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Cardinals vs Royals Prediction and MLB Tips - 6 June 2025

The St. Louis Cardinals will take on the Kansas City Royals in MLB action at Busch Stadium on Friday, starting at 9:45am AEST.

Matthew Liberatore (3-4, 3.08 ERA) will start on the mound for the Cardinals, while the Royals will counter with Cole Ragans (2-3, 4.53 ERA).

This article features Stats Insider's free betting tips for the Cardinals vs Royals game, plus the latest betting odds in Australia.

Who Will Win?

Using trusted computer power and data, Stats Insider has simulated the outcome of Friday's St. Louis vs Kansas City MLB game 10,000 times.

Our leading predictive analytics model gives the Cardinals a 51% chance of beating the Royals at Busch Stadium.

Cardinals vs Royals: Odds

The latest betting odds in Australia for Friday's MLB game at Busch Stadium are listed here:

  • Head to Head: Cardinals $1.83, Royals $2.00
  • Line: Cardinals +1.5 ($1.46), Royals -1.5 ($2.77)
  • Total (Over/Under 7.5 Runs): Over $1.91, Under $1.91

Odds are correct at the time of publication and subject to change.

Looking at the latest head-to-head odds, the bookmakers currently have the Cardinals at $1.83 and the Royals at $2.00.

The Cardinals are 1.5-run underdogs against the Royals, with odds of $1.46 available at TAB.

For the favourite Royals (-1.5) to cover the line, TAB offers odds of $2.77.

The over/under for total runs scored is set at 7.5 with TAB, which has odds of $1.91 for the over and $1.91 for the under.

According to Stats Insider's analytics model, the Cardinals (+1.5) are predicted to cover the line 54% of the time, while the 7.5-run over/under is expected to stay under 54% of the time.

Cardinals vs Royals: Best Bets

  • Head to Head: Kansas City at $2.00 with TAB
  • Line: Royals -1.5 at $2.77 with TAB
  • Total Runs: Under 7.5 at $1.91 with TAB

When you see a 🔥, that means it's one of Stats Insider's best bets for today across all sports.

Stats Insider's Cardinals vs Royals betting tips are based on detailed modelling and betting expertise to help you place more informed bets with your chosen online bookie.

And while the Cardinals have a higher chance of winning the game, betting on the Royals to win is our preferred option because of the 1.1% edge found when comparing our data-led probabilities to the odds currently available.

Taking advantage of the edges published on Stats Insider is pivotal to achieving long-term profitability.

Although the Cardinals are more likely to cover the line, our best bet of Royals -1.5 is based on the chance of that happening, as projected by our predictive analytics model, and the best odds available.

Cardinals vs Royals: Prediction

Stats Insider provides full coverage of the St. Louis vs Kansas City game on Friday, including data-driven predictions and the best betting tips.

Our model updates regularly, so keep checking this page for the latest betting analysis before the St. Louis vs Kansas City game.

As always, see our Best Bets to get betting tips for every MLB game, as well as predictions for a wide range of other sports.

Cardinals vs Royals: Essential Details

The match-up between the Cardinals and Royals at Busch Stadium is scheduled to begin at 9:45am AEST on Friday.

All dates and times mentioned in this article are in Australian Eastern Standard Time (AEST), unless otherwise stated.

Conclusion

Our St. Louis vs Kansas City predictions are based on 10,000 data-driven simulations of the game, all curated by our team of skilled data scientists and analysts. We use cutting-edge technology and machine learning to ensure our MLB tips are accurate and reliable, giving you the knowledge you need to make informed decisions with confidence.

If you decide to use our predictions for betting purposes, it's vital that you gamble responsibly and keep track of your money. For free and confidential support, call 1800 858 858 or visit gamblinghelponline.org.au.

More on MLB

Stats Insider is your home for betting on the MLB in Australia, with the latest MLB betting news, predictions for every MLB game, and futures probabilities for the MLB.

Stats Insider

Stats Insider, Australia's leading predictive analytics website, offers Australian sports fans innovative tools and content to enhance their enjoyment of major sporting events both domestically and internationally. Our goal is to transform the sports fan experience by providing readily accessible, data-driven content for sports enthusiasts like us.

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