Cardinals vs Tigers Prediction and MLB Tips - 21 May 2025
Last updated: May 20, 2025, 11:46PM | Published: May 19, 2025, 6:29PM
The St. Louis Cardinals will face the Detroit Tigers in MLB action at Busch Stadium on Wednesday, commencing at 9:45am AEST.
The Cardinals will send Erick Fedde (3-3, 3.44 ERA) to the mound, while the Tigers are going with Tarik Skubal (4-2, 2.67 ERA).
This article features Stats Insider's top betting tips for the Cardinals vs Tigers game, along with the latest betting odds in Australia.
Who Will Win?
Utilising trusted computer power and data, Stats Insider has simulated the result of Wednesday's St. Louis vs Detroit MLB game 10,000 times.
Our leading predictive analytics model currently gives the Tigers a 59% chance of beating the Cardinals at Busch Stadium.
Cardinals vs Tigers: Odds
The latest betting odds in Australia for Wednesday's MLB game at Busch Stadium are shown here:
- Head to Head: Cardinals $2.50, Tigers $1.56
- Line: Cardinals +1.5 ($1.85), Tigers -1.5 ($1.98)
- Total (Over/Under 7.5 Runs): Over $1.91, Under $1.91
Odds are correct at the time of publication and subject to change.
Looking at the latest head-to-head odds, the bookmakers currently have the Cardinals at $2.50 and the Tigers at $1.56.
The Cardinals are listed as 1.5-run underdogs against the Tigers, with odds of $1.85 available at TAB.
For the favourite Tigers (-1.5) to cover the line, TAB offers odds of $1.98.
The over/under for total runs scored is set at 7.5 with TAB, which has odds of $1.91 for the over and $1.91 for the under.
According to Stats Insider's model, the Cardinals (+1.5) are predicted to cover the line 55% of the time, while the 7.5-run over/under is expected to stay under 54% of the time.
Cardinals vs Tigers: Betting Tips
- Head to Head: St. Louis at $2.50 with TAB
- Line: Cardinals +1.5 at $1.85 with TAB
- Total Runs: Under 7.5 at $1.91 with TAB
Our Cardinals vs Tigers betting tips are based on detailed modelling and betting intelligence to bring you the best possible advice every time.
While the Tigers have a higher chance of winning the game, betting on the Cardinals to win is our recommended option due to the 2.8% edge found when comparing our data-led probabilities to the odds currently available.
Making use of the edges published here at Stats Insider is crucial to achieving long-term success as a punter.
Cardinals vs Tigers: Prediction
Stats Insider provides full betting coverage of the St. Louis vs Detroit game on Wednesday, including data-driven predictions and live win probabilitiestips.
Remember, our model updates regularly, so bookmark this article for the latest betting predictions before the St. Louis vs Detroit game.
As always, see Stats Insider's Best Bets for the best tips on every MLB game, as well as predictions for a wide range of other sports.
Cardinals vs Tigers: Essential Details
The match-up between the Cardinals and Tigers at Busch Stadium is scheduled to commence at 9:45am AEST on Wednesday.
- Teams: St. Louis Cardinals vs Detroit Tigers
- Date: Wednesday 21 May 2025
- Time: 9:45am AEST
- Venue: Busch Stadium
All dates and times in this article are in Australian Eastern Standard Time (AEST), unless otherwise stated.
Conclusion
Our St. Louis vs Detroit predictions have been made thanks to 10,000 data-driven simulations of the game, all curated by our team of experienced data scientists and analysts. We use cutting-edge technology and machine learning to ensure our MLB tips are trustworthy and reliable, giving you the confidence to make informed decisions.
If you choose to use our MLB predictions for betting purposes, it's crucial to gamble responsibly and manage your finances effectively. For free and confidential support, call 1800 858 858 or visit gamblinghelponline.org.au.
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