Cardinals vs Reds Prediction and MLB Tips - 18 September 2025
Last updated: Sep 17, 2025, 5:15PM | Published: Sep 16, 2025, 7:29PM
The St. Louis Cardinals will face the Cincinnati Reds in MLB action at Busch Stadium on Thursday, commencing at 3:15am AEST.
Andre Pallante (6-14, 5.23 ERA) will get the ball for the Cardinals, up against Brady Singer (13-10, 3.94 ERA) for the Reds.
This article features Stats Insider's best betting tips for the Cardinals vs Reds game, along with the latest betting odds in Australia.
Who Will Win?
Utilising trusted machine learning and data, Stats Insider has simulated the outcome of Thursday's St. Louis vs Cincinnati MLB match-up 10,000 times.
Our independent predictive analytics model is currently unable to split the two teams, giving both the Cardinals and the Reds an equal 50% chance of winning the game.
Cardinals vs Reds: Odds
The current betting odds in Australia for Thursday's MLB game at Busch Stadium are listed below:
- Head to Head: Cardinals $2.00, Reds $1.83
- Line: Cardinals +1.5 ($1.61), Reds -1.5 ($2.40)
- Total (Over/Under 8.5 Runs): Over $1.91, Under $1.91
Odds are correct at the time of publication and subject to change.
Looking at the latest head-to-head odds, the bookmakers currently have the Cardinals at $2.00 and the Reds at $1.83.
The Cardinals are 1.5-run underdogs against the Reds, with odds of $1.61 available at TAB.
For the favourite Reds (-1.5) to cover the line, TAB offers odds of $2.40.
The over/under for total runs scored is set at 8.5 with TAB, which has odds of $1.91 for the over and $1.91 for the under.
According to Stats Insider's model, the Cardinals (+1.5) are predicted to cover the line 63% of the time, while the 8.5-run over/under is expected to is considered an equal 50-50 chance of hitting.
Cardinals vs Reds: Best Bets
- Head to Head: St. Louis at $2.00 with TAB
- Line: Cardinals +1.5 at $1.61 with TAB
- Total Runs: Under 8.5 at $1.91 with TAB
Our Cardinals vs Reds best bets are based on detailed modelling and betting experience to help you place more informed bets with your chosen online bookie.
Cardinals vs Reds: Prediction
Stats Insider provides full coverage of the St. Louis vs Cincinnati game on Thursday, including data-driven predictions and free tips.
Our model updates regularly, so bookmark this page for the latest betting predictions before the St. Louis vs Cincinnati match-up.
As always, see Stats Insider's Best Bets to get betting tips for every MLB game, plus predictions for a wide range of other sports.
Cardinals vs Reds: Essential Details
The game between the Cardinals and Reds at Busch Stadium is scheduled to commence at 3:15am AEST on Thursday.
- Teams: St. Louis Cardinals vs Cincinnati Reds
- Date: Thursday 18 September 2025
- Time: 3:15am AEST
- Venue: Busch Stadium
All dates and times in this article are in Australian Eastern Standard Time (AEST), unless otherwise stated.
Conclusion
Our St. Louis vs Cincinnati predictions are the result of 10,000 data-driven simulations of the game, all curated by our team of expert data scientists and analysts. We use the latest in predictive analytics technology and machine learning to ensure our MLB tips are accurate and reliable, so that you can make informed decisions with confidence.
If you decide to use our MLB predictions for betting purposes, it's vital that you gamble responsibly and keep track of your money. For free and confidential support, call 1800 858 858 or visit gamblinghelponline.org.au.
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