Cubs vs Brewers Prediction and MLB Tips - 22 August 2025
Last updated: Aug 21, 2025, 6:15PM | Published: Aug 20, 2025, 6:32PM
The Chicago Cubs will face the Milwaukee Brewers in MLB action at Wrigley Field on Friday, commencing at 4:20am AEST.
The Cubs will have Shota Imanaga (8-5, 3.06 ERA) start, up against Quinn Priester (11-2, 3.48 ERA) for the Brewers.
This article features Stats Insider's prediction and tips for the Cubs vs Brewers game, as well as the latest betting odds in Australia.
Who Will Win?
Using trusted machine learning and data, Stats Insider has simulated the result of Friday's Cubs vs Milwaukee MLB game 10,000 times.
Our independent predictive analytics model currently gives the Cubs a 57% chance of winning against the Brewers at Wrigley Field.
Cubs vs Brewers: Odds
The current betting odds in Australia for Friday's MLB game at Wrigley Field are listed below:
- Head to Head: Cubs $1.71, Brewers $2.16
- Line: Cubs -1.5 ($2.65), Brewers +1.5 ($1.49)
- Total (Over/Under 6.5 Runs): Over $1.91, Under $1.91
Odds are correct at the time of publication and subject to change.
Looking at the latest head-to-head odds, the bookmakers currently have the Cubs at $1.71 and the Brewers at $2.16.
The Cubs are 1.5-run favourites against the Brewers, with odds of $2.65 available at TAB.
For the underdog Brewers (+1.5) to cover the line, TAB offers odds of $1.49.
The over/under for total runs scored is set at 6.5 with TAB, which has odds of $1.91 for the over and $1.91 for the under.
According to Stats Insider's model, the Brewers (+1.5) are predicted to cover the line 63% of the time, while the 6.5-run over/under is expected to go over 54% of the time.
Cubs vs Brewers: Best Bets
- Head to Head: Cubs at $1.71 with TAB
- Line: Cubs -1.5 at $2.65 with TAB
- Total Runs: Over 6.5 at $1.91 with TAB
Our Cubs vs Brewers best bets are based on detailed simulations and betting expertise to bring you the best possible advice around the clock.
Even though the Brewers are more likely to cover the line, our best bet of Cubs -1.5 is based on the chance of that happening, as suggested by our predictive analytics model, and the best odds available.
Cubs vs Brewers: Prediction
Stats Insider provides full betting coverage of the Cubs vs Milwaukee game on Friday, including data-driven predictions and expert tips.
Remember, our model updates regularly, so keep checking this page for the latest betting predictions before the Cubs vs Milwaukee match-up.
As always, see Stats Insider's Best Bets to get the best tips on every MLB game, plus predictions for a wide range of other sports.
Cubs vs Brewers: Essential Details
The game between the Cubs and Brewers at Wrigley Field is scheduled to commence at 4:20am AEST on Friday.
- Teams: Chicago Cubs vs Milwaukee Brewers
- Date: Friday 22 August 2025
- Time: 4:20am AEST
- Venue: Wrigley Field
All dates and times in this article are in Australian Eastern Standard Time (AEST), unless otherwise stated.
Conclusion
Our Cubs vs Milwaukee predictions have been made after running 10,000 data-driven simulations of the game, all curated by our team of expert data scientists and analysts. We use cutting-edge technology and machine learning to ensure our MLB tips are accurate and reliable, so that you can make informed decisions with confidence.
If you choose to use our predictions for betting purposes, it's vital to gamble responsibly and keep track of your money. For free and confidential support, call 1800 858 858 or visit gamblinghelponline.org.au.
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