Cardinals vs Titans Prediction and Preview - NFL Week 5, 2025
Last updated: Sep 30, 2025, 6:52AM | Published: Sep 28, 2025, 4:00AM
The Arizona Cardinals will face the Tennessee Titans in NFL Week 5 action at State Farm Stadium on Monday, commencing at 7:05am AEDT.
This article features Stats Insider's prediction and tips for the Cardinals vs Titans game, plus the latest betting odds and touchdown scorer tips.
Who Will Win?
Utilising trusted computer power and data, Stats Insider has simulated the outcome of Monday's Arizona vs Tennessee NFL game 10,000 times.
Our leading predictive analytics model gives the Cardinals a 79% chance of beating the Titans at State Farm Stadium.
Cardinals vs Titans: Odds
The current Bet365 betting odds in Australia for Monday's NFL game at State Farm Stadium are listed below:
- Head to Head: Cardinals $1.20, Titans $4.75
- Line: Cardinals -8.5 ($1.91), Titans +8.5 ($1.91)
- Total (Over/Under 41.5 Points): Over $1.91, Under $1.91
Odds are correct at the time of publication and subject to change.
Looking at the latest head-to-head odds, Bet365 currently has the Cardinals at $1.20 and the Titans at $4.75.
The Cardinals are listed as 8.5-point favourites against the Titans, with odds of $1.91 available at Bet365.
For the underdog Titans (+8.5) to cover the line, Bet365 offers odds of $1.91.
The over/under for total points scored is set at 41.5 with Bet365, which has odds of $1.91 for the over and $1.91 for the under.
According to Stats Insider's analytics model, the Titans (+8.5) are predicted to cover the line 52% of the time, while the 41.5-point over/under is expected to is considered an equal 50-50 chance of hitting.
Cardinals vs Titans: Best Bets
- Head to Head: Tennessee at $4.75 with Bet365
- Line: Titans +8.5 at $1.91 with Bet365
- Total Points: Under 41.5 at $1.91 with Bet365
Stats Insider's Cardinals vs Titans predictions are based on world-class modelling and gambling expertise to bring you the best possible advice 24/7.
While the Cardinals have a higher chance of winning the game, betting on the Titans to win is our recommended option due to the edge found when comparing our data-led probabilities to the odds currently on offer.
Taking advantage of the edges seen here at Stats Insider is crucial to being a profitable punter in the long run.
Cardinals vs Titans: Prediction
Stats Insider's predicted final score for Cardinals vs Titans at State Farm Stadium in Week 5 is the Cardinals winning 24-16.
This prediction is based on each team's average score following 10,000 game simulations.
Stats Insider provides full betting coverage of the Arizona vs Tennessee game in Week 5, including data-driven predictions and free betting tips.
18+. Odds correct at time of publishing and subject to change.Cardinals vs Titans: TD Scorer Tips
Who will score the first touchdown in Cardinals vs Titans? The data is in.
According to Stats Insider, Arizona's Marvin Harrison is the most likely player to score the first TD in Cardinals vs Titans.
Harrison has an 11.4% chance of scoring the first TD at State Farm Stadium, while the Cardinals WR has a 33.0% chance of scoring an anytime touchdown.
Scroll down for our full list of first touchdown scorer and anytime touchdown scorer probabilities.
First Touchdown Scorer Tips
Cardinals First TD Tips
- Marvin Harrison: 11.4% probability
- Trey McBride: 9.1% probability
- Trey Benson: 8.6% probability
- Emari Demercado: 7.9% probability
- Kyler Murray: 6.3% probability
Titans First TD Tips
- Elic Ayomanor: 8.0% probability
- Tony Pollard: 6.7% probability
- Calvin Ridley: 6.0% probability
- Tyjae Spears: 5.6% probability
- Chig Okonkwo: 3.1% probability
Anytime Touchdown Scorer Tips
Cardinals Anytime TD Tips
- Marvin Harrison: 33.0% probability
- Trey McBride: 27.2% probability
- Trey Benson: 26.1% probability
- Emari Demercado: 24.2% probability
- Kyler Murray: 19.9% probability
Titans Anytime TD Tips
- Elic Ayomanor: 33.1% probability
- Tony Pollard: 28.6% probability
- Calvin Ridley: 26.0% probability
- Tyjae Spears: 24.4% probability
- Chig Okonkwo: 14.7% probability
Cardinals-Titans Projected Player Stats
Of the starting quarterbacks, the Cardinals' Kyler Murray is projected for 213 passing yards. The Titans' Cam Ward is expected to throw for 185 yards.
Cardinals Starting QB
- Kyler Murray: 213 projected passing yards
Titans Starting QB
- Cam Ward: 185 projected passing yards
Cardinals Rushing Yards
- Trey Benson: 62 projected yards
- Kyler Murray: 26 projected yards
- Emari Demercado: 26 projected yards
Titans Rushing Yards
- Tony Pollard: 61 projected yards
- Tyjae Spears: 25 projected yards
- Cam Ward: 12 projected yards
Cardinals Receiving Yards
- Trey McBride: 59 projected yards
- Marvin Harrison: 56 projected yards
- Michael Wilson: 25 projected yards
- Zay Jones: 13 projected yards
- Trey Benson: 13 projected yards
Titans Receiving Yards
- Calvin Ridley: 47 projected yards
- Elic Ayomanor: 41 projected yards
- Chig Okonkwo: 28 projected yards
- Chimere Dike: 15 projected yards
- Tyler Lockett: 12 projected yards
Remember, our model updates regularly, so bookmark this page for the latest betting predictions before the Arizona vs Tennessee match-up.
As always, see Stats Insider's Best Bets for the best tips on every NFL game, as well as predictions for a wide range of other sports.
Cardinals vs Titans: Week 5 Essential Details
The NFL Week 5 match-up between the Cardinals and Titans at State Farm Stadium is scheduled to start at 7:05am AEDT on Monday.
- Teams: Arizona Cardinals vs Tennessee Titans
- Date: Monday 6 October 2025
- Time: 7:05am AEDT
- Venue: State Farm Stadium
All dates and times mentioned in this article are in Australian Eastern Daylight Time (AEDT), unless otherwise noted.
Conclusion
Our Arizona vs Tennessee predictions are the result of 10,000 data-driven simulations of the game, all curated by our team of expert data scientists and analysts. We use cutting-edge technology and machine learning to ensure our NFL tips are trustworthy and reliable, giving you the knowledge you need to make informed decisions with confidence.
If you choose to use our predictions for betting purposes, it's vital that you gamble responsibly and keep track of your money. For free and confidential support, call 1800 858 858 or visit gamblinghelponline.org.au.
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