Cardinals vs Tigers Prediction and MLB Tips - 22 May 2025
Last updated: May 21, 2025, 5:15PM | Published: May 21, 2025, 3:28AM
The St. Louis Cardinals will take on the Detroit Tigers in MLB action at Busch Stadium on Thursday, beginning at 3:15am AEST.
The Cardinals will send Andre Pallante (4-2, 4.11 ERA) to the mound, while the Tigers are going with Brant Hurter (1-0, 2.35 ERA).
This article features Stats Insider's prediction and tips for the Cardinals vs Tigers game, along with the latest betting odds in Australia.
Who Will Win?
Using trusted machine learning and data, Stats Insider has simulated the result of Thursday's St. Louis vs Detroit MLB game 10,000 times.
Our proven predictive analytics model currently gives the Cardinals a 53% chance of defeating the Tigers at Busch Stadium.
Cardinals vs Tigers: Odds
The current betting odds in Australia for Thursday's MLB game at Busch Stadium are listed here:
- Head to Head: Cardinals $1.83, Tigers $2.00
- Line: Cardinals -1.5 ($2.75), Tigers +1.5 ($1.48)
- Total (Over/Under 8.5 Runs): Over $1.91, Under $1.91
Odds are correct at the time of publication and subject to change.
Looking at the latest head-to-head odds, the bookmakers currently have the Cardinals at $1.83 and the Tigers at $2.00.
The Cardinals are 1.5-run favourites against the Tigers, with odds of $2.75 available at TAB.
For the underdog Tigers (+1.5) to cover the line, TAB offers odds of $1.48.
The over/under for total runs scored is set at 8.5 with TAB, which has odds of $1.91 for the over and $1.91 for the under.
According to Stats Insider's analytics model, the Tigers (+1.5) are predicted to cover the line 64% of the time, while the 8.5-run over/under is expected to stay under 52% of the time.
Cardinals vs Tigers: Best Bets
- Head to Head: St. Louis at $1.83 with TAB
- Line: Cardinals -1.5 at $2.75 with TAB
- Total Runs: Under 8.5 at $1.91 with TAB
These Cardinals vs Tigers best bets are based on detailed modelling and betting intelligence to help you place smarter bets with your chosen online bookie.
Although the Tigers are more likely to cover the line, our best bet of Cardinals -1.5 is based on the chance of that happening, as suggested by our predictive analytics model, and the best odds available.
Cardinals vs Tigers: Prediction
Stats Insider provides full coverage of the St. Louis vs Detroit game on Thursday, including data-driven predictions and free betting tips.
Our model updates regularly, so keep checking this page for the latest betting analysis before the St. Louis vs Detroit match-up.
As always, see Stats Insider's Best Bets for betting tips for every MLB game, as well as predictions for a wide range of other sports.
Cardinals vs Tigers: Essential Details
The match-up between the Cardinals and Tigers at Busch Stadium is scheduled to start at 3:15am AEST on Thursday.
- Teams: St. Louis Cardinals vs Detroit Tigers
- Date: Thursday 22 May 2025
- Time: 3:15am AEST
- Venue: Busch Stadium
All dates and times in this article are in Australian Eastern Standard Time (AEST), unless otherwise stated.
Conclusion
Our St. Louis vs Detroit predictions have been made thanks to 10,000 data-driven simulations of the game, all curated by our team of expert data scientists and analysts. We use the latest in predictive analytics technology and machine learning to ensure our MLB tips are accurate and reliable, so that you can make informed decisions with confidence.
If you choose to use our MLB predictions for betting purposes, it's vital that you gamble responsibly and know when to stop. For free and confidential support, call 1800 858 858 or visit gamblinghelponline.org.au.
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