Colts vs Dolphins Prediction and Preview - NFL Week 1, 2025

The Indianapolis Colts will sqaure off with the Miami Dolphins in NFL Week 1 action at Lucas Oil Stadium on Monday, September 8, starting at 3:00am AEST.

This article features Stats Insider's top betting tips for the Colts vs Dolphins game, along with the latest betting odds in Australia.

Who Will Win?

Using advanced computer power and data, Stats Insider has simulated the outcome of Dolphins vs Colts 10,000 times.

Our independent predictive analytics model currently gives the Colts a 55% chance of beating the Dolphins at Lucas Oil Stadium.

Colts vs Dolphins: Odds

The current Bet365 betting odds in Australia for this NFL game at Lucas Oil Stadium are shown here:

• Head to Head: Colts $1.80, Dolphins $2.05
• Line: Colts -1.5 ($1.91), Dolphins +1.5 ($1.91)
• Total (Over/Under 47 Points): Over $1.91, Under $1.91

Odds are correct at the time of publication and subject to change.

Looking at the latest head-to-head odds, Bet365 currently has the Colts at $1.80 and the Dolphins at $2.05.

The Colts are listed as 1.5-point favourites against the Dolphins, with odds of $1.91 available at Bet365.

For the underdog Dolphins (+1.5) to cover the line, Bet365 offers odds of $1.91.

The over/under for total points scored is set at 47 with Bet365, which has odds of $1.91 for the over and $1.91 for the under.

According to Stats Insider's analytics model, the bookmakers have got it right and both the Colts and the Dolphins have a 50% chance of covering the line.

The 47-point over/under is expected to stay under 52% of the time.

Colts vs Dolphins: Best Bets

• Head to Head: Indianapolis at $1.80 with Bet365
• Line: Dolphins +1.5 at $1.91 with Bet365
• Total Points: Under 47 at $1.91 with Bet365

Our Colts vs Dolphins best bets are based on market-leading simulations and gambling intelligence to help you place smarter bets with your chosen online bookie.

Colts vs Dolphins: Prediction

Stats Insider's predicted final score for Colts vs Dolphins at Lucas Oil Stadium in Week 1 is the Colts winning 23-22.

This prediction is based on each team's average score following 10,000 game simulations.

Stats Insider provides full coverage of the Indianapolis vs Miami game in Week 1, including data-driven predictions and the best betting tips.

Our model updates regularly, so refresh this page for the latest betting analysis before the Indianapolis vs Miami game.

As always, see Stats Insider's Best Bets to get the best tips for every NFL game, plus predictions for a wide range of other sports.

Colts vs Dolphins: Week 1 Essential Details

The NFL Week 1 match-up between the Colts and Dolphins at Lucas Oil Stadium is scheduled to commence at 3:00am AEST on Monday, September 8.

• Teams: Indianapolis Colts vs Miami Dolphins
• Date: Monday 8 September 2025
• Time: 3:00am AEST
• Venue: Lucas Oil Stadium

All dates and times in this article are in Australian Eastern Standard Time (AEST), unless otherwise noted.

Conclusion

Our Indianapolis vs Miami predictions are the result of 10,000 data-driven simulations of the game, carefully curated by our team of expert data scientists and analysts. We use cutting-edge technology and machine learning to ensure our NFL tips are accurate and reliable, giving you the confidence to make informed decisions.

If you choose to use our predictions for betting purposes, it's crucial that you gamble responsibly and manage your finances effectively. For free and confidential support, call 1800 858 858 or visit gamblinghelponline.org.au.

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