Cardinals vs Royals Prediction and MLB Tips - 4 June 2025
Last updated: Jun 3, 2025, 5:30AM | Published: Jun 2, 2025, 6:30PM
The St. Louis Cardinals will sqaure off with the Kansas City Royals in MLB action at Busch Stadium on Wednesday, starting at 9:45am AEST.
Andre Pallante (4-3, 4.23 ERA) will start on the mound for the Cardinals, while the Royals will counter with Michael Lorenzen (3-6, 4.33 ERA).
This article features Stats Insider's free betting tips for the Cardinals vs Royals game, as well as the latest betting odds in Australia.
Who Will Win?
Based on trusted machine learning and data, Stats Insider has simulated the result of Wednesday's St. Louis vs Kansas City MLB match-up 10,000 times.
Our independent predictive analytics model currently gives the Cardinals a 57% chance of beating the Royals at Busch Stadium.
Cardinals vs Royals: Odds
The latest betting odds in Australia for Wednesday's MLB game at Busch Stadium are shown here:
- Head to Head: Cardinals $1.68, Royals $2.25
- Line: Cardinals -1.5 ($2.45), Royals +1.5 ($1.56)
- Total (Over/Under 8.5 Runs): Over $1.91, Under $1.91
Odds are correct at the time of publication and subject to change.
Looking at the latest head-to-head odds, the bookmakers currently have the Cardinals at $1.68 and the Royals at $2.25.
The Cardinals are 1.5-run favourites against the Royals, with odds of $2.45 available at TAB.
For the underdog Royals (+1.5) to cover the line, TAB offers odds of $1.56.
The over/under for total runs scored is set at 8.5 with TAB, which has odds of $1.91 for the over and $1.91 for the under.
According to Stats Insider's model, the Royals (+1.5) are predicted to cover the line 63% of the time, while the 8.5-run over/under is expected to stay under 52% of the time.
Cardinals vs Royals: Betting Tips
- Head to Head: Kansas City at $2.25 with TAB
- Line: Royals +1.5 at $1.56 with TAB
- Total Runs: Under 8.5 at $1.91 with TAB
Stats Insider's Cardinals vs Royals betting tips are based on market-leading simulations and gambling expertise to provide you with the best possible advice 24/7.
While the Cardinals have a higher chance of winning the game, betting on the Royals to win is our preferred option because of the edge found when comparing our data-led probabilities to the odds currently available.
Making use of the edges seen on Stats Insider is one of the keys to being profitable in the long run.
Cardinals vs Royals: Prediction
Stats Insider provides full coverage of the St. Louis vs Kansas City game on Wednesday, including data-driven predictions and live win probabilitiestips.
Our model updates frequently, so keep checking this page for the latest betting analysis before the St. Louis vs Kansas City game.
As always, see our Best Bets to get the best tips on every MLB game, as well as predictions for a wide range of other sports.
Cardinals vs Royals: Essential Details
The game between the Cardinals and Royals at Busch Stadium is scheduled to begin at 9:45am AEST on Wednesday.
- Teams: St. Louis Cardinals vs Kansas City Royals
- Date: Wednesday 4 June 2025
- Time: 9:45am AEST
- Venue: Busch Stadium
All dates and times mentioned in this article are in Australian Eastern Standard Time (AEST), unless otherwise noted.
Conclusion
Our St. Louis vs Kansas City predictions have been made based on 10,000 data-driven simulations of the game, all curated by our team of expert data scientists and analysts. We use cutting-edge technology and machine learning to ensure our MLB tips are accurate and reliable, giving you the confidence to make informed decisions.
If you decide to use our MLB predictions for betting purposes, it's vital that you gamble responsibly and know when to stop. For free and confidential support, call 1800 858 858 or visit gamblinghelponline.org.au.
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