Cowboys vs Chargers Prediction and Preview - NFL Week 16, 2025

The Dallas Cowboys will sqaure off with the Los Angeles Chargers in NFL Week 16 action at AT&T Stadium on Monday, commencing at 5:00am AEDT.

This article features Stats Insider's best betting tips for the Cowboys vs Chargers game, as well as the latest betting odds and touchdown scorer tips.

Who Will Win?

Using trusted machine learning and data, Stats Insider has simulated the outcome of Monday's Dallas vs LA Chargers NFL game 10,000 times.

Our proven predictive analytics model gives the Cowboys a 57% chance of beating the Chargers in Week 16 of the NFL season.

Cowboys vs Chargers: Odds

The current Bet365 betting odds in Australia for Monday's NFL game at AT&T Stadium are listed here:

• Head to Head: Cowboys $1.83, Chargers $2.00
• Line: Cowboys -1 ($1.91), Chargers +1 ($1.91)
• Total (Over/Under 51 Points): Over $1.91, Under $1.91

Odds are correct at the time of publication and subject to change.

Looking at the latest head-to-head odds, Bet365 currently has the Cowboys at $1.83 and the Chargers at $2.00.

The Cowboys are 1-point favourites against the Chargers, with odds of $1.91 available at Bet365.

For the underdog Chargers (+1) to cover the line, Bet365 offers odds of $1.91.

The over/under for total points scored is set at 51 with Bet365, which has odds of $1.91 for the over and $1.91 for the under.

According to Stats Insider's analytics model, the Cowboys (-1) are predicted to cover the line 52% of the time, while the 51-point over/under is expected to stay under 52% of the time.

Cowboys vs Chargers: Best Bets

• Head to Head: Dallas at $1.83 with Bet365
• Line: Cowboys -1 at $1.91 with Bet365
• Total Points: Under 51 at $1.91 with Bet365

Our Cowboys vs Chargers predictions are based on world-class modelling and wagering experience to help you place better bets with your chosen online bookie.

Cowboys vs Chargers: Prediction

Stats Insider's predicted final score for Cowboys vs Chargers at AT&T Stadium in Week 16 is the Cowboys winning 26-24.

This prediction is based on each team's average score from 10,000 game simulations.

Stats Insider provides full coverage of the Dallas vs LA Chargers game in Week 16, including data-driven predictions and live win probabilitiestips.

Get expert analysis from the US with Dimers' in-depth Cowboys vs Chargers prediction.

18+. Odds correct at time of publishing and subject to change.

Cowboys vs Chargers: TD Scorer Tips

Who will score the first touchdown in Cowboys vs Chargers? The data is in.

According to Stats Insider, Dallas' Javonte Williams is the most likely player to score the first touchdown in Cowboys vs Chargers.

Williams has a 12.4% chance of getting in for six first at AT&T Stadium, while the Cowboys RB has a 52.7% chance of scoring an anytime touchdown.

Scroll down for the full list of first touchdown scorer and anytime touchdown scorer probabilities.

First Touchdown Scorer Tips

Cowboys First TD Tips

• Javonte Williams: 12.4% probability
• George Pickens: 8.1% probability
• CeeDee Lamb: 7.9% probability
• Jake Ferguson: 5.5% probability
• Malik Davis: 5.4% probability

Chargers First TD Tips

• Omarion Hampton: 9.0% probability
• Ladd McConkey: 7.4% probability
• Keenan Allen: 6.8% probability
• Quentin Johnston: 6.2% probability
• Kimani Vidal: 6.2% probability

Anytime Touchdown Scorer Tips

Cowboys Anytime TD Tips

• Javonte Williams: 52.7% probability
• George Pickens: 38.5% probability
• CeeDee Lamb: 38.0% probability
• Jake Ferguson: 28.1% probability
• Malik Davis: 27.7% probability

Chargers Anytime TD Tips

• Omarion Hampton: 45.8% probability
• Ladd McConkey: 39.6% probability
• Keenan Allen: 36.9% probability
• Quentin Johnston: 34.4% probability
• Kimani Vidal: 34.2% probability

Cowboys-Chargers Projected Player Stats

Of the starting quarterbacks, the Cowboys' Dak Prescott is projected for 263 passing yards. The Chargers' Justin Herbert is expected to throw for 240 yards.

Cowboys Starting QB

• Dak Prescott: 263 projected passing yards

Chargers Starting QB

• Justin Herbert: 240 projected passing yards

Cowboys Rushing Yards

• Javonte Williams: 73 projected yards
• Malik Davis: 17 projected yards
• Dak Prescott: 11 projected yards

Chargers Rushing Yards

• Omarion Hampton: 56 projected yards
• Kimani Vidal: 41 projected yards
• Justin Herbert: 23 projected yards

Cowboys Receiving Yards

• CeeDee Lamb: 79 projected yards
• George Pickens: 69 projected yards
• Jake Ferguson: 39 projected yards
• Ryan Flournoy: 33 projected yards
• KaVontae Turpin: 17 projected yards

Chargers Receiving Yards

• Ladd McConkey: 54 projected yards
• Keenan Allen: 45 projected yards
• Oronde Gadsden: 43 projected yards
• Quentin Johnston: 36 projected yards
• Tre' Harris: 26 projected yards

Remember, our model updates regularly, so bookmark this article for the latest betting tips before the Dallas vs LA Chargers match-up.

As always, see our Best Bets to get the best tips for every NFL game, plus predictions for a wide range of other sports.

Cowboys vs Chargers: Week 16 Essential Details

The NFL Week 16 game between the Cowboys and Chargers at AT&T Stadium is scheduled to commence at 5:00am AEDT on Monday.

• Teams: Dallas Cowboys vs Los Angeles Chargers
• Date: Monday 22 December 2025
• Time: 5:00am AEDT
• Venue: AT&T Stadium

All dates and times in this article are in Australian Eastern Daylight Time (AEDT), unless otherwise stated.

Conclusion

Our Dallas vs LA Chargers predictions are the result of 10,000 data-driven simulations of the game, carefully curated by our team of expert data scientists and analysts. We use cutting-edge technology and machine learning to ensure our NFL tips are trustworthy and reliable, giving you the confidence to make informed decisions.

If you choose to use our predictions for betting purposes, it's vital that you gamble responsibly and keep track of your money. For free and confidential support, call 1800 858 858 or visit gamblinghelponline.org.au.

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