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Cardinals vs Yankees Prediction and MLB Tips - 16 August 2025

The St. Louis Cardinals will take on the New York Yankees in MLB action at Busch Stadium on Saturday, beginning at 10:15am AEST.

Andre Pallante (6-9, 4.95 ERA) will start for the Cardinals, while the Yankees will counter with Luis Gil (0-1, 7.27 ERA).

This article features Stats Insider's prediction and tips for the Cardinals vs Yankees game, plus the latest betting odds in Australia.

Who Will Win?

Utilising advanced computer power and data, Stats Insider has simulated the outcome of Saturday's St. Louis vs NY Yankees MLB game 10,000 times.

Our independent predictive analytics model currently gives the Yankees a 56% chance of beating the Cardinals at Busch Stadium.

Cardinals vs Yankees: Odds

The latest betting odds in Australia for Saturday's MLB game at Busch Stadium are shown below:

  • Head to Head: Cardinals $2.25, Yankees $1.67
  • Line: Cardinals +1.5 ($1.74), Yankees -1.5 ($2.14)
  • Total (Over/Under 9 Runs): Over $1.91, Under $1.91

Odds are correct at the time of publication and subject to change.

Looking at the latest head-to-head odds, the bookmakers currently have the Cardinals at $2.25 and the Yankees at $1.67.

The Cardinals are listed as 1.5-run underdogs against the Yankees, with odds of $1.74 available at TAB.

For the favourite Yankees (-1.5) to cover the line, TAB offers odds of $2.14.

The over/under for total runs scored is set at 9 with TAB, which has odds of $1.91 for the over and $1.91 for the under.

According to Stats Insider's analytics model, the Cardinals (+1.5) are predicted to cover the line 57% of the time, while the 9-run over/under is expected to stay under 56% of the time.

Cardinals vs Yankees: Best Bets

  • Head to Head: St. Louis at $2.25 with TAB
  • Line: Cardinals +1.5 at $1.74 with TAB
  • Total Runs: Under 9 at $1.91 with TAB

Today's Cardinals vs Yankees best bets are based on market-leading simulations and wagering intelligence to bring you the best possible advice every time.

While the Yankees have a higher chance of winning the game, betting on the Cardinals to win is our recommended option because of the 1.4% edge identified when comparing our data-driven probabilities to the odds currently available.

Making use of the edges seen here at Stats Insider is pivotal to achieving long-term success as a sports bettor.

Cardinals vs Yankees: Prediction

Stats Insider provides full betting coverage of the St. Louis vs NY Yankees game on Saturday, including data-driven predictions and free tips.

Our model updates regularly, so bookmark this page for the latest betting predictions before the St. Louis vs NY Yankees game.

As always, see our Best Bets to get betting tips on every MLB game, as well as predictions for a wide range of other sports.

Cardinals vs Yankees: Essential Details

The game between the Cardinals and Yankees at Busch Stadium is scheduled to start at 10:15am AEST on Saturday.

All dates and times in this article are in Australian Eastern Standard Time (AEST), unless otherwise noted.

Conclusion

Our St. Louis vs NY Yankees predictions are based on 10,000 data-driven simulations of the game, all curated by our team of skilled data scientists and analysts. We use the latest in predictive analytics technology and machine learning to ensure our MLB tips are accurate and reliable, giving you the confidence to make informed decisions.

If you choose to use our MLB predictions for betting purposes, it's crucial to gamble responsibly and manage your finances effectively. For free and confidential support, call 1800 858 858 or visit gamblinghelponline.org.au.

More on MLB

Stats Insider is your go-to source for betting on the MLB in Australia, with the latest MLB betting news, predictions for every MLB game, and futures odds for the MLB.

Stats Insider

Stats Insider, Australia's leading predictive analytics website, offers Australian sports fans innovative tools and content to enhance their enjoyment of major sporting events both domestically and internationally. Our goal is to transform the sports fan experience by providing readily accessible, data-driven content for sports enthusiasts like us.

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