Colts vs Titans Prediction and Preview - NFL Week 8, 2025
Last updated: Oct 26, 2025, 8:25PM | Published: Oct 19, 2025, 4:01AM
The Indianapolis Colts will sqaure off with the Tennessee Titans in NFL Week 8 action at Lucas Oil Stadium on Monday, beginning at 7:25am AEDT.
This article features Stats Insider's prediction and tips for the Colts vs Titans game, as well as the latest betting odds and touchdown scorer tips.
Who Will Win?
Based on advanced machine learning and data, Stats Insider has simulated the outcome of Monday's Indianapolis vs Tennessee NFL match-up 10,000 times.
Our independent predictive analytics model currently gives the Colts a 90% chance of defeating the Titans in Week 8 of the NFL season.
Colts vs Titans: Odds
The current Bet365 betting odds in Australia for Monday's NFL game at Lucas Oil Stadium are shown below:
- Head to Head: Colts $1.06, Titans $10.00
- Line: Colts -15 ($1.91), Titans +15 ($1.91)
- Total (Over/Under 47.5 Points): Over $1.91, Under $1.91
Odds are correct at the time of publication and subject to change.
Looking at the latest head-to-head odds, Bet365 currently has the Colts at $1.06 and the Titans at $10.00.
The Colts are listed as 15-point favourites against the Titans, with odds of $1.91 available at Bet365.
For the underdog Titans (+15) to cover the line, Bet365 offers odds of $1.91.
The over/under for total points scored is set at 47.5 with Bet365, which has odds of $1.91 for the over and $1.91 for the under.
According to Stats Insider's model, the Titans (+15) are predicted to cover the line 51% of the time, while the 47.5-point over/under is expected to is considered an equal 50-50 chance of hitting.
Colts vs Titans: Betting Tips
- Head to Head: Tennessee at $10.00 with Bet365
- Line: Titans +15 at $1.91 with Bet365
- Total Points: Under 47.5 at $1.91 with Bet365
Today's Colts vs Titans betting tips are based on detailed modelling and gambling expertise to give you the best possible advice every time.
While the Colts have a higher chance of winning the game, betting on the Titans to win is our recommended option due to the edge found when comparing our data-driven probabilities to the odds currently on offer.
Making use of the edges seen here at Stats Insider is crucial to achieving long-term profitability.
Colts vs Titans: Prediction
Stats Insider's predicted final score for Colts vs Titans at Lucas Oil Stadium in Week 8 is the Colts winning 30-16.
This prediction is based on each team's average score from 10,000 game simulations.
Stats Insider provides full coverage of the Indianapolis vs Tennessee game in Week 8, including data-driven predictions and the best betting tips.
Get expert analysis from the US with Dimers' in-depth Colts vs Titans prediction.
18+. Odds correct at time of publishing and subject to change.Colts vs Titans: TD Scorer Tips
Who will score an anytime touchdown in Colts vs Titans? The latest data is in.
According to Stats Insider, Indianapolis' Jonathan Taylor is the most likely player to score the first touchdown in Colts vs Titans.
Taylor has a 21.3% chance of scoring the first TD at Lucas Oil Stadium, while the Colts RB has a 68.4% chance of registering an anytime touchdown.
Scroll down for the complete list of first touchdown scorer and anytime touchdown scorer probabilities.
First Touchdown Scorer Tips
Colts First TD Tips
- Jonathan Taylor: 21.3% probability
- Tyler Warren: 9.4% probability
- Michael Pittman: 6.7% probability
- Daniel Jones: 6.6% probability
- Josh Downs: 4.3% probability
Titans First TD Tips
- Tony Pollard: 6.6% probability
- Elic Ayomanor: 5.3% probability
- Tyjae Spears: 5.2% probability
- Chimere Dike: 3.9% probability
- Gunnar Helm: 3.2% probability
Anytime Touchdown Scorer Tips
Colts Anytime TD Tips
- Jonathan Taylor: 68.4% probability
- Tyler Warren: 39.8% probability
- Michael Pittman: 30.2% probability
- Daniel Jones: 30.2% probability
- Josh Downs: 20.9% probability
Titans Anytime TD Tips
- Tony Pollard: 28.4% probability
- Elic Ayomanor: 23.6% probability
- Tyjae Spears: 23.0% probability
- Chimere Dike: 18.0% probability
- Gunnar Helm: 15.0% probability
Colts-Titans Projected Player Stats
Of the starting quarterbacks, the Colts' Daniel Jones is projected for 240 passing yards, while the Titans' Cam Ward is expected to throw for 214 yards.
Colts Starting QB
- Daniel Jones: 240 projected passing yards
Titans Starting QB
- Cam Ward: 214 projected passing yards
Colts Rushing Yards
- Jonathan Taylor: 95 projected yards
- Daniel Jones: 17 projected yards
- Ameer Abdullah: 14 projected yards
Titans Rushing Yards
- Tony Pollard: 45 projected yards
- Tyjae Spears: 24 projected yards
- Cam Ward: 10 projected yards
Colts Receiving Yards
- Tyler Warren: 58 projected yards
- Michael Pittman: 56 projected yards
- Alec Pierce: 44 projected yards
- Josh Downs: 42 projected yards
- Jonathan Taylor: 22 projected yards
Titans Receiving Yards
- Elic Ayomanor: 43 projected yards
- Van Jefferson: 36 projected yards
- Chimere Dike: 35 projected yards
- Chig Okonkwo: 32 projected yards
- Gunnar Helm: 26 projected yards
Remember, our model updates frequently, so refresh this article for the latest betting tips before the Indianapolis vs Tennessee game.
As always, see Stats Insider's Best Bets for betting tips on every NFL game, plus predictions for a wide range of other sports.
Colts vs Titans: Week 8 Essential Details
The NFL Week 8 match-up between the Colts and Titans at Lucas Oil Stadium is scheduled to begin at 7:25am AEDT on Monday.
- Teams: Indianapolis Colts vs Tennessee Titans
- Date: Monday 27 October 2025
- Time: 7:25am AEDT
- Venue: Lucas Oil Stadium
All dates and times mentioned in this article are in Australian Eastern Daylight Time (AEDT), unless otherwise noted.
Conclusion
Our Indianapolis vs Tennessee predictions are based on 10,000 data-driven simulations of the game, carefully curated by our team of experienced data scientists and analysts. We use the latest in predictive analytics technology and machine learning to ensure our NFL tips are trustworthy and reliable, giving you the confidence to make informed decisions.
If you decide to use our predictions for betting purposes, it's important that you gamble responsibly and keep track of your money. For free and confidential support, call 1800 858 858 or visit gamblinghelponline.org.au.
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