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Cardinals vs Yankees Prediction and MLB Tips - 18 August 2025

The St. Louis Cardinals will take on the New York Yankees in MLB action at Busch Stadium on Monday, starting at 4:15am AEST.

The Cardinals will have Miles Mikolas (6-9, 4.97 ERA) start, up against Will Warren (7-5, 4.34 ERA) for the Yankees.

This article features Stats Insider's free betting tips for the Cardinals vs Yankees game, plus the latest betting odds in Australia.

Who Will Win?

Utilising advanced computer power and data, Stats Insider has simulated the result of Monday's St. Louis vs NY Yankees MLB match-up 10,000 times.

Our independent predictive analytics model gives the Yankees a 58% chance of defeating the Cardinals at Busch Stadium.

Cardinals vs Yankees: Odds

The latest betting odds in Australia for Monday's MLB game at Busch Stadium are listed here:

  • Head to Head: Cardinals $2.35, Yankees $1.62
  • Line: Cardinals +1.5 ($1.83), Yankees -1.5 ($2.00)
  • Total (Over/Under 9 Runs): Over $1.91, Under $1.91

Odds are correct at the time of publication and subject to change.

Looking at the latest head-to-head odds, the bookmakers currently have the Cardinals at $2.35 and the Yankees at $1.62.

The Cardinals are 1.5-run underdogs against the Yankees, with odds of $1.83 available at TAB.

For the favourite Yankees (-1.5) to cover the line, TAB offers odds of $2.00.

The over/under for total runs scored is set at 9 with TAB, which has odds of $1.91 for the over and $1.91 for the under.

According to Stats Insider's analytics model, the Cardinals (+1.5) are predicted to cover the line 54% of the time, while the 9-run over/under is expected to stay under 55% of the time.

Cardinals vs Yankees: Betting Tips

  • Head to Head: St. Louis at $2.35 with TAB
  • Line: Cardinals +1.5 at $1.83 with TAB
  • Total Runs: Under 9 at $1.91 with TAB

Our Cardinals vs Yankees betting tips are based on detailed modelling and gambling experience to help you place more informed bets with your chosen online bookie.

While the Yankees have a higher chance of winning the game, betting on the Cardinals to win is our recommended option because of the 1.1% edge identified when comparing our data-driven probabilities to the odds currently on offer.

Taking advantage of the edges seen on Stats Insider is one of the keys to being a profitable sports bettor in the long run.

Cardinals vs Yankees: Prediction

Stats Insider provides full betting coverage of the St. Louis vs NY Yankees game on Monday, including data-driven predictions and live win probabilitiestips.

Our model updates regularly, so refresh this page for the latest betting tips before the St. Louis vs NY Yankees game.

As always, see Stats Insider's Best Bets for the best tips on every MLB game, as well as predictions for a wide range of other sports.

Cardinals vs Yankees: Essential Details

The match-up between the Cardinals and Yankees at Busch Stadium is scheduled to begin at 4:15am AEST on Monday.

All dates and times in this article are in Australian Eastern Standard Time (AEST), unless otherwise stated.

Conclusion

Our St. Louis vs NY Yankees predictions have been made thanks to 10,000 data-driven simulations of the game, carefully curated by our team of experienced data scientists and analysts. We use cutting-edge technology and machine learning to ensure our MLB tips are trustworthy and reliable, giving you the confidence to make informed decisions.

If you choose to use our MLB predictions for betting purposes, it's vital to gamble responsibly and keep track of your money. For free and confidential support, call 1800 858 858 or visit gamblinghelponline.org.au.

More on MLB

Stats Insider is your go-to source for betting on the MLB in Australia, with the latest MLB betting news, tips for every MLB game, and futures probabilities for the MLB.

Stats Insider

Stats Insider, Australia's leading predictive analytics website, offers Australian sports fans innovative tools and content to enhance their enjoyment of major sporting events both domestically and internationally. Our goal is to transform the sports fan experience by providing readily accessible, data-driven content for sports enthusiasts like us.

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