time of publication and subject to change.
Looking at the latest head-to-head odds, the bookmakers currently have the Cubs at $1.74 and the Guardians at $2.15.
The Cubs are listed as 1.5-run favourites against the Guardians, with odds of $2.54 available at TAB.
For the underdog Guardians (+1.5) to cover the line, TAB offers odds of $1.54.
The over/under for total runs scored is set at 8.5 with TAB, which has odds of $1.91 for the over and $1.91 for the under.
According to Stats Insider's analytics model, the Guardians (+1.5) are predicted to cover the line 63% of the time, while the 8.5-run over/under is expected to stay under 56% of the time.
Cubs vs Guardians: Betting Tips
- Head to Head: Cleveland at $2.15 with TAB
- Line: Guardians +1.5 at $1.54 with TAB
- Total Runs: Under 8.5 at $1.91 with TAB
Today's Cubs vs Guardians best bets are based on world-class modelling and wagering experience to give you the best possible advice 24/7/365.
While the Cubs have a higher chance of winning the game, betting on the Guardians to win is our preferred option due to the edge identified when comparing our data-driven probabilities to the odds currently available.
Making use of the edges seen here at Stats Insider is pivotal to achieving long-term success as a punter.
Cubs vs Guardians: Prediction
Stats Insider provides full betting coverage of the Cubs vs Cleveland game on Friday, including data-driven predictions and top betting tips.
Our model updates regularly, so refresh this article for the latest betting predictions before the Cubs vs Cleveland game.
As always, see Stats Insider's Best Bets to get the best tips for every MLB game, as well as predictions for a wide range of other sports.
Cubs vs Guardians: Essential Details
The match-up between the Cubs and Guardians at Wrigley Field is scheduled to start at 10:05am AEST on Friday.
- Teams: Chicago Cubs vs Cleveland Guardians
- Date: Friday 4 July 2025
- Time: 10:05am AEST
- Venue: Wrigley Field
All dates and times in this article are in Australian Eastern Standard Time (AEST), unless otherwise noted.
Conclusion
Our Cubs vs Cleveland predictions are the result of 10,000 data-driven simulations of the game, carefully curated by our team of skilled data scientists and analysts. We use the latest in predictive analytics technology and machine learning to ensure our MLB tips are trustworthy and reliable, giving you the knowledge you need to make informed decisions with confidence.
If you decide to use our MLB predictions for betting purposes, it's crucial to gamble responsibly and keep track of your money. For free and confidential support, call 1800 858 858 or visit gamblinghelponline.org.au.
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