Chargers vs Colts Prediction and Preview - NFL Week 7, 2025
Last updated: Oct 19, 2025, 7:55PM | Published: Oct 14, 2025, 8:13PM
The Los Angeles Chargers will take on the Indianapolis Colts in NFL Week 7 action at SoFi Stadium on Monday, commencing at 7:05am AEDT.
This article features Stats Insider's best betting tips for the Chargers vs Colts game, plus the latest betting odds and touchdown scorer tips.
Who Will Win?
Based on trusted machine learning and data, Stats Insider has simulated the outcome of Monday's LA Chargers vs Indianapolis NFL game 10,000 times.
Our proven predictive analytics model gives the Chargers a 57% chance of winning against the Colts at SoFi Stadium.
Chargers vs Colts: Odds
The latest Bet365 betting odds in Australia for Monday's NFL game at SoFi Stadium are shown below:
- Head to Head: Chargers $1.67, Colts $2.25
- Line: Chargers -2.5 ($1.91), Colts +2.5 ($1.91)
- Total (Over/Under 48.5 Points): Over $1.91, Under $1.91
Odds are correct at the time of publication and subject to change.
Looking at the latest head-to-head odds, Bet365 currently has the Chargers at $1.67 and the Colts at $2.25.
The Chargers are 2.5-point favourites against the Colts, with odds of $1.91 available at Bet365.
For the underdog Colts (+2.5) to cover the line, Bet365 offers odds of $1.91.
The over/under for total points scored is set at 48.5 with Bet365, which has odds of $1.91 for the over and $1.91 for the under.
According to Stats Insider's model, the Colts (+2.5) are predicted to cover the line 58% of the time, while the 48.5-point over/under is expected to is considered an equal 50-50 chance of hitting.
Chargers vs Colts: Betting Tips
- Head to Head: Indianapolis at $2.25 with Bet365
- Line: Colts +2.5 at $1.91 with Bet365
- Total Points: Under 48.5 at $1.91 with Bet365
When you see a 🔥, you know it's one of Stats Insider's best bets for today across all sports.
Our Chargers vs Colts betting tips are based on detailed simulations and betting expertise to bring you the best possible advice every time.
While the Chargers have a higher chance of winning the game, betting on the Colts to win is our preferred option because of the edge found when comparing our data-driven probabilities to the odds currently on offer.
Making use of the edges seen on Stats Insider is one of the keys to being profitable in the long run.
Chargers vs Colts: Prediction
Stats Insider's predicted final score for Chargers vs Colts at SoFi Stadium in Week 7 is the Chargers winning 25-23.
This prediction is based on each team's average score following 10,000 game simulations.
Stats Insider provides full betting coverage of the LA Chargers vs Indianapolis game in Week 7, including data-driven predictions and expert tips.
For in-depth analysis from US experts,, check out Dimers' detailed Chargers vs Colts prediction.
18+. Odds correct at time of publishing and subject to change.Chargers vs Colts: TD Scorer Tips
Who will score an anytime touchdown in Chargers vs Colts? The latest data is in.
According to Stats Insider, Indianapolis' Jonathan Taylor is the most likely player to score the first touchdown in Chargers vs Colts.
Taylor has a 15.4% chance of scoring the first TD at SoFi Stadium, while the Colts RB has a 58.6% chance of scoring an anytime touchdown.
Scroll down for the complete list of first touchdown scorer and anytime touchdown scorer probabilities.
First Touchdown Scorer Tips
Chargers First TD Tips
- Kimani Vidal: 9.2% probability
- Hassan Haskins: 7.4% probability
- Quentin Johnston: 7.3% probability
- Keenan Allen: 6.9% probability
- Ladd McConkey: 6.8% probability
Colts First TD Tips
- Jonathan Taylor: 15.4% probability
- Tyler Warren: 7.0% probability
- Michael Pittman: 5.7% probability
- Daniel Jones: 5.7% probability
- Alec Pierce: 3.9% probability
Anytime Touchdown Scorer Tips
Chargers Anytime TD Tips
- Kimani Vidal: 40.3% probability
- Hassan Haskins: 33.8% probability
- Quentin Johnston: 33.6% probability
- Keenan Allen: 32.1% probability
- Ladd McConkey: 31.8% probability
Colts Anytime TD Tips
- Jonathan Taylor: 58.6% probability
- Tyler Warren: 33.2% probability
- Michael Pittman: 28.1% probability
- Daniel Jones: 28.0% probability
- Alec Pierce: 20.2% probability
Chargers-Colts Projected Player Stats
Of the starting quarterbacks, the Chargers' Justin Herbert is projected for 268 passing yards, while the Colts' Daniel Jones is expected to throw for 227 yards.
Chargers Starting QB
- Justin Herbert: 268 projected passing yards
Colts Starting QB
- Daniel Jones: 227 projected passing yards
Chargers Rushing Yards
- Kimani Vidal: 57 projected yards
- Hassan Haskins: 23 projected yards
- Justin Herbert: 19 projected yards
Colts Rushing Yards
- Jonathan Taylor: 87 projected yards
- Daniel Jones: 22 projected yards
- DJ Giddens: 11 projected yards
Chargers Receiving Yards
- Ladd McConkey: 66 projected yards
- Quentin Johnston: 62 projected yards
- Keenan Allen: 55 projected yards
- Oronde Gadsden: 32 projected yards
- Kimani Vidal: 19 projected yards
Colts Receiving Yards
- Tyler Warren: 58 projected yards
- Michael Pittman: 57 projected yards
- Alec Pierce: 46 projected yards
- Adonai Mitchell: 30 projected yards
- Jonathan Taylor: 22 projected yards
Remember, our model updates regularly, so keep checking this page for the latest betting analysis before the LA Chargers vs Indianapolis match-up.
As always, see Stats Insider's Best Bets to get the best tips on every NFL game, as well as predictions for a wide range of other sports.
Chargers vs Colts: Week 7 Essential Details
The NFL Week 7 match-up between the Chargers and Colts at SoFi Stadium is scheduled to begin at 7:05am AEDT on Monday.
- Teams: Los Angeles Chargers vs Indianapolis Colts
- Date: Monday 20 October 2025
- Time: 7:05am AEDT
- Venue: SoFi Stadium
All dates and times mentioned in this article are in Australian Eastern Daylight Time (AEDT), unless otherwise stated.
Conclusion
Our LA Chargers vs Indianapolis predictions are the result of 10,000 data-driven simulations of the game, all curated by our team of skilled data scientists and analysts. We use the latest in predictive analytics technology and machine learning to ensure our NFL tips are trustworthy and reliable, giving you the confidence to make informed decisions.
If you choose to use our predictions for betting purposes, it's important to gamble responsibly and know when to stop. For free and confidential support, call 1800 858 858 or visit gamblinghelponline.org.au.
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