Commanders vs Colts Prediction and Preview - NFL Week 4, 2026

The Washington Commanders will sqaure off with the Indianapolis Colts in NFL Week 4 action at Tottenham Hotspur Stadium on Monday, October 5, starting at 12:30am AEDT.

This article features Stats Insider's free betting tips for the Commanders vs Colts game, as well as the latest betting odds in Australia.

Who Will Win?

Based on trusted computer power and data, Stats Insider has simulated the outcome of Colts vs Commanders 10,000 times.

Our leading predictive analytics model gives the Colts a 62% chance of beating the Commanders in Week 4 of the NFL season.

Commanders vs Colts: Odds

The current Bet365 betting odds in Australia for this NFL game at Tottenham Hotspur Stadium are shown here:

• Head to Head: Commanders $2.45, Colts $1.59
• Line: Commanders +3.5 ($1.91), Colts -3.5 ($1.91)
• Total (Over/Under 46.5 Points): Over $1.91, Under $1.91

Odds are correct at the time of publication and subject to change.

Looking at the latest head-to-head odds, Bet365 currently has the Commanders at $2.45 and the Colts at $1.59.

The Commanders are 3.5-point underdogs against the Colts, with odds of $1.91 available at Bet365.

For the favourite Colts (-3.5) to cover the line, Bet365 offers odds of $1.91.

The over/under for total points scored is set at 46.5 with Bet365, which has odds of $1.91 for the over and $1.91 for the under.

According to Stats Insider's model, the bookmakers have got it right and both the Commanders and the Colts have a 50% chance of covering the line.

The 46.5-point over/under is expected to is also considered an equal 50-50 chance of hitting.

Commanders vs Colts: Best Bets

• Head to Head: Indianapolis at $1.59 with Bet365
• Line: Colts -3.5 at $1.91 with Bet365
• Total Points: Under 46.5 at $1.91 with Bet365

Today's Commanders vs Colts best bets are based on world-class simulations and gambling expertise to give you the best possible advice around the clock.

Commanders vs Colts: Prediction

Stats Insider's predicted final score for Commanders vs Colts at Tottenham Hotspur Stadium in Week 4 is the Colts prevailing 25-21.

This prediction is based on each team's average score from 10,000 game simulations.

Stats Insider provides full betting coverage of the Washington vs Indianapolis game in Week 4, including data-driven predictions and free betting tips.

Our model updates regularly, so refresh this article for the latest betting analysis before the Washington vs Indianapolis game.

As always, see our Best Bets for betting tips for every NFL game, plus predictions for a wide range of other sports.

Commanders vs Colts: Week 4 Essential Details

The NFL Week 4 game between the Commanders and Colts at Tottenham Hotspur Stadium is scheduled to begin at 12:30am AEDT on Monday, October 5.

• Teams: Washington Commanders vs Indianapolis Colts
• Date: Monday 5 October 2026
• Time: 12:30am AEDT
• Venue: Tottenham Hotspur Stadium

All dates and times in this article are in Australian Eastern Daylight Time (AEDT), unless otherwise stated.

Conclusion

Our Washington vs Indianapolis predictions have been made based on 10,000 data-driven simulations of the game, carefully curated by our team of skilled data scientists and analysts. We use the latest in predictive analytics technology and machine learning to ensure our NFL tips are accurate and reliable, giving you the confidence to make informed decisions.

If you decide to use our predictions for betting purposes, it's crucial to gamble responsibly and manage your finances effectively. For free and confidential support, call 1800 858 858 or visit gamblinghelponline.org.au.

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