Chiefs vs Colts Prediction and Preview - NFL Week 12, 2025
Last updated: Nov 16, 2025, 9:16AM | Published: Nov 16, 2025, 5:01AM
The Kansas City Chiefs will sqaure off with the Indianapolis Colts in NFL Week 12 action at GEHA Field at Arrowhead Stadium on Monday, November 24, starting at 5:00am AEDT.
This article features Stats Insider's best betting tips for the Chiefs vs Colts game, as well as the latest betting odds in Australia.
Who Will Win?
Using advanced machine learning and data, Stats Insider has simulated the outcome of Colts vs Chiefs 10,000 times.
Our independent predictive analytics model currently gives the Chiefs a 77% chance of defeating the Colts in Week 12 of the NFL season.
Chiefs vs Colts: Odds
The current Bet365 betting odds in Australia for this NFL game at GEHA Field at Arrowhead Stadium are shown below:
- Head to Head: Chiefs $1.50, Colts $2.65
- Line: Chiefs -3.5 ($1.91), Colts +3.5 ($1.91)
- Total (Over/Under 50.5 Points): Over $1.91, Under $1.91
Odds are correct at the time of publication and subject to change.
Looking at the latest head-to-head odds, Bet365 currently has the Chiefs at $1.50 and the Colts at $2.65.
The Chiefs are listed as 3.5-point favourites against the Colts, with odds of $1.91 available at Bet365.
For the underdog Colts (+3.5) to cover the line, Bet365 offers odds of $1.91.
The over/under for total points scored is set at 50.5 with Bet365, which has odds of $1.91 for the over and $1.91 for the under.
According to Stats Insider's model, the Chiefs (-3.5) are predicted to cover the line 74% of the time, while the 50.5-point over/under is expected to stay under 70% of the time.
Chiefs vs Colts: Betting Tips
- Head to Head: Kansas City at $1.50 with Bet365
- Line: Chiefs -3.5 at $1.91 with Bet365
- Total Points: Under 50.5 at $1.91 with Bet365
When you see a 🔥, that means it's one of our best bets for today across all sports.
Our Chiefs vs Colts betting tips are based on market-leading modelling and wagering intelligence to provide you with the best possible advice 24/7.
Chiefs vs Colts: Prediction
Stats Insider's predicted final score for Chiefs vs Colts at GEHA Field at Arrowhead Stadium in Week 12 is the Chiefs winning 25-18.
This prediction is based on each team's average score following 10,000 game simulations.
Stats Insider provides full coverage of the Kansas City vs Indianapolis game in Week 12, including data-driven predictions and live win probabilitiestips.
18+. Odds correct at time of publishing and subject to change.Remember, our model updates frequently, so keep checking this page for the latest betting tips before the Kansas City vs Indianapolis match-up.
As always, see our Best Bets for the best tips on every NFL game, as well as predictions for a wide range of other sports.
Chiefs vs Colts: Week 12 Essential Details
The NFL Week 12 game between the Chiefs and Colts at GEHA Field at Arrowhead Stadium is scheduled to commence at 5:00am AEDT on Monday, November 24.
- Teams: Kansas City Chiefs vs Indianapolis Colts
- Date: Monday 24 November 2025
- Time: 5:00am AEDT
- Venue: GEHA Field at Arrowhead Stadium
All dates and times mentioned in this article are in Australian Eastern Daylight Time (AEDT), unless otherwise noted.
Conclusion
Our Kansas City vs Indianapolis predictions are the result of 10,000 data-driven simulations of the game, all curated by our team of experienced data scientists and analysts. We use cutting-edge technology and machine learning to ensure our NFL tips are accurate and reliable, giving you the confidence to make informed decisions.
If you decide to use our NFL predictions for betting purposes, it's vital to gamble responsibly and manage your finances effectively. For free and confidential support, call 1800 858 858 or visit gamblinghelponline.org.au.
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