Cowboys vs Panthers Prediction and Tips - NRL Round 10, 2025

The Cowboys will sqaure off with the Panthers in NRL Round 10 action at Queensland Country Bank Stadium on Saturday, starting at 7:35pm AEST.

This article features Stats Insider's prediction and tips for the Cowboys vs Panthers game, along with the latest betting odds and try scorer tips.

Who Will Win?

Utilising advanced machine learning and data, Stats Insider has simulated the result of Saturday's North Queensland vs Penrith NRL match 10,000 times.

Our proven predictive analytics model currently gives the Panthers a 63% chance of beating the Cowboys at Queensland Country Bank Stadium.

Cowboys vs Panthers: Odds

The current Bet365 betting odds for Saturday's NRL clash at Queensland Country Bank Stadium are shown here:

  • Head to Head: Cowboys $2.45, Panthers $1.56
  • Line: Cowboys +4.5 ($1.91), Panthers -4.5 ($1.91)
  • Total (Over/Under 48.5 Points): Over $1.91, Under $1.91

Odds are correct at the time of publication and subject to change.

Looking at the latest head-to-head odds, Bet365 currently has the Cowboys at $2.45 and the Panthers at $1.56.

The Cowboys are 4.5-point underdogs against the Panthers, with odds of $1.91 available at Bet365.

For the favourite Panthers (-4.5) to cover the line, Bet365 offers odds of $1.91.

The over/under for total points scored is set at 48.5 with Bet365, which has odds of $1.91 for the over and $1.91 for the under.

According to Stats Insider's model, the Panthers (-4.5) are predicted to cover the line 51% of the time, while the 48.5-point over/under is expected to stay under 55% of the time.

Cowboys vs Panthers: Best Bets

  • Head to Head: Panthers at $1.56 with Bet365
  • Line: Panthers -4.5 at $1.91 with Bet365
  • Total Points: Under 48.5 at $1.91 with Bet365

Our Cowboys vs Panthers predictions are based on detailed simulations and wagering intelligence to help you place more informed bets with your chosen online bookie.

Cowboys vs Panthers: Prediction

Stats Insider's predicted final score for Cowboys vs Panthers at Queensland Country Bank Stadium on Saturday is the Panthers winning 25-20.

This prediction is based on each team's average score following 10,000 game simulations.

Stats Insider provides full betting coverage of the Cowboys vs Panthers match on Saturday, including data-driven predictions and live win probabilitiestips.

18+. Odds correct at time of publishing and subject to change.

Cowboys vs Panthers: Try Scorers

Looking for Cowboys vs Panthers try scorers? The latest data is in.

According to Stats Insider, the Panthers' Brian To'o is the most likely player to score the first try in North Queensland vs Penrith.

To'o has a 9.1% chance of scoring the first try at Queensland Country Bank Stadium, while the Panthers star has a 52.8% chance of scoring a try at any time during the game.

Scroll down for the full list of first try scorer and anytime try scorer probabilities.

First Try Scorer Tips

North Queensland Cowboys

  • Murray Taulagi: 7.5% probability
  • Robert Derby: 6.2% probability
  • Jeremiah Nanai: 5.8% probability
  • Jaxon Purdue: 5.4% probability
  • Scott Drinkwater: 4.1% probability

Penrith Panthers

  • Brian To'o: 9.1% probability
  • Paul Alamoti: 6.9% probability
  • Izack Tago: 6.0% probability
  • Dylan Edwards: 5.2% probability
  • Luke Garner: 4.4% probability

Anytime Try Scorer Tips

North Queensland Cowboys

  • Murray Taulagi: 45.2% probability
  • Robert Derby: 40.3% probability
  • Jeremiah Nanai: 39.4% probability
  • Jaxon Purdue: 36.4% probability
  • Scott Drinkwater: 28.7% probability

Penrith Panthers

  • Brian To'o: 52.8% probability
  • Paul Alamoti: 43.0% probability
  • Izack Tago: 37.9% probability
  • Dylan Edwards: 35.8% probability
  • Luke Garner: 31.8% probability

Our model updates frequently, so bookmark this article for the latest betting analysis before the Cowboys vs Panthers match.

As always, see Stats Insider's Best Bets for betting tips on every NRL match, as well as predictions for a wide range of other sports.

Cowboys vs Panthers: Essential Details

The NRL Round 10 clash between the Cowboys and Panthers at Queensland Country Bank Stadium is scheduled to start at 7:35pm AEST on Saturday.

All dates and times in this article are in Australian Eastern Standard Time (AEST), unless otherwise stated.

Conclusion

Our Cowboys vs Panthers predictions have been made after running 10,000 data-driven simulations of the match, carefully curated by our team of expert data scientists and analysts. We use cutting-edge technology and machine learning to ensure our rugby league tips are trustworthy and reliable, giving you the confidence to make informed decisions.

If you decide to use our NRL predictions for betting purposes, it's vital to gamble responsibly and keep track of your money. For free and confidential support, call 1800 858 858 or visit gamblinghelponline.org.au.

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