Cowboys vs Panthers Prediction and Tips - NRL Round 10, 2025

The Cowboys will take on the Panthers in NRL Round 10 action at Queensland Country Bank Stadium on Saturday, beginning at 7:35pm AEST.

This article features Stats Insider's best betting tips for the Cowboys vs Panthers game, as well as the latest betting odds and try scorer tips.

Who Will Win?

Using trusted machine learning and data, Stats Insider has simulated the result of Saturday's North Queensland vs Penrith NRL match 10,000 times.

Our independent predictive analytics model currently gives the Panthers a 63% chance of winning against the Cowboys at Queensland Country Bank Stadium.

Cowboys vs Panthers: Odds

The latest Bet365 betting odds for Saturday's NRL clash at Queensland Country Bank Stadium are listed here:

  • Head to Head: Cowboys $2.45, Panthers $1.56
  • Line: Cowboys +4.5 ($1.91), Panthers -4.5 ($1.91)
  • Total (Over/Under 48.5 Points): Over $1.91, Under $1.91

Odds are correct at the time of publication and subject to change.

Looking at the latest head-to-head odds, Bet365 currently has the Cowboys at $2.45 and the Panthers at $1.56.

The Cowboys are listed as 4.5-point underdogs against the Panthers, with odds of $1.91 available at Bet365.

For the favourite Panthers (-4.5) to cover the line, Bet365 offers odds of $1.91.

The over/under for total points scored is set at 48.5 with Bet365, which has odds of $1.91 for the over and $1.91 for the under.

According to Stats Insider's model, the Panthers (-4.5) are predicted to cover the line 51% of the time, while the 48.5-point over/under is expected to stay under 55% of the time.

Cowboys vs Panthers: Best Bets

  • Head to Head: Panthers at $1.56 with Bet365
  • Line: Panthers -4.5 at $1.91 with Bet365
  • Total Points: Under 48.5 at $1.91 with Bet365

Today's Cowboys vs Panthers predictions are based on world-class modelling and betting expertise to bring you the best possible advice 24/7/365.

Cowboys vs Panthers: Prediction

Stats Insider's predicted final score for Cowboys vs Panthers at Queensland Country Bank Stadium this Saturday is the Panthers winning 25-20.

This prediction is based on each team's average score from 10,000 game simulations.

Stats Insider provides full coverage of the Cowboys vs Panthers match on Saturday, including data-driven predictions and top betting tips.

18+. Odds correct at time of publishing and subject to change.

Cowboys vs Panthers: Try Scorers

Are you looking for Cowboys vs Panthers try scorers? The latest data is in.

According to Stats Insider, the Panthers' Brian To'o is the most likely player to score the first try in North Queensland vs Penrith.

To'o has a 9.1% chance of scoring the first try at Queensland Country Bank Stadium, while the Panthers star has a 52.8% chance of scoring a try at any time during the game.

Scroll down for our full list of first try scorer and anytime try scorer probabilities.

First Try Scorer Tips

North Queensland Cowboys

  • Murray Taulagi: 7.5% probability
  • Robert Derby: 6.2% probability
  • Jeremiah Nanai: 5.8% probability
  • Jaxon Purdue: 5.4% probability
  • Scott Drinkwater: 4.1% probability

Penrith Panthers

  • Brian To'o: 9.1% probability
  • Paul Alamoti: 6.9% probability
  • Izack Tago: 6.0% probability
  • Dylan Edwards: 5.2% probability
  • Luke Garner: 4.4% probability

Anytime Try Scorer Tips

North Queensland Cowboys

  • Murray Taulagi: 45.2% probability
  • Robert Derby: 40.3% probability
  • Jeremiah Nanai: 39.4% probability
  • Jaxon Purdue: 36.4% probability
  • Scott Drinkwater: 28.7% probability

Penrith Panthers

  • Brian To'o: 52.8% probability
  • Paul Alamoti: 43.0% probability
  • Izack Tago: 37.9% probability
  • Dylan Edwards: 35.8% probability
  • Luke Garner: 31.8% probability

Remember, our model updates regularly, so bookmark this page for the latest betting tips before the Cowboys vs Panthers game.

As always, see our Best Bets to get betting tips on every NRL match, as well as predictions for a wide range of other sports.

Cowboys vs Panthers: Essential Details

The NRL Round 10 clash between the Cowboys and Panthers at Queensland Country Bank Stadium is scheduled to begin at 7:35pm AEST on Saturday.

All dates and times mentioned in this article are in Australian Eastern Standard Time (AEST), unless otherwise noted.

Conclusion

Our Cowboys vs Panthers predictions have been made based on 10,000 data-driven simulations of the game, carefully curated by our team of skilled data scientists and analysts. We use the latest in predictive analytics technology and machine learning to ensure our rugby league tips are accurate and reliable, so that you can make informed decisions with confidence.

If you decide to use our NRL predictions for betting purposes, it's crucial that you gamble responsibly and manage your finances effectively. For free and confidential support, call 1800 858 858 or visit gamblinghelponline.org.au.

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