Colts vs Titans Prediction and Preview - NFL Week 8, 2025
Last updated: Oct 20, 2025, 7:40AM | Published: Oct 19, 2025, 4:01AM
The Indianapolis Colts will take on the Tennessee Titans in NFL Week 8 action at Lucas Oil Stadium on Monday, commencing at 7:25am AEDT.
This article features Stats Insider's best betting tips for the Colts vs Titans game, as well as the latest betting odds in Australia.
Who Will Win?
Utilising advanced machine learning and data, Stats Insider has simulated the result of Monday's Indianapolis vs Tennessee NFL game 10,000 times.
Our independent predictive analytics model gives the Colts a 62% chance of winning against the Titans in Week 8 of the NFL season.
Colts vs Titans: Odds
The current Bet365 betting odds in Australia for Monday's NFL game at Lucas Oil Stadium are listed below:
- Head to Head: Colts $1.10, Titans $7.50
- Line: Colts -14 ($1.91), Titans +14 ($1.91)
- Total (Over/Under 46.5 Points): Over $1.91, Under $1.91
Odds are correct at the time of publication and subject to change.
Looking at the latest head-to-head odds, Bet365 currently has the Colts at $1.10 and the Titans at $7.50.
The Colts are 14-point favourites against the Titans, with odds of $1.91 available at Bet365.
For the underdog Titans (+14) to cover the line, Bet365 offers odds of $1.91.
The over/under for total points scored is set at 46.5 with Bet365, which has odds of $1.91 for the over and $1.91 for the under.
According to Stats Insider's analytics model, the Titans (+14) are predicted to cover the line 94% of the time, while the 46.5-point over/under is expected to stay under 55% of the time.
Colts vs Titans: Betting Tips
- Head to Head: Tennessee at $7.50 with Bet365
- Line: Titans +14 at $1.91 with Bet365
- Total Points: Under 46.5 at $1.91 with Bet365
When you see a 🔥, you know it's one of our best bets of the day across any sport.
Today's Colts vs Titans betting tips are based on complex modelling and wagering experience to provide you with the best possible advice 24/7/365.
While the Colts have a higher chance of winning the game, betting on the Titans to win is our recommended option because of the 24.7% edge identified when comparing our data-driven probabilities to the odds currently available.
Making use of the edges published on Stats Insider is pivotal to achieving long-term profitability.
Colts vs Titans: Prediction
Stats Insider's predicted final score for Colts vs Titans at Lucas Oil Stadium in Week 8 is the Colts winning 23-20.
This prediction is based on each team's average score following 10,000 game simulations.
Stats Insider provides full betting coverage of the Indianapolis vs Tennessee game in Week 8, including data-driven predictions and live win probabilitiestips.
18+. Odds correct at time of publishing and subject to change.Our model updates regularly, so bookmark this page for the latest betting predictions before the Indianapolis vs Tennessee match-up.
As always, see Stats Insider's Best Bets for betting tips on every NFL game, plus predictions for a wide range of other sports.
Colts vs Titans: Week 8 Essential Details
The NFL Week 8 match-up between the Colts and Titans at Lucas Oil Stadium is scheduled to start at 7:25am AEDT on Monday.
- Teams: Indianapolis Colts vs Tennessee Titans
- Date: Monday 27 October 2025
- Time: 7:25am AEDT
- Venue: Lucas Oil Stadium
All dates and times in this article are in Australian Eastern Daylight Time (AEDT), unless otherwise noted.
Conclusion
Our Indianapolis vs Tennessee predictions have been made thanks to 10,000 data-driven simulations of the game, all curated by our team of experienced data scientists and analysts. We use the latest in predictive analytics technology and machine learning to ensure our NFL tips are accurate and reliable, giving you the confidence to make informed decisions.
If you decide to use our NFL predictions for betting purposes, it's important to gamble responsibly and manage your finances effectively. For free and confidential support, call 1800 858 858 or visit gamblinghelponline.org.au.
More on NFL
Stats Insider is your go-to source for betting on the NFL in Australia, with the latest NFL betting news, tips for every NFL game, and Super Bowl probabilities for the NFL.
