Cubs vs Cardinals Prediction and MLB Tips - 5 July 2025
Last updated: Jul 4, 2025, 6:21PM | Published: Jul 3, 2025, 8:30PM
The Chicago Cubs will sqaure off with the St. Louis Cardinals in MLB action at Wrigley Field on Saturday, commencing at 4:20am AEST.
The Cubs will have Colin Rea (5-3, 4.37 ERA) start, pitting him against Miles Mikolas (4-5, 4.76 ERA) for the Cardinals.
This article features Stats Insider's prediction and tips for the Cubs vs Cardinals game, along with the latest betting odds in Australia.
Who Will Win?
Using advanced computer power and data, Stats Insider has simulated the outcome of Saturday's Cubs vs St. Louis MLB match-up 10,000 times.
Our leading predictive analytics model gives the Cubs a 56% chance of defeating the Cardinals at Wrigley Field.
Cubs vs Cardinals: Odds
The latest betting odds in Australia for Saturday's MLB game at Wrigley Field are listed below:
- Head to Head: Cubs $1.67, Cardinals $2.25
- Line: Cubs -1.5 ($2.29), Cardinals +1.5 ($1.65)
- Total (Over/Under 9.5 Runs): Over $1.91, Under $1.91
Odds are correct at the time of publication and subject to change.
Looking at the latest head-to-head odds, the bookmakers currently have the Cubs at $1.67 and the Cardinals at $2.25.
The Cubs are listed as 1.5-run favourites against the Cardinals, with odds of $2.29 available at TAB.
For the underdog Cardinals (+1.5) to cover the line, TAB offers odds of $1.65.
The over/under for total runs scored is set at 9.5 with TAB, which has odds of $1.91 for the over and $1.91 for the under.
According to Stats Insider's model, the Cardinals (+1.5) are predicted to cover the line 61% of the time, while the 9.5-run over/under is expected to stay under 55% of the time.
Cubs vs Cardinals: Best Bets
- Head to Head: St. Louis at $2.25 with TAB
- Line: Cardinals +1.5 at $1.65 with TAB
- Total Runs: Under 9.5 at $1.91 with TAB
These Cubs vs Cardinals predictions are based on complex modelling and betting experience to bring you the best possible advice around the clock.
While the Cubs have a higher chance of winning the game, betting on the Cardinals to win is our recommended option because of the 1.5% edge identified when comparing our data-led probabilities to the odds currently on offer.
Taking advantage of the edges published here at Stats Insider is crucial to being profitable in the long run.
Cubs vs Cardinals: Prediction
Stats Insider provides full betting coverage of the Cubs vs St. Louis game on Saturday, including data-driven predictions and live win probabilitiestips.
Remember, our model updates frequently, so keep checking this page for the latest betting analysis before the Cubs vs St. Louis match-up.
As always, see our Best Bets to get the best tips for every MLB game, plus predictions for a wide range of other sports.
Cubs vs Cardinals: Essential Details
The match-up between the Cubs and Cardinals at Wrigley Field is scheduled to commence at 4:20am AEST on Saturday.
- Teams: Chicago Cubs vs St. Louis Cardinals
- Date: Saturday 5 July 2025
- Time: 4:20am AEST
- Venue: Wrigley Field
All dates and times in this article are in Australian Eastern Standard Time (AEST), unless otherwise noted.
Conclusion
Our Cubs vs St. Louis predictions are the result of 10,000 data-driven simulations of the game, all curated by our team of expert data scientists and analysts. We use the latest in predictive analytics technology and machine learning to ensure our MLB tips are accurate and reliable, so that you can make informed decisions with confidence.
If you choose to use our MLB predictions for betting purposes, it's vital to gamble responsibly and know when to stop. For free and confidential support, call 1800 858 858 or visit gamblinghelponline.org.au.
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