Commanders vs Lions Prediction and Preview - NFL Week 10, 2025

The Washington Commanders will face the favoured Detroit Lions in NFL Week 10 action at Northwest Stadium on Monday, beginning at 8:25am AEDT.

This article features Stats Insider's top betting tips for the Commanders vs Lions game, as well as the latest betting odds in Australia.

Who Will Win?

Utilising advanced computer power and data, Stats Insider has simulated the outcome of Monday's Washington vs Detroit NFL game 10,000 times.

Our independent predictive analytics model gives the Commanders a 57% chance of defeating the Lions at Northwest Stadium.

Commanders vs Lions: Odds

The latest Bet365 betting odds in Australia for Monday's NFL game at Northwest Stadium are shown below:

• Head to Head: Commanders $4.25, Lions $1.24
• Line: Commanders +7.5 ($1.91), Lions -7.5 ($1.91)
• Total (Over/Under 50.5 Points): Over $1.91, Under $1.91

Odds are correct at the time of publication and subject to change.

Looking at the latest head-to-head odds, Bet365 currently has the Commanders at $4.25 and the Lions at $1.24.

The Commanders are 7.5-point underdogs against the Lions, with odds of $1.91 available at Bet365.

For the favourite Lions (-7.5) to cover the line, Bet365 offers odds of $1.91.

The over/under for total points scored is set at 50.5 with Bet365, which has odds of $1.91 for the over and $1.91 for the under.

According to Stats Insider's analytics model, the Commanders (+7.5) are predicted to cover the line 104% of the time, while the 50.5-point over/under is expected to go over 51% of the time.

Commanders vs Lions: Betting Tips

• Head to Head: Washington at $4.25 with Bet365
• Line: Commanders +7.5 at $1.91 with Bet365
• Total Points: Over 50.5 at $1.91 with Bet365

When you see a 🔥, you know it's one of Stats Insider's best bets for today across all sports.

Today's Commanders vs Lions predictions are based on market-leading simulations and wagering intelligence to help you place smarter bets with your chosen online bookie.

Commanders vs Lions: Prediction

Stats Insider's predicted final score for Commanders vs Lions at Northwest Stadium in Week 10 is the Commanders winning 26-24.

This prediction is based on each team's average score from 10,000 game simulations.

Stats Insider provides full betting coverage of the Washington vs Detroit game in Week 10, including data-driven predictions and live win probabilitiestips.

Our model updates regularly, so keep checking this article for the latest betting tips before the Washington vs Detroit game.

As always, see our Best Bets for the best tips for every NFL game, as well as predictions for a wide range of other sports.

Commanders vs Lions: Week 10 Essential Details

The NFL Week 10 game between the Commanders and Lions at Northwest Stadium is scheduled to begin at 8:25am AEDT on Monday.

• Teams: Washington Commanders vs Detroit Lions
• Date: Monday 10 November 2025
• Time: 8:25am AEDT
• Venue: Northwest Stadium

All dates and times mentioned in this article are in Australian Eastern Daylight Time (AEDT), unless otherwise stated.

Conclusion

Our Washington vs Detroit predictions have been made based on 10,000 data-driven simulations of the game, carefully curated by our team of expert data scientists and analysts. We use the latest in predictive analytics technology and machine learning to ensure our NFL tips are trustworthy and reliable, giving you the knowledge you need to make informed decisions with confidence.

If you decide to use our predictions for betting purposes, it's important to gamble responsibly and manage your finances effectively. For free and confidential support, call 1800 858 858 or visit gamblinghelponline.org.au.

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