Cowboys vs Panthers Prediction and Tips - NRL Round 10, 2025
Last updated: May 10, 2025, 9:35AM | Published: May 7, 2025, 5:00AM
The Cowboys will face the Panthers in NRL Round 10 action at Queensland Country Bank Stadium on Saturday, with kick-off at 7:35pm AEST.
This article features Stats Insider's prediction and tips for the Cowboys vs Panthers game, plus the latest betting odds and try scorer tips.
Who Will Win?
Based on trusted computer power and data, Stats Insider has simulated the outcome of Saturday's North Queensland vs Penrith NRL match 10,000 times.
Our proven predictive analytics model currently gives the Panthers a 61% chance of defeating the Cowboys in Round 10 of the 2025 NRL season.
Cowboys vs Panthers: Odds
The latest Bet365 betting odds for Saturday's NRL clash at Queensland Country Bank Stadium are shown below:
- Head to Head: Cowboys $2.50, Panthers $1.56
- Line: Cowboys +4.5 ($1.91), Panthers -4.5 ($1.91)
- Total (Over/Under 48.5 Points): Over $1.91, Under $1.91
Odds are correct at the time of publication and subject to change.
Looking at the latest head-to-head odds, Bet365 currently has the Cowboys at $2.50 and the Panthers at $1.56.
The Cowboys are 4.5-point underdogs against the Panthers, with odds of $1.91 available at Bet365.
For the favourite Panthers (-4.5) to cover the line, Bet365 offers odds of $1.91.
The over/under for total points scored is set at 48.5 with Bet365, which has odds of $1.91 for the over and $1.91 for the under.
According to Stats Insider's model, the bookmakers have got it right and both the Cowboys and the Panthers have a 50% chance of covering the line.
The 48.5-point over/under is expected to stay under 59% of the time.
Cowboys vs Panthers: Best Bets
- Head to Head: Cowboys at $2.50 with Bet365
- Line: Cowboys +4.5 at $1.91 with Bet365
- Total Points: Under 48.5 at $1.91 with Bet365
If you see a 🔥, that means you've found one of Stats Insider's best tips for today across all sports.
These Cowboys vs Panthers betting tips are based on complex modelling and gambling expertise to provide you with the best possible advice every day of the year.
While the Panthers have a higher chance of winning the game, betting on the Cowboys to win is our recommended option because of the edge identified when comparing our data-led probabilities to the odds currently available.
Taking advantage of the edges seen here at Stats Insider is pivotal to being a profitable bettor in the long run.
Cowboys vs Panthers: Prediction
Stats Insider's predicted final score for Cowboys vs Panthers at Queensland Country Bank Stadium on Saturday is the Panthers winning 24-20.
This prediction is based on each team's average score from 10,000 game simulations.
Stats Insider provides full betting coverage of the Cowboys vs Panthers match on Saturday, including data-driven predictions and expert tips.
18+. Odds correct at time of publishing and subject to change.Cowboys vs Panthers: Try Scorers
Are you looking for Cowboys vs Panthers try scorers? The latest data is in.
According to Stats Insider, the Panthers' Brian To'o is the most likely player to score the first try in North Queensland vs Penrith.
To'o has a 9.0% chance of scoring the first try at Queensland Country Bank Stadium, while the Panthers star has a 51.6% chance of scoring a try at any time during the match.
Scroll down for our complete list of first try scorer and anytime try scorer probabilities.
First Try Scorer Tips
North Queensland Cowboys
- Murray Taulagi: 7.5% probability
- Robert Derby: 6.7% probability
- Jeremiah Nanai: 5.9% probability
- Jaxon Purdue: 5.4% probability
- Tom Dearden: 3.6% probability
Penrith Panthers
- Brian To'o: 9.0% probability
- Paul Alamoti: 7.1% probability
- Izack Tago: 6.1% probability
- Dylan Edwards: 5.2% probability
- Luke Garner: 4.3% probability
Anytime Try Scorer Tips
North Queensland Cowboys
- Murray Taulagi: 44.8% probability
- Robert Derby: 39.4% probability
- Jeremiah Nanai: 37.3% probability
- Jaxon Purdue: 36.7% probability
- Scott Drinkwater: 28.5% probability
Penrith Panthers
- Brian To'o: 51.6% probability
- Paul Alamoti: 42.6% probability
- Izack Tago: 37.4% probability
- Dylan Edwards: 34.4% probability
- Luke Garner: 30.1% probability
Our model updates frequently, so refresh this article for the latest betting predictions before the Cowboys vs Panthers match.
As always, see Stats Insider's Best Bets to get betting tips on every NRL match, plus predictions for a wide range of other sports.
Cowboys vs Panthers: Essential Details
The NRL Round 10 clash between the Cowboys and Panthers at Queensland Country Bank Stadium is scheduled to begin at 7:35pm AEST on Saturday.
- Teams: North Queensland Cowboys vs Penrith Panthers
- Date: Saturday 10 May 2025
- Kick-off: 7:35pm AEST
- Location: Queensland Country Bank Stadium
All dates and times in this article are in Australian Eastern Standard Time (AEST), unless otherwise stated.
Conclusion
Our Cowboys vs Panthers predictions have been made thanks to 10,000 data-driven simulations of the match, all curated by our team of skilled data scientists and analysts. We use cutting-edge technology and machine learning to ensure our rugby league tips are accurate and reliable, giving you the confidence to make informed decisions.
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