Cowboys vs Panthers Prediction and Tips - NRL Round 10, 2025
Last updated: May 8, 2025, 6:50AM | Published: May 7, 2025, 5:00AM
The Cowboys will take on the Panthers in NRL Round 10 action at Queensland Country Bank Stadium on Saturday, with kick-off at 7:35pm AEST.
This article features Stats Insider's prediction and tips for the Cowboys vs Panthers game, plus the latest betting odds and try scorer tips.
Who Will Win?
Utilising trusted computer power and data, Stats Insider has simulated the outcome of Saturday's North Queensland vs Penrith NRL match 10,000 times.
Our independent predictive analytics model currently gives the Panthers a 63% chance of defeating the Cowboys in Round 10 of the 2025 NRL season.
Cowboys vs Panthers: Odds
The latest Bet365 betting odds for Saturday's NRL clash at Queensland Country Bank Stadium are listed below:
- Head to Head: Cowboys $2.45, Panthers $1.56
- Line: Cowboys +4.5 ($1.91), Panthers -4.5 ($1.91)
- Total (Over/Under 48.5 Points): Over $1.91, Under $1.91
Odds are correct at the time of publication and subject to change.
Looking at the latest head-to-head odds, Bet365 currently has the Cowboys at $2.45 and the Panthers at $1.56.
The Cowboys are 4.5-point underdogs against the Panthers, with odds of $1.91 available at Bet365.
For the favourite Panthers (-4.5) to cover the line, Bet365 offers odds of $1.91.
The over/under for total points scored is set at 48.5 with Bet365, which has odds of $1.91 for the over and $1.91 for the under.
According to Stats Insider's model, the Panthers (-4.5) are predicted to cover the line 51% of the time, while the 48.5-point over/under is expected to stay under 55% of the time.
Cowboys vs Panthers: Best Bets
- Head to Head: Panthers at $1.56 with Bet365
- Line: Panthers -4.5 at $1.91 with Bet365
- Total Points: Under 48.5 at $1.91 with Bet365
These Cowboys vs Panthers betting tips are based on world-class modelling and betting expertise to help you place smarter bets with your chosen online bookie.
Cowboys vs Panthers: Prediction
Stats Insider's predicted final score for Cowboys vs Panthers at Queensland Country Bank Stadium this Saturday is the Panthers winning 25-20.
This prediction is based on each team's average score following 10,000 game simulations.
Stats Insider provides full betting coverage of the Cowboys vs Panthers match on Saturday, including data-driven predictions and live win probabilitiestips.
18+. Odds correct at time of publishing and subject to change.Cowboys vs Panthers: Try Scorers
Searching for Cowboys vs Panthers try scorers? The latest data is in.
According to Stats Insider, the Panthers' Brian To'o is the most likely player to score the first try in North Queensland vs Penrith.
To'o has a 9.1% chance of scoring the first try at Queensland Country Bank Stadium, while the Panthers star has a 52.8% chance of scoring a try at any time during the game.
Scroll down for our full list of first try scorer and anytime try scorer probabilities.
First Try Scorer Tips
North Queensland Cowboys
- Murray Taulagi: 7.5% probability
- Robert Derby: 6.2% probability
- Jeremiah Nanai: 5.8% probability
- Jaxon Purdue: 5.4% probability
- Scott Drinkwater: 4.1% probability
Penrith Panthers
- Brian To'o: 9.1% probability
- Paul Alamoti: 6.9% probability
- Izack Tago: 6.0% probability
- Dylan Edwards: 5.2% probability
- Luke Garner: 4.4% probability
Anytime Try Scorer Tips
North Queensland Cowboys
- Murray Taulagi: 45.2% probability
- Robert Derby: 40.3% probability
- Jeremiah Nanai: 39.4% probability
- Jaxon Purdue: 36.4% probability
- Scott Drinkwater: 28.7% probability
Penrith Panthers
- Brian To'o: 52.8% probability
- Paul Alamoti: 43.0% probability
- Izack Tago: 37.9% probability
- Dylan Edwards: 35.8% probability
- Luke Garner: 31.8% probability
Our model updates regularly, so keep checking this article for the latest betting analysis before the Cowboys vs Panthers match.
As always, see Stats Insider's Best Bets for the best tips on every NRL match, as well as predictions for a wide range of other sports.
Cowboys vs Panthers: Essential Details
The NRL Round 10 clash between the Cowboys and Panthers at Queensland Country Bank Stadium is scheduled to start at 7:35pm AEST on Saturday.
- Teams: North Queensland Cowboys vs Penrith Panthers
- Date: Saturday 10 May 2025
- Kick-off: 7:35pm AEST
- Location: Queensland Country Bank Stadium
All dates and times in this article are in Australian Eastern Standard Time (AEST), unless otherwise noted.
Conclusion
Our Cowboys vs Panthers predictions are the result of 10,000 data-driven simulations of the match, all curated by our team of experienced data scientists and analysts. We use the latest in predictive analytics technology and machine learning to ensure our rugby league tips are accurate and reliable, giving you the knowledge you need to make informed decisions with confidence.
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